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Sinonasal Oncocytic Papilloma

MedGen UID:
316467
•Concept ID:
C1704453
•
Neoplastic Process
Synonyms: Oncocytic Schneiderian Papilloma; Sinonasal Oncocytic Schneiderian Papilloma

Definition

A benign neoplasm with exophytic and endophytic growth arising from the lateral nasal wall or the paranasal sinuses. It is characterized by the proliferation of columnar cells with oncocytic features. Microcysts containing mucin and neutrophils are present in the epithelium. Clinical manifestations include nasal obstruction and epistaxis. Occasionally, it is associated with the development or presence of a carcinoma, usually squamous cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Oncocytic Papilloma

Professional guidelines

PubMed

Identification of Rare and Common HPV Genotypes in Sinonasal Papillomas.
Vor der Holte AP, Fangk I, Glombitza S, Wilkens L, Welkoborsky HJ
Head Neck Pathol 2020 Dec;14(4):936-943. Epub 2020 Apr 11 doi: 10.1007/s12105-020-01148-w. PMID: 32279179Free PMC Article

Recent clinical studies

Etiology

Outcomes of sinonasal oncocytic papilloma by endoscopic approach in 69 patients.
Wang H, Liu Q, Xu R, Zhang H, Zhai C, Sun X, Yu H, Wang D
Auris Nasus Larynx 2022 Feb;49(1):77-83. Epub 2021 Jun 11 doi: 10.1016/j.anl.2021.05.008. PMID: 34127313
Low prevalence of human papillomavirus infection in sinonasal inverted papilloma and oncocytic papilloma.
Wang H, Zhai C, Liu J, Wang J, Sun X, Hu L, Wang D
Virchows Arch 2020 Apr;476(4):577-583. Epub 2019 Dec 3 doi: 10.1007/s00428-019-02717-3. PMID: 31797088
MR imaging and CT features of oncocytic papilloma of the sinonasal tract with comparison to inverted papilloma.
Yang B, Li J, Dong J
Br J Radiol 2018 Oct;91(1090):20170957. Epub 2018 Sep 12 doi: 10.1259/bjr.20170957. PMID: 29987980Free PMC Article

Diagnosis

MR imaging and CT features of oncocytic papilloma of the sinonasal tract with comparison to inverted papilloma.
Yang B, Li J, Dong J
Br J Radiol 2018 Oct;91(1090):20170957. Epub 2018 Sep 12 doi: 10.1259/bjr.20170957. PMID: 29987980Free PMC Article

Therapy

MR imaging and CT features of oncocytic papilloma of the sinonasal tract with comparison to inverted papilloma.
Yang B, Li J, Dong J
Br J Radiol 2018 Oct;91(1090):20170957. Epub 2018 Sep 12 doi: 10.1259/bjr.20170957. PMID: 29987980Free PMC Article

Prognosis

Outcomes of sinonasal oncocytic papilloma by endoscopic approach in 69 patients.
Wang H, Liu Q, Xu R, Zhang H, Zhai C, Sun X, Yu H, Wang D
Auris Nasus Larynx 2022 Feb;49(1):77-83. Epub 2021 Jun 11 doi: 10.1016/j.anl.2021.05.008. PMID: 34127313

Clinical prediction guides

Outcomes of sinonasal oncocytic papilloma by endoscopic approach in 69 patients.
Wang H, Liu Q, Xu R, Zhang H, Zhai C, Sun X, Yu H, Wang D
Auris Nasus Larynx 2022 Feb;49(1):77-83. Epub 2021 Jun 11 doi: 10.1016/j.anl.2021.05.008. PMID: 34127313

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