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Benign Pilar-Associated Mesenchyme Neoplasm

MedGen UID:
312919
•Concept ID:
C1706925
•
Neoplastic Process
Synonym: Benign Pilar-Associated Mesenchyme Tumor

Definition

A mesenchymal neoplasm arising from the pilar sheath of the hair follicle. It is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include fibrofolliculoma, perifollicular fibroma, pilar leiomyoma, and trichogenic myxoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Pilar-Associated Mesenchyme Neoplasm

Professional guidelines

PubMed

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Plast Reconstr Surg 2023 Jan 1;151(1):20e-30e. Epub 2022 Oct 4 doi: 10.1097/PRS.0000000000009780. PMID: 36194076Free PMC Article
Cardiac myxomas: clinical presentation, diagnosis and management.
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Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547
Overview of primary adult retroperitoneal tumours.
Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897

Recent clinical studies

Etiology

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Chondrosarcoma.
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Pathology of meningiomas.
Solomon DA, Pekmezci M
Handb Clin Neurol 2020;169:87-99. doi: 10.1016/B978-0-12-804280-9.00005-6. PMID: 32553300
Uterine fibroids in menopause and perimenopause.
Ulin M, Ali M, Chaudhry ZT, Al-Hendy A, Yang Q
Menopause 2020 Feb;27(2):238-242. doi: 10.1097/GME.0000000000001438. PMID: 31834160Free PMC Article
Cartilage-forming tumors.
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178

Diagnosis

Gene fusions in superficial mesenchymal neoplasms: Emerging entities and useful diagnostic adjuncts.
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Semin Diagn Pathol 2023 Jul;40(4):246-257. Epub 2023 Apr 25 doi: 10.1053/j.semdp.2023.04.014. PMID: 37156707
Ameloblastic Fibro-Odontoma.
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Mesenchymal tumors of the prostate.
McKenney JK
Mod Pathol 2018 Jan;31(S1):S133-142. doi: 10.1038/modpathol.2017.155. PMID: 29297486
Atypical Fibroxanthoma Revisited.
Mentzel T, Requena L, Brenn T
Surg Pathol Clin 2017 Jun;10(2):319-335. Epub 2017 Mar 14 doi: 10.1016/j.path.2017.01.007. PMID: 28477883
Glomus tumor.
Gombos Z, Zhang PJ
Arch Pathol Lab Med 2008 Sep;132(9):1448-52. doi: 10.5858/2008-132-1448-GT. PMID: 18788860

Therapy

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Gastrointestinal stromal tumour.
Joensuu H, Hohenberger P, Corless CL
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Gastrointestinal stromal tumours.
Connolly EM, Gaffney E, Reynolds JV
Br J Surg 2003 Oct;90(10):1178-86. doi: 10.1002/bjs.4352. PMID: 14515284

Prognosis

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Intramuscular Eyelid Myxoma.
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Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547
Chondrosarcoma.
Weinschenk RC, Wang WL, Lewis VO
J Am Acad Orthop Surg 2021 Jul 1;29(13):553-562. doi: 10.5435/JAAOS-D-20-01188. PMID: 33595238
Placental chorioangioma: literature review.
Fan M, Skupski DW
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Clinical prediction guides

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Uterine pseudotumors.
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Recent systematic reviews

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Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188

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