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Polysomy 10

MedGen UID:
307987
•Concept ID:
C1514213
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolysomy 10

Professional guidelines

PubMed

Genetic findings in treatment-naïve and proton-beam-radiated iris melanomas.
Krishna Y, Kalirai H, Thornton S, Damato BE, Heimann H, Coupland SE
Br J Ophthalmol 2016 Jul;100(7):1012-1016. Epub 2016 Apr 20 doi: 10.1136/bjophthalmol-2015-308301. PMID: 27098748
Primary sclerosing cholangitis with equivocal cytology: fluorescence in situ hybridization and serum CA 19-9 predict risk of malignancy.
Barr Fritcher EG, Voss JS, Jenkins SM, Lingineni RK, Clayton AC, Roberts LR, Halling KC, Talwalkar JA, Gores GJ, Kipp BR
Cancer Cytopathol 2013 Dec;121(12):708-17. Epub 2013 Jul 9 doi: 10.1002/cncy.21331. PMID: 23839915
Prenatal diagnosis and management of sex chromosome aneuploidy: a report on 98 cases.
Brun JL, Gangbo F, Wen ZQ, Galant K, Taine L, Maugey-Laulom B, Roux D, Mangione R, Horovitz J, Saura R
Prenat Diagn 2004 Mar;24(3):213-8. doi: 10.1002/pd.834. PMID: 15057956

Recent clinical studies

Etiology

Evaluating the Significance of Pancreatobiliary Fluorescence In Situ Hybridization Polysomy on Prognosis in De Novo Cholangiocarcinoma.
Ji H, Barr Fritcher EG, Yin J, Bainter TM, Zemla TJ, Gores GJ, Halling KC, Kipp BR, Roberts LR
Clin Transl Gastroenterol 2022 Oct 1;13(10):e00523. doi: 10.14309/ctg.0000000000000523. PMID: 36000989Free PMC Article
The clinical and prognostic role of ALK in glioblastoma.
Franceschi E, De Biase D, Di Nunno V, Pession A, Tosoni A, Gatto L, Tallini G, Visani M, Lodi R, Bartolini S, Brandes AA
Pathol Res Pract 2021 May;221:153447. Epub 2021 Apr 15 doi: 10.1016/j.prp.2021.153447. PMID: 33887544
Erlotinib efficacy in NSCLC patients with high polysomy of chromosome 7 and EGFR/KRas wild-type tumors.
Toffalorio F, de Marinis F, Conforti F, Spitaleri G, Catania C, Noberasco C, Lazzari C, Vecchio F, Stufano V, Barberis M, De Pas T
J Thorac Oncol 2015 Feb;10(2):392-6. doi: 10.1097/JTO.0000000000000355. PMID: 25611230
Genetic alterations and protein expression of HER2 and chromosome 17 polysomy in breast cancer.
Zhu X, Lu Y, Lu H, Yang W, Tu X, Cai X, Zhou X
Hum Pathol 2011 Oct;42(10):1499-504. Epub 2011 Jun 14 doi: 10.1016/j.humpath.2010.04.023. PMID: 21676436
Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy.
Ross JS
Drug News Perspect 2009 Mar;22(2):93-106. doi: 10.1358/dnp.2009.22.2.1334452. PMID: 19330168

Diagnosis

Evaluating the Significance of Pancreatobiliary Fluorescence In Situ Hybridization Polysomy on Prognosis in De Novo Cholangiocarcinoma.
Ji H, Barr Fritcher EG, Yin J, Bainter TM, Zemla TJ, Gores GJ, Halling KC, Kipp BR, Roberts LR
Clin Transl Gastroenterol 2022 Oct 1;13(10):e00523. doi: 10.14309/ctg.0000000000000523. PMID: 36000989Free PMC Article
A clinical perspective on the 2016 WHO brain tumor classification and routine molecular diagnostics.
van den Bent MJ, Weller M, Wen PY, Kros JM, Aldape K, Chang S
Neuro Oncol 2017 May 1;19(5):614-624. doi: 10.1093/neuonc/now277. PMID: 28339700Free PMC Article
Cystic and necrotic papillary renal cell carcinoma: prognosis, morphology, immunohistochemical, and molecular-genetic profile of 10 cases.
Peckova K, Martinek P, Pivovarcikova K, Vanecek T, Alaghehbandan R, Prochazkova K, Montiel DP, Hora M, Skenderi F, Ulamec M, Rotterova P, Daum O, Ferda J, Davidson W, Ondic O, Dubova M, Michal M, Hes O
Ann Diagn Pathol 2017 Feb;26:23-30. Epub 2016 Oct 20 doi: 10.1016/j.anndiagpath.2016.10.007. PMID: 28038707
The HER2 gene and HER2 protein status and chromosome 17 polysomy in gastric cancer cells in own material.
Ciesielski M, Kruszewski WJ, Śmiałek U, Walczak J, Szajewski M, Szefel J, Wydra J, Kawecki K
Appl Immunohistochem Mol Morphol 2015 Feb;23(2):113-7. doi: 10.1097/PAI.0000000000000070. PMID: 25203430
Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy.
Ross JS
Drug News Perspect 2009 Mar;22(2):93-106. doi: 10.1358/dnp.2009.22.2.1334452. PMID: 19330168

Therapy

Erlotinib efficacy in NSCLC patients with high polysomy of chromosome 7 and EGFR/KRas wild-type tumors.
Toffalorio F, de Marinis F, Conforti F, Spitaleri G, Catania C, Noberasco C, Lazzari C, Vecchio F, Stufano V, Barberis M, De Pas T
J Thorac Oncol 2015 Feb;10(2):392-6. doi: 10.1097/JTO.0000000000000355. PMID: 25611230
Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer.
Murray S, Karavasilis V, Bobos M, Razis E, Papadopoulos S, Christodoulou C, Kosmidis P, Fountzilas G
J Exp Clin Cancer Res 2012 Sep 19;31(1):77. doi: 10.1186/1756-9966-31-77. PMID: 22992338Free PMC Article
Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations.
Galimi F, Torti D, Sassi F, Isella C, Corà D, Gastaldi S, Ribero D, Muratore A, Massucco P, Siatis D, Paraluppi G, Gonella F, Maione F, Pisacane A, David E, Torchio B, Risio M, Salizzoni M, Capussotti L, Perera T, Medico E, Di Renzo MF, Comoglio PM, Trusolino L, Bertotti A
Clin Cancer Res 2011 May 15;17(10):3146-56. Epub 2011 Mar 29 doi: 10.1158/1078-0432.CCR-10-3377. PMID: 21447729
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group.
van den Bent MJ, Dubbink HJ, Marie Y, Brandes AA, Taphoorn MJ, Wesseling P, Frenay M, Tijssen CC, Lacombe D, Idbaih A, van Marion R, Kros JM, Dinjens WN, Gorlia T, Sanson M
Clin Cancer Res 2010 Mar 1;16(5):1597-604. Epub 2010 Feb 16 doi: 10.1158/1078-0432.CCR-09-2902. PMID: 20160062
Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy.
Ross JS
Drug News Perspect 2009 Mar;22(2):93-106. doi: 10.1358/dnp.2009.22.2.1334452. PMID: 19330168

Prognosis

Evaluating the Significance of Pancreatobiliary Fluorescence In Situ Hybridization Polysomy on Prognosis in De Novo Cholangiocarcinoma.
Ji H, Barr Fritcher EG, Yin J, Bainter TM, Zemla TJ, Gores GJ, Halling KC, Kipp BR, Roberts LR
Clin Transl Gastroenterol 2022 Oct 1;13(10):e00523. doi: 10.14309/ctg.0000000000000523. PMID: 36000989Free PMC Article
The clinical and prognostic role of ALK in glioblastoma.
Franceschi E, De Biase D, Di Nunno V, Pession A, Tosoni A, Gatto L, Tallini G, Visani M, Lodi R, Bartolini S, Brandes AA
Pathol Res Pract 2021 May;221:153447. Epub 2021 Apr 15 doi: 10.1016/j.prp.2021.153447. PMID: 33887544
Mesenchymal-epithelial transition gene amplification and protein overexpression in stage IV pulmonary adenocarcinoma.
Ando R, Fujino M, Kominami-Kiriyama A, Ito A, Koide T, Ito M
Jpn J Clin Oncol 2019 Aug 1;49(8):755-761. doi: 10.1093/jjco/hyz060. PMID: 31329925
Cystic and necrotic papillary renal cell carcinoma: prognosis, morphology, immunohistochemical, and molecular-genetic profile of 10 cases.
Peckova K, Martinek P, Pivovarcikova K, Vanecek T, Alaghehbandan R, Prochazkova K, Montiel DP, Hora M, Skenderi F, Ulamec M, Rotterova P, Daum O, Ferda J, Davidson W, Ondic O, Dubova M, Michal M, Hes O
Ann Diagn Pathol 2017 Feb;26:23-30. Epub 2016 Oct 20 doi: 10.1016/j.anndiagpath.2016.10.007. PMID: 28038707
Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy.
Ross JS
Drug News Perspect 2009 Mar;22(2):93-106. doi: 10.1358/dnp.2009.22.2.1334452. PMID: 19330168

Clinical prediction guides

The clinical and prognostic role of ALK in glioblastoma.
Franceschi E, De Biase D, Di Nunno V, Pession A, Tosoni A, Gatto L, Tallini G, Visani M, Lodi R, Bartolini S, Brandes AA
Pathol Res Pract 2021 May;221:153447. Epub 2021 Apr 15 doi: 10.1016/j.prp.2021.153447. PMID: 33887544
MDM2 dual-color in situ hybridization (DISH) aids the diagnosis of intimal sarcomas.
Jimbo N, Komatsu M, Itoh T, Hirose T
Cardiovasc Pathol 2019 Nov-Dec;43:107142. Epub 2019 Jul 16 doi: 10.1016/j.carpath.2019.07.001. PMID: 31442826
The HER2 gene and HER2 protein status and chromosome 17 polysomy in gastric cancer cells in own material.
Ciesielski M, Kruszewski WJ, Śmiałek U, Walczak J, Szajewski M, Szefel J, Wydra J, Kawecki K
Appl Immunohistochem Mol Morphol 2015 Feb;23(2):113-7. doi: 10.1097/PAI.0000000000000070. PMID: 25203430
Genetic alterations and protein expression of HER2 and chromosome 17 polysomy in breast cancer.
Zhu X, Lu Y, Lu H, Yang W, Tu X, Cai X, Zhou X
Hum Pathol 2011 Oct;42(10):1499-504. Epub 2011 Jun 14 doi: 10.1016/j.humpath.2010.04.023. PMID: 21676436
Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy.
Ross JS
Drug News Perspect 2009 Mar;22(2):93-106. doi: 10.1358/dnp.2009.22.2.1334452. PMID: 19330168

Recent systematic reviews

EGFR mutation testing on cytological and histological samples in non-small cell lung cancer: a Polish, single institution study and systematic review of European incidence.
Szumera-Ciećkiewicz A, Olszewski WT, Tysarowski A, Kowalski DM, Głogowski M, Krzakowski M, Siedlecki JA, Wągrodzki M, Prochorec-Sobieszek M
Int J Clin Exp Pathol 2013;6(12):2800-12. Epub 2013 Nov 15 PMID: 24294366Free PMC Article

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