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Cardiac Intramuscular Hemangioma

MedGen UID:
310591
•Concept ID:
C1707300
•
Neoplastic Process
Synonym: Heart Intramuscular Hemangioma

Definition

A hemangioma arising from the myocardium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Intramuscular Hemangioma

Professional guidelines

PubMed

PHACE syndrome: clinical manifestations, diagnostic criteria, and management.
Rotter A, Samorano LP, Rivitti-Machado MC, Oliveira ZNP, Gontijo B
An Bras Dermatol 2018 Jun;93(3):405-411. doi: 10.1590/abd1806-4841.20187693. PMID: 29924216Free PMC Article
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).
Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M; ESC Scientific Document Group
Eur Heart J 2016 Jan 1;37(1):67-119. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv317. PMID: 26320113

Recent clinical studies

Etiology

Hemangioma-related syndromes.
Valdebran M, Wine Lee L
Curr Opin Pediatr 2020 Aug;32(4):498-505. doi: 10.1097/MOP.0000000000000925. PMID: 32692048
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Infantile haemangioma.
Léauté-Labrèze C, Harper JI, Hoeger PH
Lancet 2017 Jul 1;390(10089):85-94. Epub 2017 Jan 13 doi: 10.1016/S0140-6736(16)00645-0. PMID: 28089471
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).
Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M; ESC Scientific Document Group
Eur Heart J 2016 Jan 1;37(1):67-119. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv317. PMID: 26320113
The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification.
Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel
J Thorac Oncol 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630. PMID: 26291008

Diagnosis

Infantile hemangioma. Part 1: Epidemiology, pathogenesis, clinical presentation and assessment.
Rodríguez Bandera AI, Sebaratnam DF, Wargon O, Wong LF
J Am Acad Dermatol 2021 Dec;85(6):1379-1392. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.019. PMID: 34419524
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Cardiac hemangiomas.
Brizard C, Latremouille C, Jebara VA, Acar C, Fabiani JN, Deloche A, Carpentier AF
Ann Thorac Surg 1993 Aug;56(2):390-4. doi: 10.1016/0003-4975(93)91193-q. PMID: 8347036
Cardiac hemangioma.
Chao JC, Reyes CV, Hwang MH
South Med J 1990 Jan;83(1):44-7. doi: 10.1097/00007611-199001000-00014. PMID: 2405498

Therapy

Pulmonary sclerosing pneumocytoma and mortality risk.
Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Infantile hemangiomas: what have we learned from propranolol?
Hagen R, Ghareeb E, Jalali O, Zinn Z
Curr Opin Pediatr 2018 Aug;30(4):499-504. doi: 10.1097/MOP.0000000000000650. PMID: 29846253
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Infantile haemangioma.
Léauté-Labrèze C, Harper JI, Hoeger PH
Lancet 2017 Jul 1;390(10089):85-94. Epub 2017 Jan 13 doi: 10.1016/S0140-6736(16)00645-0. PMID: 28089471
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).
Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M; ESC Scientific Document Group
Eur Heart J 2016 Jan 1;37(1):67-119. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv317. PMID: 26320113

Prognosis

Multifocal cardiac hemangioma.
Vacirca SR, Nardi P, Ferlosio A, Orlandi A, Ruvolo G
J Card Surg 2018 Jun;33(6):310-312. Epub 2018 May 27 doi: 10.1111/jocs.13719. PMID: 29806221
Cardiac Hemangioma: A Comprehensive Analysis of 200 Cases.
Li W, Teng P, Xu H, Ma L, Ni Y
Ann Thorac Surg 2015 Jun;99(6):2246-52. Epub 2015 Apr 25 doi: 10.1016/j.athoracsur.2015.02.064. PMID: 25921258
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Update on infantile hemangiomas.
Lee KC, Bercovitch L
Semin Perinatol 2013 Feb;37(1):49-58. doi: 10.1053/j.semperi.2012.11.003. PMID: 23419763
Neonatal liver tumours.
von Schweinitz D
Semin Neonatol 2003 Oct;8(5):403-10. doi: 10.1016/S1084-2756(03)00092-7. PMID: 15001128

Clinical prediction guides

Safety and efficacy of propranolol for treatment of familial cerebral cavernous malformations (Treat_CCM): a randomised, open-label, blinded-endpoint, phase 2 pilot trial.
Lanfranconi S, Scola E, Meessen JMTA, Pallini R, Bertani GA, Al-Shahi Salman R, Dejana E, Latini R; Treat_CCM Investigators
Lancet Neurol 2023 Jan;22(1):35-44. Epub 2022 Nov 17 doi: 10.1016/S1474-4422(22)00409-4. PMID: 36403580
Pulmonary sclerosing pneumocytoma and mortality risk.
Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Infantile haemangioma.
Léauté-Labrèze C, Harper JI, Hoeger PH
Lancet 2017 Jul 1;390(10089):85-94. Epub 2017 Jan 13 doi: 10.1016/S0140-6736(16)00645-0. PMID: 28089471
Cardiac Hemangioma: A Comprehensive Analysis of 200 Cases.
Li W, Teng P, Xu H, Ma L, Ni Y
Ann Thorac Surg 2015 Jun;99(6):2246-52. Epub 2015 Apr 25 doi: 10.1016/j.athoracsur.2015.02.064. PMID: 25921258
Propranolol for hemangiomas.
Hasan M, Rahman M, Hoque S, Zahid Hossain AK, Khondker L
Pediatr Surg Int 2013 Mar;29(3):257-62. Epub 2012 Dec 18 doi: 10.1007/s00383-012-3220-5. PMID: 23247833

Recent systematic reviews

Sirolimus for diffuse intestinal infantile hemangioma with PHACE features: systematic review.
Kleinman EP, Blei F, Adams D, Greenberger S
Pediatr Res 2023 May;93(6):1470-1479. Epub 2022 Sep 30 doi: 10.1038/s41390-022-02325-z. PMID: 36180586
Interventions for infantile haemangiomas of the skin.
Novoa M, Baselga E, Beltran S, Giraldo L, Shahbaz A, Pardo-Hernandez H, Arevalo-Rodriguez I
Cochrane Database Syst Rev 2018 Apr 18;4(4):CD006545. doi: 10.1002/14651858.CD006545.pub3. PMID: 29667726Free PMC Article
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Parkes Weber syndrome-Diagnostic and management paradigms: A systematic review.
Banzic I, Brankovic M, Maksimović Ž, Davidović L, Marković M, Rančić Z
Phlebology 2017 Jul;32(6):371-383. Epub 2016 Aug 9 doi: 10.1177/0268355516664212. PMID: 27511883
Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: a systematic review of the literature.
Siegel DH, Tefft KA, Kelly T, Johnson C, Metry D, Burrows P, Pope E, Cordisco M, Holland KE, Maheshwari M, Keith P, Garzon M, Hess C, Frieden IJ, Fullerton HJ, Drolet BA
Stroke 2012 Jun;43(6):1672-4. Epub 2012 Mar 22 doi: 10.1161/STROKEAHA.112.650952. PMID: 22442177

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