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Pleural Lymphoma

MedGen UID:
318032
•Concept ID:
C1709575
•
Neoplastic Process
Synonym: Primary Pleural Lymphoma

Definition

A rare extranodal lymphoma that arises from the pleura with no evidence of involvement of other sites at the time of diagnosis. This category includes primary effusion lymphoma and pyothorax-associated lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPleural Lymphoma

Professional guidelines

PubMed

Malignant Pleural Effusion and Its Current Management: A Review.
Skok K, Hladnik G, Grm A, Crnjac A
Medicina (Kaunas) 2019 Aug 15;55(8) doi: 10.3390/medicina55080490. PMID: 31443309Free PMC Article
Primary effusion lymphoma: current concepts and management.
Arora N, Gupta A, Sadeghi N
Curr Opin Pulm Med 2017 Jul;23(4):365-370. doi: 10.1097/MCP.0000000000000384. PMID: 28399009
Pleural Effusion in Dasatinib-Treated Patients With Chronic Myeloid Leukemia in Chronic Phase: Identification and Management.
Cortes JE, Jimenez CA, Mauro MJ, Geyer A, Pinilla-Ibarz J, Smith BD
Clin Lymphoma Myeloma Leuk 2017 Feb;17(2):78-82. Epub 2016 Sep 17 doi: 10.1016/j.clml.2016.09.012. PMID: 28082112

Recent clinical studies

Etiology

Report of a Non-Hodgkin lymphoma case presenting with pleural effusion.
Akbayram S, Dogan M, Akgun C, Erbey F, Taşkin GA, Peker E, Oner AF
J Pediatr Hematol Oncol 2011 Jul;33(5):e192-4. doi: 10.1097/MPH.0b013e3181f4689d. PMID: 21423047
Primary pleural lymphoma: plaque-like thickening of the pleura.
Oikonomou A, Giatromanolaki A, Margaritis D, Froudarakis M, Prassopoulos P
Jpn J Radiol 2010 Jan;28(1):62-5. Epub 2010 Jan 30 doi: 10.1007/s11604-009-0377-5. PMID: 20112096
Pyothorax-associated lymphoma.
Aozasa K
Int J Hematol 1996 Dec;65(1):9-16. doi: 10.1016/s0925-5710(96)00532-4. PMID: 8990621
Primary cardiac lymphoma. No evidence for an etiologic association with Epstein-Barr virus.
Ito M, Nakagawa A, Tsuzuki T, Yokoi T, Yamashita Y, Asai J
Arch Pathol Lab Med 1996 Jun;120(6):555-9. PMID: 8651857
Artificial pneumothorax as a risk factor for development of pleural lymphoma.
Aozasa K, Ohsawa M, Iuchi K, Tajima K, Komatsu H, Shimoyama M
Jpn J Cancer Res 1993 Jan;84(1):55-7. doi: 10.1111/j.1349-7006.1993.tb02784.x. PMID: 8449828Free PMC Article

Diagnosis

Pleural lymphoma combined with pleural sarcoidosis.
Tashiro H, Takahashi K, Komiya N, Miyahara N, Hiratsuka M, Okamoto S, Kido S, Kimura S, Sueoka-Aragane N
Respir Investig 2023 Nov;61(6):698-701. Epub 2023 Sep 15 doi: 10.1016/j.resinv.2023.07.010. PMID: 37708635
The Sandwich Sign in Pleural Lymphoma.
Hassan M, Taylor L, Daneshvar C
Arch Bronconeumol (Engl Ed) 2021 Apr;57(4):302. Epub 2020 Sep 24 doi: 10.1016/j.arbres.2020.07.041. PMID: 32980164
Primary Pleural Lymphoma.
Fernandes FR, Oliveira RC, Rodrigues LV
Arch Bronconeumol (Engl Ed) 2018 Aug;54(8):430. Epub 2017 Dec 26 doi: 10.1016/j.arbres.2017.10.002. PMID: 29287613
Pleural Lymphoma.
Choy CF, Lee S
J Bronchology Interv Pulmonol 2016 Apr;23(2):146-8. doi: 10.1097/LBR.0000000000000270. PMID: 27058717
B cell lymphoma with lung involvement: what is it about?
Mian M, Wasle I, Gritsch S, Willenbacher W, Fiegl M
Acta Haematol 2015;133(2):221-5. Epub 2014 Nov 4 doi: 10.1159/000365778. PMID: 25376208

Therapy

A case report on the effect of rituximab on pyothorax-associated lymphoma.
Wang F, Lan H
Medicine (Baltimore) 2019 Dec;98(50):e18393. doi: 10.1097/MD.0000000000018393. PMID: 31852157Free PMC Article
The pleural sandwich sign in two cases of primary pleural lymphoma.
Kim Y, Lee M, Ryu YJ, Cho MS
Korean J Radiol 2015 Jan-Feb;16(1):213-6. Epub 2015 Jan 9 doi: 10.3348/kjr.2015.16.1.213. PMID: 25598693Free PMC Article
B cell lymphoma with lung involvement: what is it about?
Mian M, Wasle I, Gritsch S, Willenbacher W, Fiegl M
Acta Haematol 2015;133(2):221-5. Epub 2014 Nov 4 doi: 10.1159/000365778. PMID: 25376208
Pyothorax-associated lymphoma.
Aozasa K
Int J Hematol 1996 Dec;65(1):9-16. doi: 10.1016/s0925-5710(96)00532-4. PMID: 8990621
Primary Epstein-Barr virus-related non-Hodgkin's lymphoma of the pleural cavity following long-standing tuberculous empyema.
Molinie V, Pouchot J, Navratil E, Aubert F, Vinceneux P, Barge J
Arch Pathol Lab Med 1996 Mar;120(3):288-91. PMID: 8629908

Prognosis

Primary pleural lymphoma: plaque-like thickening of the pleura.
Oikonomou A, Giatromanolaki A, Margaritis D, Froudarakis M, Prassopoulos P
Jpn J Radiol 2010 Jan;28(1):62-5. Epub 2010 Jan 30 doi: 10.1007/s11604-009-0377-5. PMID: 20112096
Primary pleural lymphoma: an unusual presentation of childhood non-Hodgkin lymphoma.
Karadeniz C, Güven MA, Ruacan S, Demirbilek S, Sağbil S, Akhan O
Pediatr Hematol Oncol 2000 Dec;17(8):695-9. doi: 10.1080/08880010050211411. PMID: 11127402
Pyothorax-associated pleural lymphoma. A case evolving from T-cell-rich lymphoid infiltration to overt B-cell lymphoma in association with Epstein-Barr virus.
Ibuka T, Fukayama M, Hayashi Y, Funata N, Koike M, Ikeda T, Mizutani S
Cancer 1994 Feb 1;73(3):738-44. doi: 10.1002/1097-0142(19940201)73:3<738::aid-cncr2820730339>3.0.co;2-6. PMID: 8299098
Prognostic factors for pleural lymphoma patients.
Aozasa K, Ohsawa M, Iuchi K, Mori T, Komatsu H, Tajima K, Minato K, Tajima K, Shimoyama M
Jpn J Clin Oncol 1991 Dec;21(6):417-21. PMID: 1805046

Clinical prediction guides

Pyothorax-associated pleural lymphoma. A case evolving from T-cell-rich lymphoid infiltration to overt B-cell lymphoma in association with Epstein-Barr virus.
Ibuka T, Fukayama M, Hayashi Y, Funata N, Koike M, Ikeda T, Mizutani S
Cancer 1994 Feb 1;73(3):738-44. doi: 10.1002/1097-0142(19940201)73:3<738::aid-cncr2820730339>3.0.co;2-6. PMID: 8299098
Prognostic factors for pleural lymphoma patients.
Aozasa K, Ohsawa M, Iuchi K, Mori T, Komatsu H, Tajima K, Minato K, Tajima K, Shimoyama M
Jpn J Clin Oncol 1991 Dec;21(6):417-21. PMID: 1805046

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