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Chondroid hamartoma

MedGen UID:
313028
•Concept ID:
C1707390
•
Disease or Syndrome
Synonyms: Chondroid Hamartoma; chondroid hamartoma
 
Monarch Initiative: MONDO:0006146

Definition

A hamartoma that is characterized by the presence of chondroid elements. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChondroid hamartoma

Professional guidelines

PubMed

Pulmonary placental transmogrification: a difficult pattern in differential diagnosis of pulmonary hamartomas from a tertiary care hospital in Turkey.
Yaprak Bayrak B, Vural C, Yildiz K
J Cardiothorac Surg 2023 Apr 11;18(1):127. doi: 10.1186/s13019-023-02217-1. PMID: 37041644Free PMC Article

Recent clinical studies

Etiology

Giant pulmonary hamartoma causing acute right heart failure.
Joshi HM, Page RD
Ann Thorac Surg 2014 Jan;97(1):e21-2. doi: 10.1016/j.athoracsur.2013.07.099. PMID: 24384217
Pediatric tracheal and endobronchial tumors: an institutional experience.
Roby BB, Drehner D, Sidman JD
Arch Otolaryngol Head Neck Surg 2011 Sep;137(9):925-9. doi: 10.1001/archoto.2011.153. PMID: 21930983
Diffuse chondroid malformation of the lung: cases series of a hitherto undescribed congenital lung disease.
Reix P, Wanin S, Dijoud F, Brouard J, Epaud R, Pracros JP, Boccon-Gibod L, Bellon G
Pediatr Pulmonol 2010 Jul;45(7):667-73. doi: 10.1002/ppul.21239. PMID: 20575097
Rare tracheal chondroid hamartoma masquerading as asthma in a 14-year-old girl.
Nadrous HF, Allen MS, Wylam ME
Ann Allergy Asthma Immunol 2004 May;92(5):576-9. doi: 10.1016/S1081-1206(10)61767-X. PMID: 15191028
HMGI-C and HMGI(Y) immunoreactivity correlates with cytogenetic abnormalities in lipomas, pulmonary chondroid hamartomas, endometrial polyps, and uterine leiomyomas and is compatible with rearrangement of the HMGI-C and HMGI(Y) genes.
Tallini G, Vanni R, Manfioletti G, Kazmierczak B, Faa G, Pauwels P, Bullerdiek J, Giancotti V, Van Den Berghe H, Dal Cin P
Lab Invest 2000 Mar;80(3):359-69. doi: 10.1038/labinvest.3780040. PMID: 10744071

Diagnosis

Large mesenchymal cystic and chondroid pulmonary hamartoma mimicking lung cancer: Case report.
Ahn S, Lee H, Kang JK, Kim IS, Moon Y, Choi JS, Choi SY
J Cardiothorac Surg 2023 Oct 10;18(1):278. doi: 10.1186/s13019-023-02394-z. PMID: 37817244Free PMC Article
Pulmonary chondroid hamartoma with nontuberculous mycobacterial infection: two case reports.
Lee YC, Moon JC, Gang SJ, Park SY, Kim SR
Medicine (Baltimore) 2015 Apr;94(14):e689. doi: 10.1097/MD.0000000000000689. PMID: 25860214Free PMC Article
Endobronchial chondroid hamartoma in an infant.
Jain V, Goel P, Kumar D, Seith A, Sarkar C, Kabra S, Agarwala S
J Pediatr Surg 2009 Sep;44(9):e21-3. doi: 10.1016/j.jpedsurg.2009.06.011. PMID: 19735804
Omental lipoblastoma.
Koplin SA, Twohig MH, Lund DP, Hafez GR
Pathol Res Pract 2008;204(4):277-81. Epub 2008 Feb 13 doi: 10.1016/j.prp.2007.10.004. PMID: 18276084
Chondroid hamartoma presenting as a neonatal nasal mass.
Kim DW, Low W, Billman G, Wickersham J, Kearns D
Int J Pediatr Otorhinolaryngol 1999 Mar 15;47(3):253-9. doi: 10.1016/s0165-5876(98)00121-9. PMID: 10321780

Prognosis

Molecular profiling of human non-small cell lung cancer by single-cell RNA-seq.
Li Q, Wang R, Yang Z, Li W, Yang J, Wang Z, Bai H, Cui Y, Tian Y, Wu Z, Guo Y, Xu J, Wen L, He J, Tang F, Wang J
Genome Med 2022 Aug 13;14(1):87. doi: 10.1186/s13073-022-01089-9. PMID: 35962452Free PMC Article
Giant pulmonary hamartoma causing acute right heart failure.
Joshi HM, Page RD
Ann Thorac Surg 2014 Jan;97(1):e21-2. doi: 10.1016/j.athoracsur.2013.07.099. PMID: 24384217
Multiple central endobronchial chondroid hamartoma.
Kang MW, Han JH, Yu JH, Kim YH, Na MH, Yu JH, Lim SP, Lee Y, Kim JH, Kang DY, Kim JO
Ann Thorac Surg 2007 Feb;83(2):691-3. doi: 10.1016/j.athoracsur.2006.06.014. PMID: 17258021
Rare tracheal chondroid hamartoma masquerading as asthma in a 14-year-old girl.
Nadrous HF, Allen MS, Wylam ME
Ann Allergy Asthma Immunol 2004 May;92(5):576-9. doi: 10.1016/S1081-1206(10)61767-X. PMID: 15191028
Surgery of lung metastases in renal cell carcinoma.
Cozzoli A, Milano S, Cancarini G, Zanotelli T, Cosciani Cunico S
Br J Urol 1995 Apr;75(4):445-7. doi: 10.1111/j.1464-410x.1995.tb07262.x. PMID: 7788253

Clinical prediction guides

Rare tracheal chondroid hamartoma masquerading as asthma in a 14-year-old girl.
Nadrous HF, Allen MS, Wylam ME
Ann Allergy Asthma Immunol 2004 May;92(5):576-9. doi: 10.1016/S1081-1206(10)61767-X. PMID: 15191028
Fine needle aspiration biopsy cytology of primary and metastatic pulmonary tumors.
Pilotti S, Rilke F, Gribaudi G, Damascelli B
Acta Cytol 1982 Sep-Oct;26(5):661-6. PMID: 6959455

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