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Borderline Peritoneal Serous Tumor

MedGen UID:
308042
•Concept ID:
C1514418
•
Neoplastic Process
Synonyms: Peritoneal SBT; Peritoneal Serous Borderline Tumor; Primary Borderline Peritoneal Epithelial Neoplasm; Primary Borderline Peritoneal Epithelial Tumor; Primary Peritoneal Borderline Epithelial Neoplasm; Primary Peritoneal Borderline Epithelial Tumor; Primary Peritoneal Serous Borderline Tumor; Primary Peritoneal Serous Borderline Tumor/ Primary Peritoneal Atypical Proliferative Serous Tumor

Definition

A serous epithelial tumor that arises from the peritoneum and histologically resembles the serous borderline tumors that arise from the ovary. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBorderline Peritoneal Serous Tumor

Professional guidelines

PubMed

Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Chen LM, Cristea M, DeRosa M, Eisenhauer EL, Gershenson DM, Gray HJ, Grisham R, Hakam A, Jain A, Karam A, Konecny GE, Leath CA, Liu J, Mahdi H, Martin L, Matei D, McHale M, McLean K, Miller DS, O'Malley DM, Percac-Lima S, Ratner E, Remmenga SW, Vargas R, Werner TL, Zsiros E, Burns JL, Engh AM
J Natl Compr Canc Netw 2021 Feb 2;19(2):191-226. doi: 10.6004/jnccn.2021.0007. PMID: 33545690
Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria.
Hauptmann S, Friedrich K, Redline R, Avril S
Virchows Arch 2017 Feb;470(2):125-142. Epub 2016 Dec 27 doi: 10.1007/s00428-016-2040-8. PMID: 28025670Free PMC Article
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698

Recent clinical studies

Etiology

Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.
Gershenson DM, Miller A, Brady WE, Paul J, Carty K, Rodgers W, Millan D, Coleman RL, Moore KN, Banerjee S, Connolly K, Secord AA, O'Malley DM, Dorigo O, Gaillard S, Gabra H, Slomovitz B, Hanjani P, Farley J, Churchman M, Ewing A, Hollis RL, Herrington CS, Huang HQ, Wenzel L, Gourley C
Lancet 2022 Feb 5;399(10324):541-553. doi: 10.1016/S0140-6736(21)02175-9. PMID: 35123694Free PMC Article
Brenner Borderline Ovarian Tumor: A Case Series and Literature Review.
Ricotta G, Maulard A, Genestie C, Pautier P, Leary A, Chargari C, Candiani M, Morice P, Gouy S
Ann Surg Oncol 2021 Oct;28(11):6714-6720. Epub 2021 Mar 25 doi: 10.1245/s10434-021-09879-y. PMID: 33768396
Low-grade serous ovarian cancer: State of the science.
Slomovitz B, Gourley C, Carey MS, Malpica A, Shih IM, Huntsman D, Fader AN, Grisham RN, Schlumbrecht M, Sun CC, Ludemann J, Cooney GA, Coleman R, Sood AK, Mahdi H, Wong KK, Covens A, O'Malley DM, Lecuru F, Cobb LP, Caputo TA, May T, Huang M, Siemon J, Fernández ML, Ray-Coquard I, Gershenson DM
Gynecol Oncol 2020 Mar;156(3):715-725. Epub 2020 Jan 20 doi: 10.1016/j.ygyno.2019.12.033. PMID: 31969252
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698
Borderline ovarian tumors.
Link CJ Jr, Reed E, Sarosy G, Kohn EC
Am J Med 1996 Aug;101(2):217-25. doi: 10.1016/s0002-9343(96)80079-9. PMID: 8757363

Diagnosis

Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.
Gershenson DM, Miller A, Brady WE, Paul J, Carty K, Rodgers W, Millan D, Coleman RL, Moore KN, Banerjee S, Connolly K, Secord AA, O'Malley DM, Dorigo O, Gaillard S, Gabra H, Slomovitz B, Hanjani P, Farley J, Churchman M, Ewing A, Hollis RL, Herrington CS, Huang HQ, Wenzel L, Gourley C
Lancet 2022 Feb 5;399(10324):541-553. doi: 10.1016/S0140-6736(21)02175-9. PMID: 35123694Free PMC Article
Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Chen LM, Cristea M, DeRosa M, Eisenhauer EL, Gershenson DM, Gray HJ, Grisham R, Hakam A, Jain A, Karam A, Konecny GE, Leath CA, Liu J, Mahdi H, Martin L, Matei D, McHale M, McLean K, Miller DS, O'Malley DM, Percac-Lima S, Ratner E, Remmenga SW, Vargas R, Werner TL, Zsiros E, Burns JL, Engh AM
J Natl Compr Canc Netw 2021 Feb 2;19(2):191-226. doi: 10.6004/jnccn.2021.0007. PMID: 33545690
Low-grade serous ovarian cancer: State of the science.
Slomovitz B, Gourley C, Carey MS, Malpica A, Shih IM, Huntsman D, Fader AN, Grisham RN, Schlumbrecht M, Sun CC, Ludemann J, Cooney GA, Coleman R, Sood AK, Mahdi H, Wong KK, Covens A, O'Malley DM, Lecuru F, Cobb LP, Caputo TA, May T, Huang M, Siemon J, Fernández ML, Ray-Coquard I, Gershenson DM
Gynecol Oncol 2020 Mar;156(3):715-725. Epub 2020 Jan 20 doi: 10.1016/j.ygyno.2019.12.033. PMID: 31969252
Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria.
Hauptmann S, Friedrich K, Redline R, Avril S
Virchows Arch 2017 Feb;470(2):125-142. Epub 2016 Dec 27 doi: 10.1007/s00428-016-2040-8. PMID: 28025670Free PMC Article
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698

Therapy

Advancements in Low-Grade Serous Carcinoma of the Ovary and Peritoneum.
Grisham RN, Chui MH
Curr Oncol Rep 2022 Nov;24(11):1549-1555. Epub 2022 Aug 13 doi: 10.1007/s11912-022-01315-y. PMID: 35962920Free PMC Article
Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.
Gershenson DM, Miller A, Brady WE, Paul J, Carty K, Rodgers W, Millan D, Coleman RL, Moore KN, Banerjee S, Connolly K, Secord AA, O'Malley DM, Dorigo O, Gaillard S, Gabra H, Slomovitz B, Hanjani P, Farley J, Churchman M, Ewing A, Hollis RL, Herrington CS, Huang HQ, Wenzel L, Gourley C
Lancet 2022 Feb 5;399(10324):541-553. doi: 10.1016/S0140-6736(21)02175-9. PMID: 35123694Free PMC Article
Low-grade serous ovarian cancer: State of the science.
Slomovitz B, Gourley C, Carey MS, Malpica A, Shih IM, Huntsman D, Fader AN, Grisham RN, Schlumbrecht M, Sun CC, Ludemann J, Cooney GA, Coleman R, Sood AK, Mahdi H, Wong KK, Covens A, O'Malley DM, Lecuru F, Cobb LP, Caputo TA, May T, Huang M, Siemon J, Fernández ML, Ray-Coquard I, Gershenson DM
Gynecol Oncol 2020 Mar;156(3):715-725. Epub 2020 Jan 20 doi: 10.1016/j.ygyno.2019.12.033. PMID: 31969252
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698
Interventions for the treatment of borderline ovarian tumours.
Faluyi O, Mackean M, Gourley C, Bryant A, Dickinson HO
Cochrane Database Syst Rev 2010 Sep 8;2010(9):CD007696. doi: 10.1002/14651858.CD007696.pub2. PMID: 20824864Free PMC Article

Prognosis

Advancements in Low-Grade Serous Carcinoma of the Ovary and Peritoneum.
Grisham RN, Chui MH
Curr Oncol Rep 2022 Nov;24(11):1549-1555. Epub 2022 Aug 13 doi: 10.1007/s11912-022-01315-y. PMID: 35962920Free PMC Article
Brenner Borderline Ovarian Tumor: A Case Series and Literature Review.
Ricotta G, Maulard A, Genestie C, Pautier P, Leary A, Chargari C, Candiani M, Morice P, Gouy S
Ann Surg Oncol 2021 Oct;28(11):6714-6720. Epub 2021 Mar 25 doi: 10.1245/s10434-021-09879-y. PMID: 33768396
Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria.
Hauptmann S, Friedrich K, Redline R, Avril S
Virchows Arch 2017 Feb;470(2):125-142. Epub 2016 Dec 27 doi: 10.1007/s00428-016-2040-8. PMID: 28025670Free PMC Article
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698
Borderline ovarian tumors.
Link CJ Jr, Reed E, Sarosy G, Kohn EC
Am J Med 1996 Aug;101(2):217-25. doi: 10.1016/s0002-9343(96)80079-9. PMID: 8757363

Clinical prediction guides

BAP1 and Claudin-4, But Not MTAP, Reliably Distinguish Borderline and Low-grade Serous Ovarian Tumors From Peritoneal Mesothelioma.
Devins KM, Zukerberg L, Watkins JC, Hung YP, Oliva E
Int J Gynecol Pathol 2023 Mar 1;42(2):159-166. Epub 2022 May 20 doi: 10.1097/PGP.0000000000000877. PMID: 35512220
Role of MRI in characterizing serous borderline ovarian tumor and its subtypes: Correlation of MRI features with clinicopathological characteristics.
Li K, Song F, Yu L, Shi H, Wang J, Cheng X
Eur J Radiol 2022 Feb;147:110112. Epub 2021 Dec 21 doi: 10.1016/j.ejrad.2021.110112. PMID: 34972058
Brenner Borderline Ovarian Tumor: A Case Series and Literature Review.
Ricotta G, Maulard A, Genestie C, Pautier P, Leary A, Chargari C, Candiani M, Morice P, Gouy S
Ann Surg Oncol 2021 Oct;28(11):6714-6720. Epub 2021 Mar 25 doi: 10.1245/s10434-021-09879-y. PMID: 33768396
Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria.
Hauptmann S, Friedrich K, Redline R, Avril S
Virchows Arch 2017 Feb;470(2):125-142. Epub 2016 Dec 27 doi: 10.1007/s00428-016-2040-8. PMID: 28025670Free PMC Article
Needleoscopic Conservative Staging of Borderline Ovarian Tumor.
Gueli Alletti S, Rossitto C, Perrone E, Cianci S, De Blasis I, Fagotti A, Scambia G
J Minim Invasive Gynecol 2017 May-Jun;24(4):529-530. Epub 2016 Oct 27 doi: 10.1016/j.jmig.2016.10.009. PMID: 27989810

Recent systematic reviews

Interventions for the treatment of borderline ovarian tumours.
Faluyi O, Mackean M, Gourley C, Bryant A, Dickinson HO
Cochrane Database Syst Rev 2010 Sep 8;2010(9):CD007696. doi: 10.1002/14651858.CD007696.pub2. PMID: 20824864Free PMC Article

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