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Malignant Proliferating Pilar Tumor

MedGen UID:
310982
Concept ID:
C1708903
Neoplastic Process
Synonyms: Malignant Pilar Tumor; Malignant Proliferating Trichilemmal Cyst; Malignant Proliferating Trichilemmal Tumor

Definition

A rare malignant neoplasm that arises from the outer root sheath of the hair follicle. It usually occurs in the scalp, face and trunk. Histopathology shows cords of malignant squamous cells infiltrating into the dermis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Proliferating Pilar Tumor

Professional guidelines

PubMed

Nemeh MN, Curtiss P, Nijhawan RI
J Am Acad Dermatol 2024 Jan;90(1):122-124. Epub 2023 Jun 24 doi: 10.1016/j.jaad.2023.05.097. PMID: 37364614
Martínez-Bosch N, Cristóbal H, Iglesias M, Gironella M, Barranco L, Visa L, Calafato D, Jiménez-Parrado S, Earl J, Carrato A, Manero-Rupérez N, Moreno M, Morales A, Guerra C, Navarro P, García de Frutos P
EBioMedicine 2022 Jan;75:103797. Epub 2021 Dec 29 doi: 10.1016/j.ebiom.2021.103797. PMID: 34973624Free PMC Article
LeBoit PE, Sexton M
J Am Acad Dermatol 1993 Oct;29(4):609-18. doi: 10.1016/0190-9622(93)70228-l. PMID: 7691906

Recent clinical studies

Etiology

Moran JMT, DeSimone MS, Mariño-Enríquez A, Russell-Goldman EE, Fletcher CDM, Mochel MC, Hoang MP
Am J Surg Pathol 2023 Oct 1;47(10):1151-1159. Epub 2023 Jul 31 doi: 10.1097/PAS.0000000000002105. PMID: 37515420

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