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Lesion by Focality

MedGen UID:
310926
•Concept ID:
C1708680
•
Finding

Definition

A term referring to the number of anatomic sites affected by a disease. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLesion by Focality

Professional guidelines

PubMed

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
Charidimou A, Boulouis G, Frosch MP, Baron JC, Pasi M, Albucher JF, Banerjee G, Barbato C, Bonneville F, Brandner S, Calviere L, Caparros F, Casolla B, Cordonnier C, Delisle MB, Deramecourt V, Dichgans M, Gokcal E, Herms J, Hernandez-Guillamon M, Jäger HR, Jaunmuktane Z, Linn J, Martinez-Ramirez S, Martínez-Sáez E, Mawrin C, Montaner J, Moulin S, Olivot JM, Piazza F, Puy L, Raposo N, Rodrigues MA, Roeber S, Romero JR, Samarasekera N, Schneider JA, Schreiber S, Schreiber F, Schwall C, Smith C, Szalardy L, Varlet P, Viguier A, Wardlaw JM, Warren A, Wollenweber FA, Zedde M, van Buchem MA, Gurol ME, Viswanathan A, Al-Shahi Salman R, Smith EE, Werring DJ, Greenberg SM
Lancet Neurol 2022 Aug;21(8):714-725. doi: 10.1016/S1474-4422(22)00208-3. PMID: 35841910Free PMC Article
Pathogenesis Based Diagnosis and Treatment of Endometriosis.
Koninckx PR, Fernandes R, Ussia A, Schindler L, Wattiez A, Al-Suwaidi S, Amro B, Al-Maamari B, Hakim Z, Tahlak M
Front Endocrinol (Lausanne) 2021;12:745548. Epub 2021 Nov 25 doi: 10.3389/fendo.2021.745548. PMID: 34899597Free PMC Article
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724

Recent clinical studies

Etiology

Ictal semiology of gelastic seizures.
Mirandola L, Cantalupo G, d'Orsi G, Meletti S, Vaudano AE, Di Vito L, Vignoli A, Tassi L, Pelliccia V
Epilepsy Behav 2023 Mar;140:109025. Epub 2023 Feb 11 doi: 10.1016/j.yebeh.2022.109025. PMID: 36780776
Genetics of Arterial-Wall-Specific Mechanisms in Atherosclerosis: Focus on Mitochondrial Mutations.
Orekhov AN, Ivanova EA, Markin AM, Nikiforov NG, Sobenin IA
Curr Atheroscler Rep 2020 Aug 9;22(10):54. doi: 10.1007/s11883-020-00873-5. PMID: 32772280
Mechanisms for lesion localization in neuromyelitis optica spectrum disorders.
Bradl M, Reindl M, Lassmann H
Curr Opin Neurol 2018 Jun;31(3):325-333. doi: 10.1097/WCO.0000000000000551. PMID: 29465432Free PMC Article
Endoscopic Radiofrequency Ablation of the Pancreas.
Rustagi T, Chhoda A
Dig Dis Sci 2017 Apr;62(4):843-850. Epub 2017 Feb 3 doi: 10.1007/s10620-017-4452-y. PMID: 28160105
Entrapment neuropathies of the lower extremity.
Craig A
PM R 2013 May;5(5 Suppl):S31-40. Epub 2013 Mar 28 doi: 10.1016/j.pmrj.2013.03.029. PMID: 23542774

Diagnosis

Ictal semiology of gelastic seizures.
Mirandola L, Cantalupo G, d'Orsi G, Meletti S, Vaudano AE, Di Vito L, Vignoli A, Tassi L, Pelliccia V
Epilepsy Behav 2023 Mar;140:109025. Epub 2023 Feb 11 doi: 10.1016/j.yebeh.2022.109025. PMID: 36780776
What you need to know about brain abscesses.
De Andres Crespo M, McKinnon C, Halliday J
Br J Hosp Med (Lond) 2020 Aug 2;81(8):1-7. doi: 10.12968/hmed.2020.0103. PMID: 32845766
Adult Focal Epilepsies.
Skidmore CT
Continuum (Minneap Minn) 2016 Feb;22(1 Epilepsy):94-115. doi: 10.1212/CON.0000000000000290. PMID: 26844732
Brachial plexopathies.
Ferrante MA
Continuum (Minneap Minn) 2014 Oct;20(5 Peripheral Nervous System Disorders):1323-42. doi: 10.1212/01.CON.0000455878.60932.37. PMID: 25299285
Entrapment neuropathies of the lower extremity.
Craig A
PM R 2013 May;5(5 Suppl):S31-40. Epub 2013 Mar 28 doi: 10.1016/j.pmrj.2013.03.029. PMID: 23542774

Therapy

Clinical development and potential of photothermal and photodynamic therapies for cancer.
Li X, Lovell JF, Yoon J, Chen X
Nat Rev Clin Oncol 2020 Nov;17(11):657-674. Epub 2020 Jul 22 doi: 10.1038/s41571-020-0410-2. PMID: 32699309
Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial.
Fendler WP, Calais J, Eiber M, Flavell RR, Mishoe A, Feng FY, Nguyen HG, Reiter RE, Rettig MB, Okamoto S, Emmett L, Zacho HD, Ilhan H, Wetter A, Rischpler C, Schoder H, Burger IA, Gartmann J, Smith R, Small EJ, Slavik R, Carroll PR, Herrmann K, Czernin J, Hope TA
JAMA Oncol 2019 Jun 1;5(6):856-863. doi: 10.1001/jamaoncol.2019.0096. PMID: 30920593Free PMC Article
Targeted phototherapy.
Mysore V, Shashikumar BM
Indian J Dermatol Venereol Leprol 2016 Jan-Feb;82(1):1-6. doi: 10.4103/0378-6323.172902. PMID: 26728802
Inflammation and neuroprotection in traumatic brain injury.
Corps KN, Roth TL, McGavern DB
JAMA Neurol 2015 Mar;72(3):355-62. doi: 10.1001/jamaneurol.2014.3558. PMID: 25599342Free PMC Article
The role of BRAF V600 mutation in melanoma.
Ascierto PA, Kirkwood JM, Grob JJ, Simeone E, Grimaldi AM, Maio M, Palmieri G, Testori A, Marincola FM, Mozzillo N
J Transl Med 2012 Jul 9;10:85. doi: 10.1186/1479-5876-10-85. PMID: 22554099Free PMC Article

Prognosis

Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial.
Wu L, Shang R, Sharma P, Zhou W, Liu J, Yao L, Dong Z, Yuan J, Zeng Z, Yu Y, He C, Xiong Q, Li Y, Deng Y, Cao Z, Huang C, Zhou R, Li H, Hu G, Chen Y, Wang Y, He X, Zhu Y, Yu H
Lancet Gastroenterol Hepatol 2021 Sep;6(9):700-708. Epub 2021 Jul 21 doi: 10.1016/S2468-1253(21)00216-8. PMID: 34297944
The case for radiosurgery for brainstem metastases.
Winograd E, Rivers CI, Fenstermaker R, Fabiano A, Plunkett R, Prasad D
J Neurooncol 2019 Jul;143(3):585-595. Epub 2019 May 24 doi: 10.1007/s11060-019-03195-y. PMID: 31127508
Recurrent and metastatic congenital mesoblastic nephroma: where does the evidence stand?
Jehangir S, Kurian JJ, Selvarajah D, Thomas RJ, Holland AJA
Pediatr Surg Int 2017 Nov;33(11):1183-1188. Epub 2017 Aug 30 doi: 10.1007/s00383-017-4149-5. PMID: 28856451
Brainstem tumors: where are we today?
Recinos PF, Sciubba DM, Jallo GI
Pediatr Neurosurg 2007;43(3):192-201. doi: 10.1159/000098831. PMID: 17409788
Schistosomiasis and the kidney.
Barsoum RS
Semin Nephrol 2003 Jan;23(1):34-41. doi: 10.1053/snep.2003.50003a. PMID: 12563599

Clinical prediction guides

Scalp HFO rates are higher for larger lesions.
Cserpan D, Gennari A, Gaito L, Lo Biundo SP, Tuura R, Sarnthein J, Ramantani G
Epilepsia Open 2022 Sep;7(3):496-503. Epub 2022 May 6 doi: 10.1002/epi4.12596. PMID: 35357778Free PMC Article
Clinically applicable artificial intelligence system for dental diagnosis with CBCT.
Ezhov M, Gusarev M, Golitsyna M, Yates JM, Kushnerev E, Tamimi D, Aksoy S, Shumilov E, Sanders A, Orhan K
Sci Rep 2021 Jul 22;11(1):15006. doi: 10.1038/s41598-021-94093-9. PMID: 34294759Free PMC Article
Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial.
Fendler WP, Calais J, Eiber M, Flavell RR, Mishoe A, Feng FY, Nguyen HG, Reiter RE, Rettig MB, Okamoto S, Emmett L, Zacho HD, Ilhan H, Wetter A, Rischpler C, Schoder H, Burger IA, Gartmann J, Smith R, Small EJ, Slavik R, Carroll PR, Herrmann K, Czernin J, Hope TA
JAMA Oncol 2019 Jun 1;5(6):856-863. doi: 10.1001/jamaoncol.2019.0096. PMID: 30920593Free PMC Article
Ultrasound elastographic techniques in focal liver lesions.
Conti CB, Cavalcoli F, Fraquelli M, Conte D, Massironi S
World J Gastroenterol 2016 Mar 7;22(9):2647-56. doi: 10.3748/wjg.v22.i9.2647. PMID: 26973405Free PMC Article
Acoustic radiation force impulse of the liver.
D'Onofrio M, Crosara S, De Robertis R, Canestrini S, Demozzi E, Gallotti A, Pozzi Mucelli R
World J Gastroenterol 2013 Aug 14;19(30):4841-9. doi: 10.3748/wjg.v19.i30.4841. PMID: 23946588Free PMC Article

Recent systematic reviews

Reversible cerebral vasoconstriction syndrome: a comprehensive systematic review.
Song TJ, Lee KH, Li H, Kim JY, Chang K, Kim SH, Han KH, Kim BY, Kronbichler A, Ducros A, Koyanagi A, Jacob L, Kim MS, Yon DK, Lee SW, Yang JM, Hong SH, Ghayda RA, Kang JW, Shin JI, Smith L
Eur Rev Med Pharmacol Sci 2021 May;25(9):3519-3529. doi: 10.26355/eurrev_202105_25834. PMID: 34002826
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724
Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer-Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis.
Perera M, Papa N, Roberts M, Williams M, Udovicich C, Vela I, Christidis D, Bolton D, Hofman MS, Lawrentschuk N, Murphy DG
Eur Urol 2020 Apr;77(4):403-417. Epub 2019 Feb 14 doi: 10.1016/j.eururo.2019.01.049. PMID: 30773328
Extranasopharyngeal angiofibroma revisited.
Windfuhr JP, Vent J
Clin Otolaryngol 2018 Feb;43(1):199-222. Epub 2017 Aug 10 doi: 10.1111/coa.12939. PMID: 28714226
Aphthous ulcers (recurrent).
Staines K, Greenwood M
BMJ Clin Evid 2015 Feb 26;2015 PMID: 25720501Free PMC Article

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