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Skin Cavernous Hemangioma

MedGen UID:
313709
•Concept ID:
C1710105
•
Neoplastic Process
Synonyms: Cavernous angioma of skin; Cavernous hemangioma of skin; Cavernous nevus of skin
SNOMED CT: Cavernous angioma of skin (445305001); Cavernous nevus of skin (445305001); Cavernous hemangioma of skin (445305001)

Definition

A cavernous hemangioma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Cavernous Hemangioma

Professional guidelines

PubMed

Gastrointestinal Infantile Hemangioma: Presentation and Management.
Soukoulis IW, Liang MG, Fox VL, Mulliken JB, Alomari AI, Fishman SJ
J Pediatr Gastroenterol Nutr 2015 Oct;61(4):415-20. doi: 10.1097/MPG.0000000000000812. PMID: 25859824
Diagnosis and management of extensive vascular malformations of the lower limb: part I. Clinical diagnosis.
Redondo P, Aguado L, Martínez-Cuesta A
J Am Acad Dermatol 2011 Nov;65(5):893-906; quiz 907-8. doi: 10.1016/j.jaad.2010.12.047. PMID: 22000870
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997

Recent clinical studies

Etiology

Systemic and CNS manifestations of inherited cerebrovascular malformations.
Hart BL, Mabray MC, Morrison L, Whitehead KJ, Kim H
Clin Imaging 2021 Jul;75:55-66. Epub 2021 Jan 20 doi: 10.1016/j.clinimag.2021.01.020. PMID: 33493737Free PMC Article
Vertebral and spinal cavernous angiomas associated with familial cerebral cavernous malformation.
Toldo I, Drigo P, Mammi I, Marini V, Carollo C
Surg Neurol 2009 Feb;71(2):167-71. Epub 2008 Jan 22 doi: 10.1016/j.surneu.2007.07.067. PMID: 18207546
IPL technology: a review.
Raulin C, Greve B, Grema H
Lasers Surg Med 2003;32(2):78-87. doi: 10.1002/lsm.10145. PMID: 12561039
Cutaneous vascular proliferation. Part II. Hyperplasias and benign neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1997 Dec;37(6):887-919; quiz 920-2. doi: 10.1016/s0190-9622(97)70065-3. PMID: 9418757
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Diagnosis

Systemic and CNS manifestations of inherited cerebrovascular malformations.
Hart BL, Mabray MC, Morrison L, Whitehead KJ, Kim H
Clin Imaging 2021 Jul;75:55-66. Epub 2021 Jan 20 doi: 10.1016/j.clinimag.2021.01.020. PMID: 33493737Free PMC Article
Nasal Septal Cavernous Hemangioma.
Baki A
J Craniofac Surg 2018 Mar;29(2):e135-e136. doi: 10.1097/SCS.0000000000004220. PMID: 29215446
Diagnosis and management of extensive vascular malformations of the lower limb: part I. Clinical diagnosis.
Redondo P, Aguado L, Martínez-Cuesta A
J Am Acad Dermatol 2011 Nov;65(5):893-906; quiz 907-8. doi: 10.1016/j.jaad.2010.12.047. PMID: 22000870
Cavernous adrenal hemangioma.
Sabanegh E Jr, Harris MJ, Grider D
Urology 1993 Sep;42(3):327-30. doi: 10.1016/0090-4295(93)90626-l. PMID: 8379036
Hemangiomas in Nigeria.
Ofodile FA, Oluwasanmi JO
J Natl Med Assoc 1980 May;72(5):505-8. PMID: 7381956Free PMC Article

Therapy

IPL technology: a review.
Raulin C, Greve B, Grema H
Lasers Surg Med 2003;32(2):78-87. doi: 10.1002/lsm.10145. PMID: 12561039
Pathogenesis and treatment of infant skin strawberry hemangiomas: clinical and in vitro studies of hormonal effects.
Sasaki GH, Pang CY, Wittliff JL
Plast Reconstr Surg 1984 Mar;73(3):359-70. doi: 10.1097/00006534-198403000-00003. PMID: 6701212
Hemangiomas and vascular malformations.
Wisnicki JL
Ann Plast Surg 1984 Jan;12(1):41-59. doi: 10.1097/00000637-198401000-00007. PMID: 6367602
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997
Methotrexate in dermatology.
Burrows D, Shanks RG, Stevenson CJ
Br J Dermatol 1968 May;80(5):348-52. doi: 10.1111/j.1365-2133.1968.tb12317.x. PMID: 4873079

Prognosis

Multiple cavernous hemangiomas of the lung and liver mimicking metastasis: A case report and literature review.
Zhuang BW, Li W, Chen ZF, Cao CJ, Xie XY, Xie XH
Medicine (Baltimore) 2018 Dec;97(51):e13509. doi: 10.1097/MD.0000000000013509. PMID: 30572451Free PMC Article
Review of familial cerebral cavernous malformations and report of seven additional families.
de Vos IJ, Vreeburg M, Koek GH, van Steensel MA
Am J Med Genet A 2017 Feb;173(2):338-351. Epub 2016 Oct 28 doi: 10.1002/ajmg.a.38028. PMID: 27792856
Urethral hemangioma: case report and review of the literature.
Regragui S, Slaoui A, Karmouni T, El Khader K, Koutani A, Attya AI
Pan Afr Med J 2016;23:96. Epub 2016 Mar 15 doi: 10.11604/pamj.2016.23.96.8700. PMID: 27231506Free PMC Article
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Clinical prediction guides

A cavernous hemangioma of infundibulopelvic vessels presenting as an adnexal tumor: A rare case report and literature review.
Ma H, Tang H, Chen Q, Zheng W, Tan X
Medicine (Baltimore) 2022 Aug 19;101(33):e30113. doi: 10.1097/MD.0000000000030113. PMID: 35984186Free PMC Article
Rare case of vascular malformations in both skin and brain: Case report and published work review.
Oka M, Sakaguchi M, Fukumoto T, Seki SI, Nishigori C
J Dermatol 2017 Jul;44(7):813-817. Epub 2017 Mar 7 doi: 10.1111/1346-8138.13799. PMID: 28266042
An unusual case of cavernous hemangioma of the rib in a young man with lung tuberculosis: a brief review and case report.
Oruc M, Atay AE, Karabulut P, Pasa S, Elbey A, Ekin N, Yildirim S
Intern Med 2013;52(11):1263-5. doi: 10.2169/internalmedicine.52.9212. PMID: 23728568
Arteriovenous malformations and other vascular malformation syndromes.
Whitehead KJ, Smith MC, Li DY
Cold Spring Harb Perspect Med 2013 Feb 1;3(2):a006635. doi: 10.1101/cshperspect.a006635. PMID: 23125071Free PMC Article
Expression of smoothelin and smooth muscle actin in the skin.
Aneiros-Fernández J, Husein-ElAhmed H, Arias-Santiago S, Campos A, Carriel V, Sánchez-Montesinos I, Garcia del Moral R, Sánchez G, O'Valle F, Aneiros J
Histol Histopathol 2011 Jun;26(6):673-8. doi: 10.14670/HH-26.673. PMID: 21472682

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