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Breast lymphoma

MedGen UID:
309939
•Concept ID:
C1704251
•
Neoplastic Process
Synonyms: Breast Lymphoma; breast lymphoma; Lymphoma of Breast; lymphoma of breast; Lymphoma of the Breast; lymphoma of the breast; malignant lymphoma of breast; Primary Breast Lymphoma; primary breast lymphoma
 
Monarch Initiative: MONDO:0003661

Definition

A lymphoma that arises from the breast. There is no history of extramammary breast lymphoma and ipsilateral axillary lymph node involvement does not exclude the diagnosis of primary breast lymphoma. Most patients present with a painless breast lump. The vast majority of cases are B-cell non-Hodgkin lymphomas. Diffuse large B-cell lymphoma, follicular lymphoma, and extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue are the most common types of primary non-Hodgkin lymphoma of the breast. Primary Hodgkin lymphoma of the breast is rare. [from NCI]

Professional guidelines

PubMed

Patterns of treatment and their outcomes in primary breast lymphoma; a comprehensive population-based analysis.
Mustafa Ali MK, Samhouri Y, Law JY, Khan C, Wegner R, Lee ST, Lister J
Breast Cancer 2022 Nov;29(6):1022-1031. Epub 2022 Jul 5 doi: 10.1007/s12282-022-01382-w. PMID: 35788963
Management and outcomes of women diagnosed with primary breast lymphoma: a multi-institution experience.
Lalani N, Winkfield KM, Soto DE, Yeap BY, Ng AK, Mauch PM, Jimenez RB
Breast Cancer Res Treat 2018 May;169(1):197-202. Epub 2018 Jan 22 doi: 10.1007/s10549-018-4671-8. PMID: 29356916
Targeted Cancer Therapy: The Next Generation of Cancer Treatment.
Baudino TA
Curr Drug Discov Technol 2015;12(1):3-20. doi: 10.2174/1570163812666150602144310. PMID: 26033233

Recent clinical studies

Etiology

Primary and Secondary Breast Lymphoma: Focus on Epidemiology and Imaging Features.
Picasso R, Tagliafico A, Calabrese M, Martinoli C, Pistoia F, Rossi A, Zaottini F, Derchi L
Pathol Oncol Res 2020 Jul;26(3):1483-1488. Epub 2019 Aug 20 doi: 10.1007/s12253-019-00730-0. PMID: 31428995
Primary breast lymphoma: A single-centre experience.
Foo MY, Lee WP, Seah CMJ, Kam C, Tan SM
Cancer Rep (Hoboken) 2019 Feb;2(1):e1140. Epub 2018 Oct 17 doi: 10.1002/cnr2.1140. PMID: 32721093Free PMC Article
Primary breast lymphoma.
Cheah CY, Campbell BA, Seymour JF
Cancer Treat Rev 2014 Sep;40(8):900-8. Epub 2014 Jun 6 doi: 10.1016/j.ctrv.2014.05.010. PMID: 24953564
Anaplastic large T-cell lymphoma and breast implants: a review of the literature.
Jewell M, Spear SL, Largent J, Oefelein MG, Adams WP Jr
Plast Reconstr Surg 2011 Sep;128(3):651-661. doi: 10.1097/PRS.0b013e318221db81. PMID: 21865998
Primary breast lymphoma.
Gholam D, Bibeau F, El Weshi A, Bosq J, Ribrag V
Leuk Lymphoma 2003 Jul;44(7):1173-8. doi: 10.1080/1042819031000079195. PMID: 12916870

Diagnosis

Breast lymphoma: General review.
Rezkallah EMN, Elsaify A, Tin SMM, Dey D, Elsaify WM
Breast Dis 2023;42(1):197-205. doi: 10.3233/BD-220051. PMID: 37393489
Thirteen-Centimeter Breast Lymphoma.
Breese RO, Friend K
Am Surg 2022 Aug;88(8):1891-1892. Epub 2022 Apr 14 doi: 10.1177/00031348221084964. PMID: 35420924
Hematolymphoid lesions of the breast.
Hoffmann J, Ohgami RS
Semin Diagn Pathol 2017 Sep;34(5):462-469. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.007. PMID: 28662998
Extranodal Lymphoma of the Breast.
Nicholson BT, Bhatti RM, Glassman L
Radiol Clin North Am 2016 Jul;54(4):711-26. doi: 10.1016/j.rcl.2016.03.005. PMID: 27265604
Primary breast lymphoma.
Cheah CY, Campbell BA, Seymour JF
Cancer Treat Rev 2014 Sep;40(8):900-8. Epub 2014 Jun 6 doi: 10.1016/j.ctrv.2014.05.010. PMID: 24953564

Therapy

Exploring the Feasibility of a Mindfulness-Music Therapy Intervention to Improve Anxiety and Stress in Adolescents and Young Adults with Cancer.
Knoerl R, Mazzola E, Woods H, Buchbinder E, Frazier L, LaCasce A, Li BT, Luskin MR, Phillips CS, Thornton K, Berry DL, Ligibel JA
J Pain Symptom Manage 2022 Apr;63(4):e357-e363. Epub 2021 Dec 8 doi: 10.1016/j.jpainsymman.2021.11.013. PMID: 34896280
Primary and Secondary Breast Lymphoma: Clinical, Pathologic, and Multimodality Imaging Review.
Raj SD, Shurafa M, Shah Z, Raj KM, Fishman MDC, Dialani VM
Radiographics 2019 May-Jun;39(3):610-625. Epub 2019 Mar 29 doi: 10.1148/rg.2019180097. PMID: 30924754
Targeted Cancer Therapy: The Next Generation of Cancer Treatment.
Baudino TA
Curr Drug Discov Technol 2015;12(1):3-20. doi: 10.2174/1570163812666150602144310. PMID: 26033233
Anaplastic large T-cell lymphoma and breast implants: a review of the literature.
Jewell M, Spear SL, Largent J, Oefelein MG, Adams WP Jr
Plast Reconstr Surg 2011 Sep;128(3):651-661. doi: 10.1097/PRS.0b013e318221db81. PMID: 21865998
Primary breast lymphoma.
Gholam D, Bibeau F, El Weshi A, Bosq J, Ribrag V
Leuk Lymphoma 2003 Jul;44(7):1173-8. doi: 10.1080/1042819031000079195. PMID: 12916870

Prognosis

Primary breast lymphoma: A single-centre experience.
Foo MY, Lee WP, Seah CMJ, Kam C, Tan SM
Cancer Rep (Hoboken) 2019 Feb;2(1):e1140. Epub 2018 Oct 17 doi: 10.1002/cnr2.1140. PMID: 32721093Free PMC Article
Hematolymphoid lesions of the breast.
Hoffmann J, Ohgami RS
Semin Diagn Pathol 2017 Sep;34(5):462-469. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.007. PMID: 28662998
Anaplastic large T-cell lymphoma and breast implants: a review of the literature.
Jewell M, Spear SL, Largent J, Oefelein MG, Adams WP Jr
Plast Reconstr Surg 2011 Sep;128(3):651-661. doi: 10.1097/PRS.0b013e318221db81. PMID: 21865998
Non-Hodgkin's lymphoma of the breast: a report of 19 cases and a review of the literature.
Vignot S, Ledoussal V, Nodiot P, Bourguignat A, Janvier M, Mounier N, Chérel P, Floiras JL, Turpin F
Clin Lymphoma 2005 Jun;6(1):37-42. doi: 10.3816/clm.2005.n.025. PMID: 15989705
Primary breast lymphoma.
Gholam D, Bibeau F, El Weshi A, Bosq J, Ribrag V
Leuk Lymphoma 2003 Jul;44(7):1173-8. doi: 10.1080/1042819031000079195. PMID: 12916870

Clinical prediction guides

Patterns of treatment and their outcomes in primary breast lymphoma; a comprehensive population-based analysis.
Mustafa Ali MK, Samhouri Y, Law JY, Khan C, Wegner R, Lee ST, Lister J
Breast Cancer 2022 Nov;29(6):1022-1031. Epub 2022 Jul 5 doi: 10.1007/s12282-022-01382-w. PMID: 35788963
Management and outcomes of women diagnosed with primary breast lymphoma: a multi-institution experience.
Lalani N, Winkfield KM, Soto DE, Yeap BY, Ng AK, Mauch PM, Jimenez RB
Breast Cancer Res Treat 2018 May;169(1):197-202. Epub 2018 Jan 22 doi: 10.1007/s10549-018-4671-8. PMID: 29356916
Hematolymphoid lesions of the breast.
Hoffmann J, Ohgami RS
Semin Diagn Pathol 2017 Sep;34(5):462-469. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.007. PMID: 28662998
Non-Hodgkin's lymphoma of the breast: a report of 19 cases and a review of the literature.
Vignot S, Ledoussal V, Nodiot P, Bourguignat A, Janvier M, Mounier N, Chérel P, Floiras JL, Turpin F
Clin Lymphoma 2005 Jun;6(1):37-42. doi: 10.3816/clm.2005.n.025. PMID: 15989705
Primary breast lymphoma.
Gholam D, Bibeau F, El Weshi A, Bosq J, Ribrag V
Leuk Lymphoma 2003 Jul;44(7):1173-8. doi: 10.1080/1042819031000079195. PMID: 12916870

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