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Gain of Chromosome 17

MedGen UID:
309191
Concept ID:
C1517392
Cell or Molecular Dysfunction
Synonym: Chromosome 17 Amplification

Definition

A cytogenetic abnormality that refers to the allelic gain of all or part of chromosome 17. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 17

Professional guidelines

PubMed

Niehr F, Eder T, Pilz T, Konschak R, Treue D, Klauschen F, Bockmayr M, Türkmen S, Jöhrens K, Budach V, Tinhofer I
Clin Cancer Res 2018 Jan 1;24(1):158-168. Epub 2017 Oct 23 doi: 10.1158/1078-0432.CCR-17-2410. PMID: 29061642
Merz M, Hielscher T, Seckinger A, Hose D, Mai EK, Raab MS, Goldschmidt H, Jauch A, Hillengass J
Am J Hematol 2016 Nov;91(11):E473-E477. Epub 2016 Sep 3 doi: 10.1002/ajh.24533. PMID: 27508939
Tajiri T, Shono K, Tanaka S, Suita S
Surgery 2002 Jan;131(1 Suppl):S283-7. doi: 10.1067/msy.2002.119964. PMID: 11821825

Recent clinical studies

Etiology

Hao S, Lin P, Medeiros LJ, Fang L, Carballo-Zarate AA, Konoplev SN, Sargent RL, Weber DM, Thomas SK, Manasanch EE, Orlowski RZ, Lu X
Mod Pathol 2017 Oct;30(10):1378-1386. Epub 2017 Jun 30 doi: 10.1038/modpathol.2017.63. PMID: 28664940Free PMC Article
Ramaswamy V, Remke M, Bouffet E, Bailey S, Clifford SC, Doz F, Kool M, Dufour C, Vassal G, Milde T, Witt O, von Hoff K, Pietsch T, Northcott PA, Gajjar A, Robinson GW, Padovani L, André N, Massimino M, Pizer B, Packer R, Rutkowski S, Pfister SM, Taylor MD, Pomeroy SL
Acta Neuropathol 2016 Jun;131(6):821-31. Epub 2016 Apr 4 doi: 10.1007/s00401-016-1569-6. PMID: 27040285Free PMC Article
Rossi D, Terzi-di-Bergamo L, De Paoli L, Cerri M, Ghilardi G, Chiarenza A, Bulian P, Visco C, Mauro FR, Morabito F, Cortelezzi A, Zaja F, Forconi F, Laurenti L, Del Giudice I, Gentile M, Vincelli I, Motta M, Coscia M, Rigolin GM, Tedeschi A, Neri A, Marasca R, Perbellini O, Moreno C, Del Poeta G, Massaia M, Zinzani PL, Montillo M, Cuneo A, Gattei V, Foà R, Gaidano G
Blood 2015 Oct 15;126(16):1921-4. Epub 2015 Aug 14 doi: 10.1182/blood-2015-05-647925. PMID: 26276669Free PMC Article
Büschges R, Ichimura K, Weber RG, Reifenberger G, Collins VP
Brain Pathol 2002 Apr;12(2):145-53. doi: 10.1111/j.1750-3639.2002.tb00429.x. PMID: 11958368Free PMC Article
Wilhelmsen KC
Cell Mol Life Sci 1998 Sep;54(9):920-4. doi: 10.1007/s000180050221. PMID: 9791534Free PMC Article

Diagnosis

Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K
Nature 2020 Sep;585(7825):440-446. Epub 2020 Sep 9 doi: 10.1038/s41586-020-2710-1. PMID: 32908304Free PMC Article
Starling CE, Sabra J, Brady B, Horton M, Traweek ST
Diagn Cytopathol 2019 Sep;47(9):930-934. Epub 2019 May 23 doi: 10.1002/dc.24216. PMID: 31120625
Marescalco MS, Capizzi C, Condorelli DF, Barresi V
J Oral Pathol Med 2014 Jan;43(1):20-7. Epub 2013 Jun 10 doi: 10.1111/jop.12087. PMID: 23750501
Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, Barbarotto E, Cimmino A, Adair B, Wojcik SE, Valeri N, Calore F, Sampath D, Fanini F, Vannini I, Musuraca G, Dell'Aquila M, Alder H, Davuluri RV, Rassenti LZ, Negrini M, Nakamura T, Amadori D, Kay NE, Rai KR, Keating MJ, Kipps TJ, Calin GA, Croce CM
JAMA 2011 Jan 5;305(1):59-67. doi: 10.1001/jama.2010.1919. PMID: 21205967Free PMC Article
Bowcock AM, Barker JN
J Am Acad Dermatol 2003 Aug;49(2 Suppl):S51-6. doi: 10.1016/s0190-9622(03)01135-6. PMID: 12894126

Therapy

Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K
Nature 2020 Sep;585(7825):440-446. Epub 2020 Sep 9 doi: 10.1038/s41586-020-2710-1. PMID: 32908304Free PMC Article
Starling CE, Sabra J, Brady B, Horton M, Traweek ST
Diagn Cytopathol 2019 Sep;47(9):930-934. Epub 2019 May 23 doi: 10.1002/dc.24216. PMID: 31120625
Lamanna N, O'Brien S
Hematology Am Soc Hematol Educ Program 2016 Dec 2;2016(1):137-145. doi: 10.1182/asheducation-2016.1.137. PMID: 27913472Free PMC Article
Tarpgaard LS, Qvortrup C, Nygård SB, Nielsen SL, Andersen DR, Jensen NF, Stenvang J, Detlefsen S, Brünner N, Pfeiffer P
BMC Cancer 2016 Feb 11;16:91. doi: 10.1186/s12885-016-2124-5. PMID: 26867764Free PMC Article
Rossi D, Terzi-di-Bergamo L, De Paoli L, Cerri M, Ghilardi G, Chiarenza A, Bulian P, Visco C, Mauro FR, Morabito F, Cortelezzi A, Zaja F, Forconi F, Laurenti L, Del Giudice I, Gentile M, Vincelli I, Motta M, Coscia M, Rigolin GM, Tedeschi A, Neri A, Marasca R, Perbellini O, Moreno C, Del Poeta G, Massaia M, Zinzani PL, Montillo M, Cuneo A, Gattei V, Foà R, Gaidano G
Blood 2015 Oct 15;126(16):1921-4. Epub 2015 Aug 14 doi: 10.1182/blood-2015-05-647925. PMID: 26276669Free PMC Article

Prognosis

Nakazawa A
Pathol Int 2021 Apr;71(4):232-244. Epub 2021 Mar 3 doi: 10.1111/pin.13085. PMID: 33657257
Lee K, Jang MH, Chung YR, Lee Y, Kang E, Kim SW, Kim YJ, Kim JH, Kim IA, Park SY
Hum Pathol 2017 Mar;61:111-120. Epub 2016 Dec 15 doi: 10.1016/j.humpath.2016.12.004. PMID: 27989787
Jian Y, Chen X, Zhou H, Zhu W, Liu N, Geng C, Chen W
Medicine (Baltimore) 2016 May;95(19):e3521. doi: 10.1097/MD.0000000000003521. PMID: 27175647Free PMC Article
Ramaswamy V, Remke M, Bouffet E, Bailey S, Clifford SC, Doz F, Kool M, Dufour C, Vassal G, Milde T, Witt O, von Hoff K, Pietsch T, Northcott PA, Gajjar A, Robinson GW, Padovani L, André N, Massimino M, Pizer B, Packer R, Rutkowski S, Pfister SM, Taylor MD, Pomeroy SL
Acta Neuropathol 2016 Jun;131(6):821-31. Epub 2016 Apr 4 doi: 10.1007/s00401-016-1569-6. PMID: 27040285Free PMC Article
Bowcock AM, Barker JN
J Am Acad Dermatol 2003 Aug;49(2 Suppl):S51-6. doi: 10.1016/s0190-9622(03)01135-6. PMID: 12894126

Clinical prediction guides

Dong L, Meng F, Wu L, Mitchell AV, Block CJ, Zhang B, Craig DB, Jang H, Chen W, Yang Q, Wu G
Int J Oncol 2017 Oct;51(4):1320-1330. Epub 2017 Aug 30 doi: 10.3892/ijo.2017.4108. PMID: 28902361Free PMC Article
Ramaswamy V, Remke M, Bouffet E, Bailey S, Clifford SC, Doz F, Kool M, Dufour C, Vassal G, Milde T, Witt O, von Hoff K, Pietsch T, Northcott PA, Gajjar A, Robinson GW, Padovani L, André N, Massimino M, Pizer B, Packer R, Rutkowski S, Pfister SM, Taylor MD, Pomeroy SL
Acta Neuropathol 2016 Jun;131(6):821-31. Epub 2016 Apr 4 doi: 10.1007/s00401-016-1569-6. PMID: 27040285Free PMC Article
Marescalco MS, Capizzi C, Condorelli DF, Barresi V
J Oral Pathol Med 2014 Jan;43(1):20-7. Epub 2013 Jun 10 doi: 10.1111/jop.12087. PMID: 23750501
Wang G, Zhao Y, Liu X, Wang L, Wu C, Zhang W, Liu W, Zhang P, Cong W, Zhu Y, Zhang L, Chen S, Wan D, Zhao X, Huang W, Gu J
Genes Chromosomes Cancer 2001 Jul;31(3):221-7. doi: 10.1002/gcc.1138. PMID: 11391792
Touchman JW, Anikster Y, Dietrich NL, Maduro VV, McDowell G, Shotelersuk V, Bouffard GG, Beckstrom-Sternberg SM, Gahl WA, Green ED
Genome Res 2000 Feb;10(2):165-73. doi: 10.1101/gr.10.2.165. PMID: 10673275Free PMC Article

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