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Gain of Chromosome 9q34

MedGen UID:
309200
•Concept ID:
C1517427
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 9q34

Recent clinical studies

Etiology

Role of autoimmune hemolytic anemia as an initial indicator for chronic myeloid leukemia: A case report.
Li X, Cai S, Zhong Z, Wang H, Wang L, You Y, Zhang M
Medicine (Baltimore) 2020 Feb;99(9):e19256. doi: 10.1097/MD.0000000000019256. PMID: 32118733Free PMC Article
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Khan FH, Pandian V, Ramraj S, Natarajan M, Aravindan S, Herman TS, Aravindan N
BMC Cancer 2015 Jul 10;15:514. doi: 10.1186/s12885-015-1463-y. PMID: 26159519Free PMC Article
Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma.
Slovak ML, Bedell V, Hsu YH, Estrine DB, Nowak NJ, Delioukina ML, Weiss LM, Smith DD, Forman SJ
Clin Cancer Res 2011 May 15;17(10):3443-54. Epub 2011 Mar 8 doi: 10.1158/1078-0432.CCR-10-1071. PMID: 21385932Free PMC Article
Complex patterns of chromosome 9 alterations including the p16INK4a locus in Wilms tumours.
Natrajan R, Warren W, Messahel B, Reis-Filho JS, Brundler MA, Dome JS, Grundy PE, Vujanic G, Pritchard-Jones K, Jones C
J Clin Pathol 2008 Jan;61(1):95-102. Epub 2007 Mar 16 doi: 10.1136/jcp.2007.047159. PMID: 17369505
Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity.
Weng WH, Lerner M, Grandér D, Ahlén J, Villablanca A, Pang ST, Wejde J, Lui WO, Larsson C
Int J Oncol 2005 Jan;26(1):5-16. PMID: 15586219

Diagnosis

First prenatal diagnosis of a 'pure' 9q34.3 deletion (Kleefstra syndrome): A case report and literature review.
Guterman S, Hervé B, Rivière J, Fauvert D, Clement P, Vialard F
J Obstet Gynaecol Res 2018 Mar;44(3):570-575. Epub 2017 Nov 21 doi: 10.1111/jog.13517. PMID: 29160022
De novo 9q gain in an infant with tetralogy of Fallot with absent pulmonary valve: Patient report and review of congenital heart disease in 9q duplication syndrome.
Amarillo IE, O'Connor S, Lee CK, Willing M, Wambach JA
Am J Med Genet A 2015 Dec;167A(12):2966-74. Epub 2015 Aug 19 doi: 10.1002/ajmg.a.37296. PMID: 26768185Free PMC Article
Molecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord.
Bidinotto LT, Scapulatempo-Neto C, Mackay A, de Almeida GC, Scheithauer BW, Berardinelli GN, Torrieri R, Clara CA, Feltrin LT, Viana-Pereira M, Varella-Garcia M, Jones C, Reis RM
PLoS One 2015;10(9):e0137690. Epub 2015 Sep 15 doi: 10.1371/journal.pone.0137690. PMID: 26371886Free PMC Article
Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome.
Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG 2nd, Loeffler JS, Louis DN, Mohapatra G
J Neuropathol Exp Neurol 2009 Oct;68(10):1155-65. doi: 10.1097/NEN.0b013e3181ba3952. PMID: 19918127Free PMC Article
Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics.
Cremer FW, Bila J, Buck I, Kartal M, Hose D, Ittrich C, Benner A, Raab MS, Theil AC, Moos M, Goldschmidt H, Bartram CR, Jauch A
Genes Chromosomes Cancer 2005 Oct;44(2):194-203. doi: 10.1002/gcc.20231. PMID: 16001433

Therapy

Role of autoimmune hemolytic anemia as an initial indicator for chronic myeloid leukemia: A case report.
Li X, Cai S, Zhong Z, Wang H, Wang L, You Y, Zhang M
Medicine (Baltimore) 2020 Feb;99(9):e19256. doi: 10.1097/MD.0000000000019256. PMID: 32118733Free PMC Article
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Khan FH, Pandian V, Ramraj S, Natarajan M, Aravindan S, Herman TS, Aravindan N
BMC Cancer 2015 Jul 10;15:514. doi: 10.1186/s12885-015-1463-y. PMID: 26159519Free PMC Article
Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome.
Loukopoulos P, Shibata T, Katoh H, Kokubu A, Sakamoto M, Yamazaki K, Kosuge T, Kanai Y, Hosoda F, Imoto I, Ohki M, Inazawa J, Hirohashi S
Cancer Sci 2007 Mar;98(3):392-400. Epub 2007 Jan 12 doi: 10.1111/j.1349-7006.2007.00395.x. PMID: 17233815Free PMC Article

Prognosis

Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome.
Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG 2nd, Loeffler JS, Louis DN, Mohapatra G
J Neuropathol Exp Neurol 2009 Oct;68(10):1155-65. doi: 10.1097/NEN.0b013e3181ba3952. PMID: 19918127Free PMC Article
Complex patterns of chromosome 9 alterations including the p16INK4a locus in Wilms tumours.
Natrajan R, Warren W, Messahel B, Reis-Filho JS, Brundler MA, Dome JS, Grundy PE, Vujanic G, Pritchard-Jones K, Jones C
J Clin Pathol 2008 Jan;61(1):95-102. Epub 2007 Mar 16 doi: 10.1136/jcp.2007.047159. PMID: 17369505
Loss of 1p36, gain of 8q24, and loss of 9q34 are associated with stroma percentage of colorectal cancer.
Fijneman RJ, Carvalho B, Postma C, Mongera S, van Hinsbergh VW, Meijer GA
Cancer Lett 2007 Dec 18;258(2):223-9. Epub 2007 Oct 30 doi: 10.1016/j.canlet.2007.09.013. PMID: 17977645
Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics.
Cremer FW, Bila J, Buck I, Kartal M, Hose D, Ittrich C, Benner A, Raab MS, Theil AC, Moos M, Goldschmidt H, Bartram CR, Jauch A
Genes Chromosomes Cancer 2005 Oct;44(2):194-203. doi: 10.1002/gcc.20231. PMID: 16001433
Amplification of the steroidogenic factor 1 gene in childhood adrenocortical tumors.
Figueiredo BC, Cavalli LR, Pianovski MA, Lalli E, Sandrini R, Ribeiro RC, Zambetti G, DeLacerda L, Rodrigues GA, Haddad BR
J Clin Endocrinol Metab 2005 Feb;90(2):615-9. Epub 2004 Nov 16 doi: 10.1210/jc.2004-0942. PMID: 15546904

Clinical prediction guides

Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias.
Burmeister T, Gröger D, Kühn A, Hoelzer D, Thiel E, Reinhardt R
DNA Repair (Amst) 2011 Nov 10;10(11):1131-7. Epub 2011 Sep 22 doi: 10.1016/j.dnarep.2011.08.010. PMID: 21944569
Common chromosomal abnormalities in mycosis fungoides transformation.
Prochazkova M, Chevret E, Mainhaguiet G, Sobotka J, Vergier B, Belaud-Rotureau MA, Beylot-Barry M, Merlio JP
Genes Chromosomes Cancer 2007 Sep;46(9):828-38. doi: 10.1002/gcc.20469. PMID: 17584911
Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics.
Cremer FW, Bila J, Buck I, Kartal M, Hose D, Ittrich C, Benner A, Raab MS, Theil AC, Moos M, Goldschmidt H, Bartram CR, Jauch A
Genes Chromosomes Cancer 2005 Oct;44(2):194-203. doi: 10.1002/gcc.20231. PMID: 16001433
Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity.
Weng WH, Lerner M, Grandér D, Ahlén J, Villablanca A, Pang ST, Wejde J, Lui WO, Larsson C
Int J Oncol 2005 Jan;26(1):5-16. PMID: 15586219
Comparative genomic and in situ hybridization of germ cell tumors of the infantile testis.
Mostert M, Rosenberg C, Stoop H, Schuyer M, Timmer A, Oosterhuis W, Looijenga L
Lab Invest 2000 Jul;80(7):1055-64. doi: 10.1038/labinvest.3780110. PMID: 10908150

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