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Non-Neoplastic Anal Disorder

MedGen UID:
311051
•Concept ID:
C1709245
•
Disease or Syndrome

Definition

A non-neoplastic disorder that affects the anus. Representative examples include hemorrhoids, ulcers, and infections. [from NCI]

Recent clinical studies

Etiology

Risk of Anal Cancer Following Benign Anal Disease and Anal Cancer Precursor Lesions: A Danish Nationwide Cohort Study.
Faber MT, Frederiksen K, Palefsky JM, Kjaer SK
Cancer Epidemiol Biomarkers Prev 2020 Jan;29(1):185-192. Epub 2019 Oct 9 doi: 10.1158/1055-9965.EPI-19-0601. PMID: 31597665
Hepatic progenitor cells in metastatic liver carcinomas.
Delladetsima I, Sakellariou S, Govaere O, Poulaki E, Felekouras E, Tiniakos D
Histopathology 2018 May;72(6):1060-1065. Epub 2018 Feb 14 doi: 10.1111/his.13450. PMID: 29220096
The relationship between the cervical and anal HPV infection in women with cervical intraepithelial neoplasia.
Sehnal B, Dusek L, Cibula D, Zima T, Halaska M, Driak D, Slama J
J Clin Virol 2014 Jan;59(1):18-23. Epub 2013 Nov 23 doi: 10.1016/j.jcv.2013.11.004. PMID: 24315797
Benign anal and perianal polypoid neoplasms and tumor-like lesions.
AbdullGaffar B, Keloth T, Al-Hattawi M, Al Marzouqi M, ElTayeb Y
Pathol Res Pract 2012 Dec 15;208(12):719-25. Epub 2012 Oct 22 doi: 10.1016/j.prp.2012.09.004. PMID: 23089289
Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.
Etienney I, Vuong S, Si-Mohamed A, Fléjou JF, Atienza P, Bauer P; Cytological Diaconesses Group
Cancer 2012 Dec 15;118(24):6031-8. Epub 2012 Jun 6 doi: 10.1002/cncr.27671. PMID: 22674290

Diagnosis

Risk of Anal Cancer Following Benign Anal Disease and Anal Cancer Precursor Lesions: A Danish Nationwide Cohort Study.
Faber MT, Frederiksen K, Palefsky JM, Kjaer SK
Cancer Epidemiol Biomarkers Prev 2020 Jan;29(1):185-192. Epub 2019 Oct 9 doi: 10.1158/1055-9965.EPI-19-0601. PMID: 31597665
Tumours and inflammatory lesions of the anal canal and perianal skin revisited: an update and practical approach.
Dawson H, Serra S
J Clin Pathol 2015 Dec;68(12):971-81. doi: 10.1136/jclinpath-2015-203056. PMID: 26602415
Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.
Etienney I, Vuong S, Si-Mohamed A, Fléjou JF, Atienza P, Bauer P; Cytological Diaconesses Group
Cancer 2012 Dec 15;118(24):6031-8. Epub 2012 Jun 6 doi: 10.1002/cncr.27671. PMID: 22674290
The use of cytospin monolayer technique in the cytological diagnosis of vulval and anal disease.
Levine TS, Rolfe KJ, Crow J, Styles S, Perrett CW, Maclean AB, Reid WM
Cytopathology 2001 Oct;12(5):297-305. doi: 10.1046/j.1365-2303.2001.00348.x. PMID: 11722509

Therapy

Risk of Anal Cancer Following Benign Anal Disease and Anal Cancer Precursor Lesions: A Danish Nationwide Cohort Study.
Faber MT, Frederiksen K, Palefsky JM, Kjaer SK
Cancer Epidemiol Biomarkers Prev 2020 Jan;29(1):185-192. Epub 2019 Oct 9 doi: 10.1158/1055-9965.EPI-19-0601. PMID: 31597665

Prognosis

Risk of Anal Cancer Following Benign Anal Disease and Anal Cancer Precursor Lesions: A Danish Nationwide Cohort Study.
Faber MT, Frederiksen K, Palefsky JM, Kjaer SK
Cancer Epidemiol Biomarkers Prev 2020 Jan;29(1):185-192. Epub 2019 Oct 9 doi: 10.1158/1055-9965.EPI-19-0601. PMID: 31597665
Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.
Etienney I, Vuong S, Si-Mohamed A, Fléjou JF, Atienza P, Bauer P; Cytological Diaconesses Group
Cancer 2012 Dec 15;118(24):6031-8. Epub 2012 Jun 6 doi: 10.1002/cncr.27671. PMID: 22674290
The use of cytospin monolayer technique in the cytological diagnosis of vulval and anal disease.
Levine TS, Rolfe KJ, Crow J, Styles S, Perrett CW, Maclean AB, Reid WM
Cytopathology 2001 Oct;12(5):297-305. doi: 10.1046/j.1365-2303.2001.00348.x. PMID: 11722509

Clinical prediction guides

Hepatic progenitor cells in metastatic liver carcinomas.
Delladetsima I, Sakellariou S, Govaere O, Poulaki E, Felekouras E, Tiniakos D
Histopathology 2018 May;72(6):1060-1065. Epub 2018 Feb 14 doi: 10.1111/his.13450. PMID: 29220096
The use of cytospin monolayer technique in the cytological diagnosis of vulval and anal disease.
Levine TS, Rolfe KJ, Crow J, Styles S, Perrett CW, Maclean AB, Reid WM
Cytopathology 2001 Oct;12(5):297-305. doi: 10.1046/j.1365-2303.2001.00348.x. PMID: 11722509

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