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Mixed epithelial/mesenchymal metaplastic breast carcinoma

MedGen UID:
307769
Concept ID:
C1513365
Neoplastic Process
Synonyms: Breast Carcinosarcoma; breast carcinosarcoma; Breast Mixed Epithelial/Mesenchymal Metaplastic Carcinoma; Mixed Epithelial/Mesenchymal Metaplastic Breast Carcinoma; mixed epithelial/mesenchymal metaplastic breast carcinoma; mixed type metaplastic breast cancer
 
Monarch Initiative: MONDO:0004274

Definition

An invasive breast carcinoma characterized by the presence of a mesenchymal cellular component. The mesenchymal cellular component ranges from cartilaginous and osseous, to purely sarcomatous. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed epithelial/mesenchymal metaplastic breast carcinoma

Recent clinical studies

Etiology

Febres-Aldana CA, Alvarez Moreno JC, Rivera M, Kaplan S, Paramo J, Poppiti R
Pathol Int 2020 Feb;70(2):101-107. Epub 2019 Dec 23 doi: 10.1111/pin.12887. PMID: 31867792
McCart Reed AE, Kalaw E, Nones K, Bettington M, Lim M, Bennett J, Johnstone K, Kutasovic JR, Saunus JM, Kazakoff S, Xu Q, Wood S, Holmes O, Leonard C, Reid LE, Black D, Niland C, Ferguson K, Gresshoff I, Raghavendra A, Harvey K, Cooper C, Liu C, Kalinowski L, Reid AS, Davidson M, Pearson JV, Pathmanathan N, Tse G, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox SB, O'Toole SA, Simpson PT, Waddell N, Lakhani SR
J Pathol 2019 Feb;247(2):214-227. Epub 2018 Dec 20 doi: 10.1002/path.5184. PMID: 30350370
Abd El Hafez A, Shawky Ael-A
Breast Dis 2013 Jan 1;34(2):67-75. doi: 10.3233/BD-130353. PMID: 24077354
Jebsen PW, Hagmar BM, Nesland JM
Acta Cytol 1991 Jul-Aug;35(4):396-402. PMID: 1718111

Diagnosis

Xu D, Hou L
Pol J Pathol 2019;70(3):174-182. doi: 10.5114/pjp.2019.90393. PMID: 31820860
McCart Reed AE, Kalaw E, Nones K, Bettington M, Lim M, Bennett J, Johnstone K, Kutasovic JR, Saunus JM, Kazakoff S, Xu Q, Wood S, Holmes O, Leonard C, Reid LE, Black D, Niland C, Ferguson K, Gresshoff I, Raghavendra A, Harvey K, Cooper C, Liu C, Kalinowski L, Reid AS, Davidson M, Pearson JV, Pathmanathan N, Tse G, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox SB, O'Toole SA, Simpson PT, Waddell N, Lakhani SR
J Pathol 2019 Feb;247(2):214-227. Epub 2018 Dec 20 doi: 10.1002/path.5184. PMID: 30350370
Ruess DA, Kayser C, Neubauer J, Fichtner-Feigl S, Hopt UT, Wittel UA
Pancreas 2017 Oct;46(9):1225-1233. doi: 10.1097/MPA.0000000000000904. PMID: 28902796
Abd El Hafez A, Shawky Ael-A
Breast Dis 2013 Jan 1;34(2):67-75. doi: 10.3233/BD-130353. PMID: 24077354
Tampaki EC, Tampakis A, Agrogiannis G, Kavantzas N, Kontzoglou K, Kouraklis G
Onkologie 2013;36(9):506-9. Epub 2013 Aug 19 doi: 10.1159/000354638. PMID: 24051928

Prognosis

Xu D, Hou L
Pol J Pathol 2019;70(3):174-182. doi: 10.5114/pjp.2019.90393. PMID: 31820860
McCart Reed AE, Kalaw E, Nones K, Bettington M, Lim M, Bennett J, Johnstone K, Kutasovic JR, Saunus JM, Kazakoff S, Xu Q, Wood S, Holmes O, Leonard C, Reid LE, Black D, Niland C, Ferguson K, Gresshoff I, Raghavendra A, Harvey K, Cooper C, Liu C, Kalinowski L, Reid AS, Davidson M, Pearson JV, Pathmanathan N, Tse G, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox SB, O'Toole SA, Simpson PT, Waddell N, Lakhani SR
J Pathol 2019 Feb;247(2):214-227. Epub 2018 Dec 20 doi: 10.1002/path.5184. PMID: 30350370
Ruess DA, Kayser C, Neubauer J, Fichtner-Feigl S, Hopt UT, Wittel UA
Pancreas 2017 Oct;46(9):1225-1233. doi: 10.1097/MPA.0000000000000904. PMID: 28902796
Min Kim H, Kim SK, Jung WH, Koo JS
Tumour Biol 2015 Feb;36(2):1207-12. Epub 2014 Oct 25 doi: 10.1007/s13277-014-2735-x. PMID: 25344213
Yigit S, Pehlivan FS, Evcim G, Etit D
Pathol Res Pract 2012 Mar 15;208(3):147-50. Epub 2012 Feb 21 doi: 10.1016/j.prp.2011.12.014. PMID: 22361036

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