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Intravasation

MedGen UID:
313320
•Concept ID:
C1708558
•
Finding
SNOMED CT: Intravasation (431721000124108)

Definition

The entry of a cell or foreign substance into a blood or lymphatic vessel. This process is pertinent to the description of the entry of cancer cells into a vessel, and the initiation of metastasis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntravasation

Professional guidelines

PubMed

The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Tokarz P, Blasiak J
Acta Biochim Pol 2012;59(4):467-74. Epub 2012 Nov 21 PMID: 23173124
The significance of hysteroscopic treatment of congenital uterine malformations.
Colacurci N, De Franciscis P, Fornaro F, Fortunato N, Perino A
Reprod Biomed Online 2002;4 Suppl 3:52-4. doi: 10.1016/s1472-6483(12)60117-5. PMID: 12470566
Management of hysteroscopic surgery complications.
Morrison DM
AORN J 1999 Jan;69(1):194-7, 199-209; quiz 210, 213-5, 21. doi: 10.1016/s0001-2092(06)62769-5. PMID: 9932178

Recent clinical studies

Etiology

Molecular aspects of brain metastases in breast cancer.
Tomasik B, Bieńkowski M, Górska Z, Gutowska K, Kumięga P, Jassem J, Duchnowska R
Cancer Treat Rev 2023 Mar;114:102521. Epub 2023 Jan 27 doi: 10.1016/j.ctrv.2023.102521. PMID: 36736124
New insights into the neural network of the nongravid uterus.
Tanos V, Laidlaw J, Tanos P, Papadopoulou A
Adv Clin Exp Med 2022 Oct;31(10):1153-1162. doi: 10.17219/acem/149913. PMID: 35766895
Interplay between desmoglein2 and hypoxia controls metastasis in breast cancer.
Chang PH, Chen MC, Tsai YP, Tan GYT, Hsu PH, Jeng YM, Tsai YF, Yang MH, Hwang-Verslues WW
Proc Natl Acad Sci U S A 2021 Jan 19;118(3) doi: 10.1073/pnas.2014408118. PMID: 33431674Free PMC Article
Endothelial Cells in the Tumor Microenvironment.
Sobierajska K, Ciszewski WM, Sacewicz-Hofman I, Niewiarowska J
Adv Exp Med Biol 2020;1234:71-86. doi: 10.1007/978-3-030-37184-5_6. PMID: 32040856
Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.
Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH
Sci Transl Med 2017 Jul 5;9(397) doi: 10.1126/scitranslmed.aan0026. PMID: 28679654Free PMC Article

Diagnosis

The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
Pergolizzi M, Bizzozero L, Maione F, Maldi E, Isella C, Macagno M, Mariella E, Bardelli A, Medico E, Marchiò C, Serini G, Di Nicolantonio F, Bussolino F, Arese M
J Exp Clin Cancer Res 2022 Sep 2;41(1):266. doi: 10.1186/s13046-022-02465-4. PMID: 36056393Free PMC Article
New insights into the neural network of the nongravid uterus.
Tanos V, Laidlaw J, Tanos P, Papadopoulou A
Adv Clin Exp Med 2022 Oct;31(10):1153-1162. doi: 10.17219/acem/149913. PMID: 35766895
An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression.
Scheidmann MC, Castro-Giner F, Strittmatter K, Krol I, Paasinen-Sohns A, Scherrer R, Donato C, Gkountela S, Szczerba BM, Diamantopoulou Z, Muenst S, Vlajnic T, Kunz L, Vetter M, Rochlitz C, Taylor V, Giachino C, Schroeder T, Platt RJ, Aceto N
Cancer Res 2022 Feb 15;82(4):681-694. doi: 10.1158/0008-5472.CAN-21-3908. PMID: 34916221Free PMC Article
The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets.
Wood SL, Pernemalm M, Crosbie PA, Whetton AD
Cancer Treat Rev 2014 May;40(4):558-66. Epub 2013 Oct 15 doi: 10.1016/j.ctrv.2013.10.001. PMID: 24176790
Mechanisms of metastasis.
Brodland DG, Zitelli JA
J Am Acad Dermatol 1992 Jul;27(1):1-8. doi: 10.1016/0190-9622(92)70146-7. PMID: 1619054

Therapy

Paradoxical effects of chemotherapy on tumor relapse and metastasis promotion.
D'Alterio C, Scala S, Sozzi G, Roz L, Bertolini G
Semin Cancer Biol 2020 Feb;60:351-361. Epub 2019 Aug 24 doi: 10.1016/j.semcancer.2019.08.019. PMID: 31454672
Paget's "Seed and Soil" Theory of Cancer Metastasis: An Idea Whose Time has Come.
Akhtar M, Haider A, Rashid S, Al-Nabet ADMH
Adv Anat Pathol 2019 Jan;26(1):69-74. doi: 10.1097/PAP.0000000000000219. PMID: 30339548
Targeting macrophages: therapeutic approaches in cancer.
Cassetta L, Pollard JW
Nat Rev Drug Discov 2018 Dec;17(12):887-904. Epub 2018 Oct 26 doi: 10.1038/nrd.2018.169. PMID: 30361552
Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.
Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH
Sci Transl Med 2017 Jul 5;9(397) doi: 10.1126/scitranslmed.aan0026. PMID: 28679654Free PMC Article
Cancer metastasis - tricks of the trade.
Zeeshan R, Mutahir Z
Bosn J Basic Med Sci 2017 Aug 20;17(3):172-182. doi: 10.17305/bjbms.2017.1908. PMID: 28278128Free PMC Article

Prognosis

EMT-cancer cells-derived exosomal miR-27b-3p promotes circulating tumour cells-mediated metastasis by modulating vascular permeability in colorectal cancer.
Dou R, Liu K, Yang C, Zheng J, Shi D, Lin X, Wei C, Zhang C, Fang Y, Huang S, Song J, Wang S, Xiong B
Clin Transl Med 2021 Dec;11(12):e595. doi: 10.1002/ctm2.595. PMID: 34936736Free PMC Article
Regulation of breast cancer metastasis signaling by miRNAs.
Petri BJ, Klinge CM
Cancer Metastasis Rev 2020 Sep;39(3):837-886. doi: 10.1007/s10555-020-09905-7. PMID: 32577859Free PMC Article
Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression.
Ren J, Smid M, Iaria J, Salvatori DCF, van Dam H, Zhu HJ, Martens JWM, Ten Dijke P
Breast Cancer Res 2019 Sep 18;21(1):109. doi: 10.1186/s13058-019-1194-0. PMID: 31533776Free PMC Article
Targeting macrophages: therapeutic approaches in cancer.
Cassetta L, Pollard JW
Nat Rev Drug Discov 2018 Dec;17(12):887-904. Epub 2018 Oct 26 doi: 10.1038/nrd.2018.169. PMID: 30361552
Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.
Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH
Sci Transl Med 2017 Jul 5;9(397) doi: 10.1126/scitranslmed.aan0026. PMID: 28679654Free PMC Article

Clinical prediction guides

The metastatic spread of breast cancer accelerates during sleep.
Diamantopoulou Z, Castro-Giner F, Schwab FD, Foerster C, Saini M, Budinjas S, Strittmatter K, Krol I, Seifert B, Heinzelmann-Schwarz V, Kurzeder C, Rochlitz C, Vetter M, Weber WP, Aceto N
Nature 2022 Jul;607(7917):156-162. Epub 2022 Jun 22 doi: 10.1038/s41586-022-04875-y. PMID: 35732738
Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells.
Donato C, Kunz L, Castro-Giner F, Paasinen-Sohns A, Strittmatter K, Szczerba BM, Scherrer R, Di Maggio N, Heusermann W, Biehlmaier O, Beisel C, Vetter M, Rochlitz C, Weber WP, Banfi A, Schroeder T, Aceto N
Cell Rep 2020 Sep 8;32(10):108105. doi: 10.1016/j.celrep.2020.108105. PMID: 32905777Free PMC Article
Tumor endothelial cells accelerate tumor metastasis.
Maishi N, Hida K
Cancer Sci 2017 Oct;108(10):1921-1926. Epub 2017 Aug 17 doi: 10.1111/cas.13336. PMID: 28763139Free PMC Article
Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.
Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH
Sci Transl Med 2017 Jul 5;9(397) doi: 10.1126/scitranslmed.aan0026. PMID: 28679654Free PMC Article
Endothelial Notch1 Activity Facilitates Metastasis.
Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A
Cancer Cell 2017 Mar 13;31(3):355-367. Epub 2017 Feb 23 doi: 10.1016/j.ccell.2017.01.007. PMID: 28238683

Recent systematic reviews

Safety of oil-based contrast medium for hysterosalpingography: a systematic review.
Roest I, Rosielle K, van Welie N, Dreyer K, Bongers M, Mijatovic V, Mol BW, Koks C
Reprod Biomed Online 2021 Jun;42(6):1119-1129. Epub 2021 Mar 23 doi: 10.1016/j.rbmo.2021.03.014. PMID: 33931367
Tubal flushing for subfertility.
Wang R, Watson A, Johnson N, Cheung K, Fitzgerald C, Mol BWJ, Mohiyiddeen L
Cochrane Database Syst Rev 2020 Oct 15;10(10):CD003718. doi: 10.1002/14651858.CD003718.pub5. PMID: 33053612Free PMC Article
Effectiveness on fertility outcome of tubal flushing with different contrast media: systematic review and network meta-analysis.
Wang R, van Welie N, van Rijswijk J, Johnson NP, Norman RJ, Dreyer K, Mijatovic V, Mol BW
Ultrasound Obstet Gynecol 2019 Aug;54(2):172-181. Epub 2019 Jun 26 doi: 10.1002/uog.20238. PMID: 30740799
Tubal flushing for subfertility.
Johnson N, Vandekerckhove P, Watson A, Lilford R, Harada T, Hughes E
Cochrane Database Syst Rev 2005 Apr 18;(2):CD003718. doi: 10.1002/14651858.CD003718.pub2. PMID: 15846676
Tubal flushing for subfertility.
Johnson N, Vandekerckhove P, Watson A, Lilford R, Harada T, Hughes E
Cochrane Database Syst Rev 2002;(3):CD003718. doi: 10.1002/14651858.CD003718. PMID: 12137708

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