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Benign Pilar-Associated Mesenchyme Neoplasm

MedGen UID:
312919
Concept ID:
C1706925
Neoplastic Process
Synonym: Benign Pilar-Associated Mesenchyme Tumor

Definition

A mesenchymal neoplasm arising from the pilar sheath of the hair follicle. It is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include fibrofolliculoma, perifollicular fibroma, pilar leiomyoma, and trichogenic myxoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Pilar-Associated Mesenchyme Neoplasm

Professional guidelines

PubMed

Griborio-Guzman AG, Aseyev OI, Shah H, Sadreddini M
Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547
Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897
Roberts ME, Aynardi JT, Chu CS
Gynecol Oncol 2018 Dec;151(3):562-572. Epub 2018 Sep 21 doi: 10.1016/j.ygyno.2018.09.010. PMID: 30244960

Recent clinical studies

Etiology

Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663
Weinschenk RC, Wang WL, Lewis VO
J Am Acad Orthop Surg 2021 Jul 1;29(13):553-562. doi: 10.5435/JAAOS-D-20-01188. PMID: 33595238
Solomon DA, Pekmezci M
Handb Clin Neurol 2020;169:87-99. doi: 10.1016/B978-0-12-804280-9.00005-6. PMID: 32553300
Ulin M, Ali M, Chaudhry ZT, Al-Hendy A, Yang Q
Menopause 2020 Feb;27(2):238-242. doi: 10.1097/GME.0000000000001438. PMID: 31834160Free PMC Article
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178

Diagnosis

Safavi M, Mohammadi F
Fetal Pediatr Pathol 2023 Apr;42(2):281-284. Epub 2022 Jun 24 doi: 10.1080/15513815.2022.2088910. PMID: 35748698
Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663
McKenney JK
Mod Pathol 2018 Jan;31(S1):S133-142. doi: 10.1038/modpathol.2017.155. PMID: 29297486
Mentzel T, Requena L, Brenn T
Surg Pathol Clin 2017 Jun;10(2):319-335. Epub 2017 Mar 14 doi: 10.1016/j.path.2017.01.007. PMID: 28477883
Campagnolo OA, Morais CF, Ughini MO, Aoki CM, Menegazzo M
An Bras Dermatol 2017 Jan-Feb;92(1):101-103. doi: 10.1590/abd1806-4841.20175189. PMID: 28225965Free PMC Article

Therapy

Florenzano P, Hartley IR, Jimenez M, Roszko K, Gafni RI, Collins MT
Calcif Tissue Int 2021 Jan;108(1):128-142. Epub 2020 Jun 5 doi: 10.1007/s00223-020-00691-6. PMID: 32504138
McKinnon E, Xiao P
Arch Pathol Lab Med 2015 Jun;139(6):819-22. doi: 10.5858/arpa.2013-0358-RS. PMID: 26030252
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Connolly EM, Gaffney E, Reynolds JV
Br J Surg 2003 Oct;90(10):1178-86. doi: 10.1002/bjs.4352. PMID: 14515284
Stringer MD
Semin Pediatr Surg 2000 Nov;9(4):196-208. doi: 10.1053/spsu.2000.18844. PMID: 11112837

Prognosis

Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663
Griborio-Guzman AG, Aseyev OI, Shah H, Sadreddini M
Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547
Weinschenk RC, Wang WL, Lewis VO
J Am Acad Orthop Surg 2021 Jul 1;29(13):553-562. doi: 10.5435/JAAOS-D-20-01188. PMID: 33595238
Olson NJ, Linos K
Arch Pathol Lab Med 2018 Jun;142(6):761-766. doi: 10.5858/arpa.2016-0570-RS. PMID: 29848035
Fan M, Skupski DW
J Perinat Med 2014 May;42(3):273-9. doi: 10.1515/jpm-2013-0170. PMID: 24334427

Clinical prediction guides

Gültekin SE, Büttner R
Pathologie (Heidelb) 2022 Aug;43(Suppl 1):86-93. Epub 2022 Nov 8 doi: 10.1007/s00292-022-01150-9. PMID: 36346463
da Silva Leonel ACL, Dos Santos ST, de Amorim Carvalho EJ, de Castro JFL, de Almeida OP, da Cruz Perez DE
Head Neck Pathol 2021 Dec;15(4):1253-1260. Epub 2021 Aug 10 doi: 10.1007/s12105-021-01371-z. PMID: 34378165Free PMC Article
Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089
Olson NJ, Linos K
Arch Pathol Lab Med 2018 Jun;142(6):761-766. doi: 10.5858/arpa.2016-0570-RS. PMID: 29848035
Simionescu C, Mărgăritescu C, Stepan A, Ciurea R, Cernea N
Rom J Morphol Embryol 2011;52(3):743-58. PMID: 21892515

Recent systematic reviews

Severino-Lazo RJG, de Vasconcelos Carvalho M, Campello CP, Moraes SLD, do Egito Vasconcelos BC, Pellizzer EP
Head Neck Pathol 2023 Dec;17(4):1000-1010. Epub 2023 Dec 6 doi: 10.1007/s12105-023-01601-6. PMID: 38057461Free PMC Article
Rendina D, Abate V, Cacace G, D'Elia L, De Filippo G, Del Vecchio S, Galletti F, Cuocolo A, Strazzullo P
J Clin Endocrinol Metab 2022 Jul 14;107(8):e3428-e3436. doi: 10.1210/clinem/dgac253. PMID: 35468192
Ferrari D, Bernardi D, Siboni S, Lazzari V, Asti E, Bonavina L
World J Surg 2021 Jan;45(1):225-234. Epub 2020 Oct 7 doi: 10.1007/s00268-020-05789-4. PMID: 33026474Free PMC Article
Bologna-Molina R, Pereira-Prado V, Sánchez-Romero C, González-González R, Mosqueda-Taylor A
Med Oral Patol Oral Cir Bucal 2020 May 1;25(3):e388-e394. doi: 10.4317/medoral.23432. PMID: 32040459Free PMC Article
Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188

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