U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Testicular pure germ cell tumor

MedGen UID:
308089
Concept ID:
C1514608
Neoplastic Process
Synonyms: Testicular Pure Germ Cell Tumor; testicular pure germ cell tumor; testicular Pure germ cell tumor; testicular Pure germ cell tumour
 
Monarch Initiative: MONDO:0002874

Definition

A germ cell tumor that arises from the testis and is characterized by the presence of one histologic component. This category includes seminoma, teratoma, embryonal carcinoma, yolk sac tumor, and choriocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular pure germ cell tumor

Professional guidelines

PubMed

Casadei C, Schepisi G, Menna C, Chovanec M, Gurioli G, Gallà V, Altavilla A, Marcellini M, Bellia SR, Lolli C, Mego M, Rosti G, De Giorgi U
Future Oncol 2019 Apr;15(12):1347-1352. Epub 2019 Mar 18 doi: 10.2217/fon-2018-0850. PMID: 30880465
Khader J, Salem A, Abuodeh Y, Almousa A, Farah N, Abdelrahman F
BMC Urol 2012 Apr 24;12:10. doi: 10.1186/1471-2490-12-10. PMID: 22531005Free PMC Article
Winter C, Albers P
Nat Rev Endocrinol 2011 Jan;7(1):43-53. Epub 2010 Nov 30 doi: 10.1038/nrendo.2010.196. PMID: 21116298

Recent clinical studies

Etiology

Orsatti A, Sirolli M, Ambrosi F, Franceschini T, Giunchi F, Franchini E, Grillini M, Massari F, Mollica V, Bianchi FM, Colecchia M, Fiorentino M, Ricci C
Pathol Res Pract 2022 Sep;237:154044. Epub 2022 Jul 28 doi: 10.1016/j.prp.2022.154044. PMID: 35930824
Arasaratnam M, Balakrishnar B, Crumbaker M, Turner S, Hayden AJ, Brooks A, Patel MI, Lau H, Woo H, Bariol S, Gurney H
Asia Pac J Clin Oncol 2022 Apr;18(2):e23-e31. Epub 2021 Jun 21 doi: 10.1111/ajco.13548. PMID: 34152083
Kao CS, Bangs CD, Aldrete G, Cherry AM, Ulbright TM
Am J Surg Pathol 2018 Dec;42(12):1662-1673. doi: 10.1097/PAS.0000000000001164. PMID: 30256256
Becherer A
Methods Mol Biol 2011;727:225-41. doi: 10.1007/978-1-61779-062-1_13. PMID: 21331937
Porcaro AB, Antoniolli SZ, Maffei N, Beltrami P, Bassetto MA, Curti P
Arch Ital Urol Androl 2002 Jun;74(2):81-5. PMID: 12161942

Diagnosis

Namavari N, Taheri L, Hooshmand F, Dousthaghi MH, Rahmanian V
BMC Urol 2023 Jun 3;23(1):102. doi: 10.1186/s12894-023-01271-0. PMID: 37270552Free PMC Article
Arasaratnam M, Balakrishnar B, Crumbaker M, Turner S, Hayden AJ, Brooks A, Patel MI, Lau H, Woo H, Bariol S, Gurney H
Asia Pac J Clin Oncol 2022 Apr;18(2):e23-e31. Epub 2021 Jun 21 doi: 10.1111/ajco.13548. PMID: 34152083
Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A
Radiat Oncol 2011 Aug 8;6:90. doi: 10.1186/1748-717X-6-90. PMID: 21819630Free PMC Article
Val-Bernal JF, Azcarretazábal T, Torío B, Mayorga M
Pathol Int 1999 Feb;49(2):185-9. doi: 10.1046/j.1440-1827.1999.00844.x. PMID: 10355976

Therapy

von Amsberg G, Hamilton R, Papachristofilou A
Oncol Res Treat 2018;41(6):360-363. Epub 2018 May 16 doi: 10.1159/000489408. PMID: 29763926
Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A
Radiat Oncol 2011 Aug 8;6:90. doi: 10.1186/1748-717X-6-90. PMID: 21819630Free PMC Article
Schmidberger H, Bamberg M, Meisner C, Classen J, Winkler C, Hartmann M, Templin R, Wiegel T, Dornoff W, Ross D, Thiel HJ, Martini C, Haase W
Int J Radiat Oncol Biol Phys 1997 Sep 1;39(2):321-6. doi: 10.1016/s0360-3016(97)00155-7. PMID: 9308934
Schuette J, Niederle N, Scheulen ME, Seeber S, Schmidt CG
Br J Cancer 1985 Apr;51(4):467-72. doi: 10.1038/bjc.1985.67. PMID: 2579665Free PMC Article
Kaplan JH, Kudish HG, Sacks SA
Postgrad Med 1981 Dec;70(6):125-7, 130-1. doi: 10.1080/00325481.1981.11715938. PMID: 6796949

Prognosis

Namavari N, Taheri L, Hooshmand F, Dousthaghi MH, Rahmanian V
BMC Urol 2023 Jun 3;23(1):102. doi: 10.1186/s12894-023-01271-0. PMID: 37270552Free PMC Article
Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A
Radiat Oncol 2011 Aug 8;6:90. doi: 10.1186/1748-717X-6-90. PMID: 21819630Free PMC Article
Becherer A
Methods Mol Biol 2011;727:225-41. doi: 10.1007/978-1-61779-062-1_13. PMID: 21331937
Velasco A, Riquelme E, Schultz M, Wistuba II, Villarroel L, Pizarro J, Berlin A, Ittmann M, Koh MS, Leach FS
Cancer Biol Ther 2004 Oct;3(10):977-82. Epub 2004 Oct 2 doi: 10.4161/cbt.3.10.1135. PMID: 15467433
Porcaro AB, Antoniolli SZ, Maffei N, Beltrami P, Bassetto MA, Curti P
Arch Ital Urol Androl 2002 Jun;74(2):81-5. PMID: 12161942

Clinical prediction guides

Orsatti A, Sirolli M, Ambrosi F, Franceschini T, Giunchi F, Franchini E, Grillini M, Massari F, Mollica V, Bianchi FM, Colecchia M, Fiorentino M, Ricci C
Pathol Res Pract 2022 Sep;237:154044. Epub 2022 Jul 28 doi: 10.1016/j.prp.2022.154044. PMID: 35930824
von Amsberg G, Hamilton R, Papachristofilou A
Oncol Res Treat 2018;41(6):360-363. Epub 2018 May 16 doi: 10.1159/000489408. PMID: 29763926
Becherer A
Methods Mol Biol 2011;727:225-41. doi: 10.1007/978-1-61779-062-1_13. PMID: 21331937
Schmidberger H, Bamberg M, Meisner C, Classen J, Winkler C, Hartmann M, Templin R, Wiegel T, Dornoff W, Ross D, Thiel HJ, Martini C, Haase W
Int J Radiat Oncol Biol Phys 1997 Sep 1;39(2):321-6. doi: 10.1016/s0360-3016(97)00155-7. PMID: 9308934
Schuette J, Niederle N, Scheulen ME, Seeber S, Schmidt CG
Br J Cancer 1985 Apr;51(4):467-72. doi: 10.1038/bjc.1985.67. PMID: 2579665Free PMC Article

Recent systematic reviews

Ruf CG, Schmidt S, Kliesch S, Oing C, Pfister D, Busch J, Heinzelbecker J, Winter C, Zengerling F, Albers P, Oechsle K, Krege S, Lackner J, Dieckmann KP
World J Urol 2022 Dec;40(12):2889-2900. Epub 2022 Sep 15 doi: 10.1007/s00345-022-04145-6. PMID: 36107211Free PMC Article
Zengerling F, Beyersdorff D, Busch J, Heinzelbecker J, Pfister D, Ruf C, Winter C, Albers P, Kliesch S, Schmidt S
World J Urol 2022 Dec;40(12):2879-2887. Epub 2022 Jul 29 doi: 10.1007/s00345-022-04063-7. PMID: 35906286Free PMC Article
Raynald, Yang H, Zhang X, Ma'ruf L, Li C, Jiang T
Neurochirurgie 2021 Nov;67(6):587-598. Epub 2021 Mar 19 doi: 10.1016/j.neuchi.2021.02.014. PMID: 33753128

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...