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Colorectal carcinoma(CRC)

MedGen UID:
3170
Concept ID:
C0009402
Neoplastic Process
Synonyms: Cancer, Colorectal; Cancers, Colorectal; Carcinoma, Colorectal; Carcinomas, Colorectal; Colorectal Cancer; Colorectal Cancers; Colorectal Carcinoma; Colorectal Carcinomas
 
Monarch Initiative: MONDO:0024331
OMIM®: 114500; 172411; 191170; 516000; 516004; 516020; 516030; 516040

Definition

A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Park JH, Kim JH
Clin Mol Hepatol 2019 Mar;25(1):12-20. Epub 2018 Oct 5 doi: 10.3350/cmh.2018.0067. PMID: 30300991Free PMC Article
Axelrad JE, Lichtiger S, Yajnik V
World J Gastroenterol 2016 May 28;22(20):4794-801. doi: 10.3748/wjg.v22.i20.4794. PMID: 27239106Free PMC Article
Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology
Gut 2011 Oct;60(10):1309-16. Epub 2011 May 11 doi: 10.1136/gut.2010.228874. PMID: 21561874

Curated

DailyMed Drug Label, Capecitabine, 2021

Recent clinical studies

Etiology

Bell PD, Pai RK
Histopathology 2022 Dec;81(6):696-714. Epub 2022 Jul 15 doi: 10.1111/his.14713. PMID: 35758208
Niederreiter L, Adolph TE, Tilg H
Dig Liver Dis 2018 Jul;50(7):647-652. Epub 2018 Apr 3 doi: 10.1016/j.dld.2018.03.030. PMID: 29705028
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Hatoum HA, Abi Saad GS, Otrock ZK, Barada KA, Shamseddine AI
Int J Clin Oncol 2011 Jun;16(3):203-9. Epub 2010 Nov 11 doi: 10.1007/s10147-010-0140-z. PMID: 21069550
Bülow S, Svendsen LB, Mellemgaard A
Br J Surg 1990 May;77(5):502-5. doi: 10.1002/bjs.1800770509. PMID: 2354331

Diagnosis

Beech C, Hechtman JF
Surg Pathol Clin 2021 Sep;14(3):429-441. doi: 10.1016/j.path.2021.05.007. PMID: 34373094
Hissong E, Pittman ME
Crit Rev Clin Lab Sci 2020 Jan;57(1):22-36. Epub 2019 Oct 11 doi: 10.1080/10408363.2019.1670614. PMID: 31603697
Bhalla A, Zulfiqar M, Bluth MH
Clin Lab Med 2018 Jun;38(2):311-342. doi: 10.1016/j.cll.2018.02.008. PMID: 29776633
Harrison S, Benziger H
Surgeon 2011 Aug;9(4):200-10. Epub 2011 May 24 doi: 10.1016/j.surge.2011.01.011. PMID: 21672660
Alterescu KB
Nurs Clin North Am 1987 Jun;22(2):281-9. PMID: 3646660

Therapy

Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, Lu L, Jia HL, Dong QZ, Chen JH, Lu M, Qin LX
Theranostics 2021;11(13):6560-6572. Epub 2021 Apr 27 doi: 10.7150/thno.55609. PMID: 33995676Free PMC Article
Yang G, Zheng RY, Jin ZS
J Cancer Res Clin Oncol 2019 Dec;145(12):2891-2899. Epub 2019 Oct 15 doi: 10.1007/s00432-019-03053-4. PMID: 31617076Free PMC Article
Grauers Wiktorin H, Nilsson MS, Kiffin R, Sander FE, Lenox B, Rydström A, Hellstrand K, Martner A
Cancer Immunol Immunother 2019 Feb;68(2):163-174. Epub 2018 Oct 12 doi: 10.1007/s00262-018-2253-6. PMID: 30315349Free PMC Article
Mody K, Baldeo C, Bekaii-Saab T
Cancer J 2018 Jul/Aug;24(4):165-170. doi: 10.1097/PPO.0000000000000328. PMID: 30119079
Petrelli F, Ardito R, Ghidini A, Zaniboni A, Ghidini M, Barni S, Tomasello G
Oncology 2018;94(4):191-199. Epub 2018 Jan 23 doi: 10.1159/000486338. PMID: 29393280

Prognosis

Mathey MD, Pennella CL, Zubizarreta P
Arch Argent Pediatr 2021 Oct;119(5):e487-e498. doi: 10.5546/aap.2021.eng.e487. PMID: 34569749
Zhu L, Ling C, Xu T, Zhang J, Zhang Y, Liu Y, Fang C, Yang L, Zhuang W, Wang R, Ping J, Wang M
Pathol Oncol Res 2021;27:1609800. Epub 2021 Jul 2 doi: 10.3389/pore.2021.1609800. PMID: 34276258Free PMC Article
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Halle M, Schoenberg MH
Dtsch Arztebl Int 2009 Oct;106(44):722-7. Epub 2009 Oct 30 doi: 10.3238/arztebl.2009.0722. PMID: 19997551Free PMC Article
Bülow S, Svendsen LB, Mellemgaard A
Br J Surg 1990 May;77(5):502-5. doi: 10.1002/bjs.1800770509. PMID: 2354331

Clinical prediction guides

Bell PD, Pai RK
Histopathology 2022 Dec;81(6):696-714. Epub 2022 Jul 15 doi: 10.1111/his.14713. PMID: 35758208
Ritterhouse LL, Barletta JA
Semin Diagn Pathol 2015 Sep;32(5):400-8. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2015.02.010. PMID: 25744437
Shia J
Semin Diagn Pathol 2015 Sep;32(5):352-61. Epub 2015 Feb 4 doi: 10.1053/j.semdp.2015.02.018. PMID: 25716099Free PMC Article
Lam AK, Chan SS, Leung M
World J Gastroenterol 2014 Jun 14;20(22):6815-20. doi: 10.3748/wjg.v20.i22.6815. PMID: 24944471Free PMC Article
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
J Pathol 2014 Jan;232(2):199-209. doi: 10.1002/path.4287. PMID: 24122236Free PMC Article

Recent systematic reviews

Falz R, Bischoff C, Thieme R, Lässing J, Mehdorn M, Stelzner S, Busse M, Gockel I
J Cancer Res Clin Oncol 2022 Sep;148(9):2187-2213. Epub 2022 Jun 13 doi: 10.1007/s00432-022-04088-w. PMID: 35695931Free PMC Article
Balhareth A, Aldossary MY, McNamara D
World J Surg Oncol 2019 Aug 31;17(1):153. doi: 10.1186/s12957-019-1697-2. PMID: 31472677Free PMC Article
Nikolaou S, Qiu S, Fiorentino F, Rasheed S, Tekkis P, Kontovounisios C
Tech Coloproctol 2018 Jul;22(7):481-498. Epub 2018 Jul 18 doi: 10.1007/s10151-018-1820-3. PMID: 30022330Free PMC Article
Petrelli F, Ardito R, Ghidini A, Zaniboni A, Ghidini M, Barni S, Tomasello G
Oncology 2018;94(4):191-199. Epub 2018 Jan 23 doi: 10.1159/000486338. PMID: 29393280
Pyo JS, Sohn JH, Kang G
Hum Pathol 2016 Jul;53:91-6. Epub 2016 Mar 19 doi: 10.1016/j.humpath.2016.02.018. PMID: 27001432

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