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Hypothalamic Gangliocytoma

MedGen UID:: 310851
•Concept ID:: C1708403
•: Neoplastic Process

Definition

A tumor characterized by the presence of mature ganglion cells and neuronal differentiation, arising in the hypothalamus. It is often associated with the presence of pituitary gland adenomas. Symptoms include acromegaly and precocious puberty. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHypothalamic Gangliocytoma

Abnormality of the nervous system
- Abnormal nervous system morphology
  - Neoplasm of the nervous system
    - Neoplasm of the peripheral nervous system
      - Autonomic nervous system neoplasm
        Ganglioneuroma
        Hypothalamic Gangliocytoma

Recent clinical studies

Etiology

Application of the orbito-cranial approach in pediatric neurosurgery.

Siomin V, Spektor S, Beni-Adani L, Constantini S
Childs Nerv Syst 2001 Oct;17(10):612-7. doi: 10.1007/s003810100500. PMID: 11685525

Clinical prediction guides

Hypothalamic gangliocytoma. Selective appearance of neurofibrillary changes, granulovacuolar degeneration, and argentophilic bodies.

Kudo M
Acta Pathol Jpn 1986 Aug;36(8):1225-9. doi: 10.1111/j.1440-1827.1986.tb02843.x. PMID: 3022544

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