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Laryngeal Lymphoepithelial Carcinoma

MedGen UID:
313340
Concept ID:
C1708653
Neoplastic Process
Synonyms: Laryngeal Lymphoepithelioma; Laryngeal Undifferentiated Carcinoma of the Nasopharyngeal Type

Definition

A rare and aggressive carcinoma that arises from the larynx. It is characterized by the presence of an undifferentiated carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLaryngeal Lymphoepithelial Carcinoma

Professional guidelines

PubMed

López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287

Recent clinical studies

Etiology

Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Hatta C, Terada T, Okita J, Kakibuchi M, Kubota A, Sakagami M
Auris Nasus Larynx 2003 Aug;30(3):273-7. doi: 10.1016/s0385-8146(03)00096-8. PMID: 12927291

Diagnosis

Acuña G, Gomà M, Temprana-Salvador J, Garcia-Bragado F, Alós L, Ordi J, Cardesa A, Nadal A
Mod Pathol 2019 May;32(5):621-626. Epub 2018 Dec 14 doi: 10.1038/s41379-018-0188-2. PMID: 30552415
Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903
López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Ferlito A, Weiss LM, Rinaldo A, Carbone A, Devaney KO, MacMillan C, Barnes L
Ann Otol Rhinol Laryngol 1997 May;106(5):437-44. doi: 10.1177/000348949710600514. PMID: 9153110

Therapy

Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903
Marsot-Dupuch K, Quillard J, Meyohas MC
Eur Radiol 2004 Mar;14 Suppl 3:E155-67. doi: 10.1007/s00330-003-2045-y. PMID: 14749957

Prognosis

Karki D, Kamboj M, Pasricha S, Mandal G, Yadav V, Arora V
J Cancer Res Ther 2024 Jan 1;20(1):445-449. Epub 2023 Apr 8 doi: 10.4103/jcrt.jcrt_1559_22. PMID: 38554360
Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
Galletti C, Pizzimenti C, Cavallari V, Galletti B
BMJ Case Rep 2021 Jul 20;14(7) doi: 10.1136/bcr-2020-241460. PMID: 34285018Free PMC Article
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Ferlito A, Weiss LM, Rinaldo A, Carbone A, Devaney KO, MacMillan C, Barnes L
Ann Otol Rhinol Laryngol 1997 May;106(5):437-44. doi: 10.1177/000348949710600514. PMID: 9153110

Clinical prediction guides

Acuña G, Gomà M, Temprana-Salvador J, Garcia-Bragado F, Alós L, Ordi J, Cardesa A, Nadal A
Mod Pathol 2019 May;32(5):621-626. Epub 2018 Dec 14 doi: 10.1038/s41379-018-0188-2. PMID: 30552415
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Yang HJ, Cho YJ, Kim HS, Chang MS, Sung MW, Kim WH
Head Neck 2001 Aug;23(8):629-36. doi: 10.1002/hed.1089. PMID: 11443745

Recent systematic reviews

Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877

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