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Bone Marrow Involvement

MedGen UID:
309258
•Concept ID:
C1517677
•
Finding

Definition

Infiltration of the bone marrow by a malignant neoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone Marrow Involvement

Professional guidelines

PubMed

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
POEMS Syndrome: 2019 Update on diagnosis, risk-stratification, and management.
Dispenzieri A
Am J Hematol 2019 Jul;94(7):812-827. Epub 2019 May 23 doi: 10.1002/ajh.25495. PMID: 31012139

Recent clinical studies

Etiology

POEMS syndrome: 2021 Update on diagnosis, risk-stratification, and management.
Dispenzieri A
Am J Hematol 2021 Jul 1;96(7):872-888. Epub 2021 May 31 doi: 10.1002/ajh.26240. PMID: 34000085
Myeloid sarcoma.
Shahin OA, Ravandi F
Curr Opin Hematol 2020 Mar;27(2):88-94. doi: 10.1097/MOH.0000000000000571. PMID: 31904666
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
How We Manage Patients with Plasmacytomas.
Fotiou D, Dimopoulos MA, Kastritis E
Curr Hematol Malig Rep 2018 Jun;13(3):227-235. doi: 10.1007/s11899-018-0452-z. PMID: 29667156
POEMS Syndrome: Therapeutic Options.
Jaccard A
Hematol Oncol Clin North Am 2018 Feb;32(1):141-151. doi: 10.1016/j.hoc.2017.09.011. PMID: 29157615

Diagnosis

Myeloid sarcoma.
Shahin OA, Ravandi F
Curr Opin Hematol 2020 Mar;27(2):88-94. doi: 10.1097/MOH.0000000000000571. PMID: 31904666
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Hepatosplenic T-Cell Lymphomas.
Gowda L, Foss F
Cancer Treat Res 2019;176:185-193. doi: 10.1007/978-3-319-99716-2_9. PMID: 30596219
POEMS Syndrome: Therapeutic Options.
Jaccard A
Hematol Oncol Clin North Am 2018 Feb;32(1):141-151. doi: 10.1016/j.hoc.2017.09.011. PMID: 29157615
Barraquer-Simons Syndrome.
Small JE, Jassam YN, Small KM, Chea P, Popov V, Li S, Srinivasan J
Am J Med Sci 2016 Sep;352(3):280-4. Epub 2016 May 24 doi: 10.1016/j.amjms.2016.05.007. PMID: 27650233

Therapy

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
How I treat microangiopathic hemolytic anemia in patients with cancer.
Thomas MR, Scully M
Blood 2021 Mar 11;137(10):1310-1317. doi: 10.1182/blood.2019003810. PMID: 33512445Free PMC Article
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Lymphoblastic lymphoma.
Cortelazzo S, Ferreri A, Hoelzer D, Ponzoni M
Crit Rev Oncol Hematol 2017 May;113:304-317. Epub 2017 Mar 18 doi: 10.1016/j.critrevonc.2017.03.020. PMID: 28427520

Prognosis

Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts-A follow-up.
Holler A, Cicha I, Eckstein M, Haderlein M, Pöttler M, Rappl A, Iro H, Alexiou C
Cancer Med 2022 Dec;11(24):4743-4755. Epub 2022 May 16 doi: 10.1002/cam4.4816. PMID: 35578404Free PMC Article
Bone marrow involvement in breast cancer.
Sütcüoğlu O, Özdemir N, Yazıcı O, Özet A
Curr Probl Cancer 2022 Feb;46(1):100785. Epub 2021 Aug 15 doi: 10.1016/j.currproblcancer.2021.100785. PMID: 34417058
Myeloid sarcoma.
Shahin OA, Ravandi F
Curr Opin Hematol 2020 Mar;27(2):88-94. doi: 10.1097/MOH.0000000000000571. PMID: 31904666
Imaging of bone marrow involvement in lymphoma: state of the art and future directions.
Kwee TC, de Klerk JM, Nievelstein RA
ScientificWorldJournal 2011 Feb 14;11:391-402. doi: 10.1100/tsw.2011.40. PMID: 21336455Free PMC Article
Bone marrow involvement by hodgkin and non-hodgkin lymphomas.
Zhang QY, Foucar K
Hematol Oncol Clin North Am 2009 Aug;23(4):873-902. doi: 10.1016/j.hoc.2009.04.014. PMID: 19577173

Clinical prediction guides

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
A multicenter study of romiplostim for chemotherapy-induced thrombocytopenia in solid tumors and hematologic malignancies.
Al-Samkari H, Parnes AD, Goodarzi K, Weitzman JI, Connors JM, Kuter DJ
Haematologica 2021 Apr 1;106(4):1148-1157. doi: 10.3324/haematol.2020.251900. PMID: 32499239Free PMC Article
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Childhood mastocytosis.
Torrelo A, Alvarez-Twose I, Escribano L
Curr Opin Pediatr 2012 Aug;24(4):480-6. doi: 10.1097/MOP.0b013e328355b248. PMID: 22790101

Recent systematic reviews

FDG-PET/CT versus bone marrow biopsy in bone marrow involvement in newly diagnosed paediatric lymphoma: a systematic review and meta-analysis.
Li Z, Li C, Chen B, Shi L, Gao F, Wang P, Sun W
J Orthop Surg Res 2021 Aug 9;16(1):482. doi: 10.1186/s13018-021-02521-3. PMID: 34372894Free PMC Article
Systematic review of staging bone marrow involvement in B cell lymphoma by flow cytometry.
Sorigue M, Cañamero E, Miljkovic MD
Blood Rev 2021 May;47:100778. Epub 2020 Nov 8 doi: 10.1016/j.blre.2020.100778. PMID: 33187810
Systematic review and meta-analysis on the diagnostic performance of FDG-PET/CT in detecting bone marrow involvement in newly diagnosed Hodgkin lymphoma: is bone marrow biopsy still necessary?
Adams HJ, Kwee TC, de Keizer B, Fijnheer R, de Klerk JM, Littooij AS, Nievelstein RA
Ann Oncol 2014 May;25(5):921-7. Epub 2013 Dec 18 doi: 10.1093/annonc/mdt533. PMID: 24351400
FDG PET/CT for the detection of bone marrow involvement in diffuse large B-cell lymphoma: systematic review and meta-analysis.
Adams HJ, Kwee TC, de Keizer B, Fijnheer R, de Klerk JM, Nievelstein RA
Eur J Nucl Med Mol Imaging 2014 Mar;41(3):565-74. Epub 2013 Nov 27 doi: 10.1007/s00259-013-2623-4. PMID: 24281821
18F-FDG PET, combined FDG-PET/CT and MRI for evaluation of bone marrow infiltration in staging of lymphoma: a systematic review and meta-analysis.
Wu LM, Chen FY, Jiang XX, Gu HY, Yin Y, Xu JR
Eur J Radiol 2012 Feb;81(2):303-11. Epub 2010 Dec 9 doi: 10.1016/j.ejrad.2010.11.020. PMID: 21145680

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