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Sporadic Thyroid Gland Medullary Carcinoma

MedGen UID:
318194
Concept ID:
C1710166
Neoplastic Process

Definition

A non-hereditary medullary carcinoma of the thyroid gland not associated with multiple endocrine neoplasia. The majority of thyroid gland medullary carcinomas are sporadic. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSporadic Thyroid Gland Medullary Carcinoma

Professional guidelines

PubMed

Wells SA Jr
Endocr Relat Cancer 2018 Feb;25(2):T1-T13. Epub 2017 Nov 15 doi: 10.1530/ERC-17-0325. PMID: 29142004Free PMC Article
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Brunt LM, Wells SA Jr
Surg Clin North Am 1987 Apr;67(2):263-79. doi: 10.1016/s0039-6109(16)44183-6. PMID: 2882613

Recent clinical studies

Etiology

Diwaker C, Sarathi V, Jaiswal SK, Shah R, Deshmukh A, Thomas AE, Prakash G, Malhotra G, Patil V, Lila A, Shah N, Bandgar T
Fam Cancer 2021 Jul;20(3):241-251. Epub 2021 Jan 4 doi: 10.1007/s10689-020-00219-9. PMID: 33392850
Aubert S, Berdelou A, Gnemmi V, Behal H, Caiazzo R, D'herbomez M, Pigny P, Wemeau JL, Carnaille B, Renaud F, Bouchindhomme B, Leteurtre E, Perrais M, Pattou F, Do Cao C
Virchows Arch 2018 Mar;472(3):461-468. Epub 2018 Feb 1 doi: 10.1007/s00428-018-2303-7. PMID: 29388012
Essig GF Jr, Porter K, Schneider D, Arpaia D, Lindsey SC, Busonero G, Fineberg D, Fruci B, Boelaert K, Smit JW, Meijer JA, Duntas LH, Sharma N, Costante G, Filetti S, Sippel RS, Biondi B, Topliss DJ, Pacini F, Maciel RM, Walz PC, Kloos RT
Thyroid 2016 Nov;26(11):1563-1572. Epub 2016 Oct 11 doi: 10.1089/thy.2016.0255. PMID: 27604949Free PMC Article
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Nosé V
Endocr Pathol 2008 Winter;19(4):226-40. doi: 10.1007/s12022-008-9045-z. PMID: 18931957

Diagnosis

Thomas CM, Asa SL, Ezzat S, Sawka AM, Goldstein D
Curr Oncol 2019 Oct;26(5):338-344. Epub 2019 Oct 1 doi: 10.3747/co.26.5539. PMID: 31708652Free PMC Article
Iacobone M, Citton M, Viel G, Schiavone D, Torresan F
Updates Surg 2017 Jun;69(2):181-191. Epub 2017 Apr 28 doi: 10.1007/s13304-017-0451-y. PMID: 28455835
Schmid KW
Recent Results Cancer Res 2015;204:41-60. doi: 10.1007/978-3-319-22542-5_2. PMID: 26494383
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Gimm O
Cancer Lett 2001 Feb 26;163(2):143-56. doi: 10.1016/s0304-3835(00)00697-2. PMID: 11165748

Therapy

Vitale G, Dicitore A, Messina E, Sciammarella C, Faggiano A, Colao A
Recent Pat Anticancer Drug Discov 2016;11(3):275-82. doi: 10.2174/1574892811666160614115356. PMID: 27306881
Spitzweg C, Morris JC, Bible KC
Endocr Relat Cancer 2016 Jun;23(6):R287-97. Epub 2016 May 16 doi: 10.1530/ERC-16-0104. PMID: 27185870
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Ye L, Santarpia L, Gagel RF
Endocr Pract 2009 Sep-Oct;15(6):597-604. doi: 10.4158/EP09148.RAR. PMID: 19546050
Gimm O
Cancer Lett 2001 Feb 26;163(2):143-56. doi: 10.1016/s0304-3835(00)00697-2. PMID: 11165748

Prognosis

Yadav M, Agrawal V, Pani KC, Verma R, Jaiswal S, Mishra A, Pandey R
Indian J Pathol Microbiol 2018 Oct-Dec;61(4):485-488. doi: 10.4103/IJPM.IJPM_478_17. PMID: 30303134
Spitzweg C, Morris JC, Bible KC
Endocr Relat Cancer 2016 Jun;23(6):R287-97. Epub 2016 May 16 doi: 10.1530/ERC-16-0104. PMID: 27185870
Brauckhoff M, Lorenz K, Ukkat J, Brauckhoff K, Gimm O, Dralle H
Scand J Surg 2004;93(4):249-60. doi: 10.1177/145749690409300402. PMID: 15658665
Gimm O
Cancer Lett 2001 Feb 26;163(2):143-56. doi: 10.1016/s0304-3835(00)00697-2. PMID: 11165748
Emmertsen K
Dan Med Bull 1985 Mar;32(1):1-28. PMID: 2859145

Clinical prediction guides

Machens A, Kaatzsch P, Lorenz K, Horn LC, Wickenhauser C, Schmid KW, Dralle H, Siebolts U
Surgery 2022 Feb;171(2):360-367. Epub 2021 Oct 1 doi: 10.1016/j.surg.2021.07.035. PMID: 34602296
Gemignani F, Romei C, Ciampi R, Corrado A, Melaiu O, Figlioli G, Bonotti A, Foddis R, Cristaudo A, Pellegrini G, Vivaldi A, Cipollini M, Landi S, Elisei R
Thyroid 2020 Nov;30(11):1579-1588. Epub 2020 May 5 doi: 10.1089/thy.2019.0352. PMID: 32228166
Ye F, Gao H, Xiao L, Zuo Z, Liu Y, Zhao Q, Chen H, Feng W, Fu B, Sun L, Jiang X, He D, Jiang H, Yang M, Li L, Chen F, Liu X, Li S, Li Z, Jiang Y, Cheng L, Bu H
Int J Cancer 2019 Mar 15;144(6):1321-1330. Epub 2018 Sep 24 doi: 10.1002/ijc.31825. PMID: 30132833
Aubert S, Berdelou A, Gnemmi V, Behal H, Caiazzo R, D'herbomez M, Pigny P, Wemeau JL, Carnaille B, Renaud F, Bouchindhomme B, Leteurtre E, Perrais M, Pattou F, Do Cao C
Virchows Arch 2018 Mar;472(3):461-468. Epub 2018 Feb 1 doi: 10.1007/s00428-018-2303-7. PMID: 29388012
Spitzweg C, Morris JC, Bible KC
Endocr Relat Cancer 2016 Jun;23(6):R287-97. Epub 2016 May 16 doi: 10.1530/ERC-16-0104. PMID: 27185870

Recent systematic reviews

Del Gobbo A, Peverelli E, Treppiedi D, Lania A, Mantovani G, Ferrero S
Exp Cell Res 2016 Aug 1;346(1):85-90. Epub 2016 Jun 16 doi: 10.1016/j.yexcr.2016.06.004. PMID: 27321957
Vitale G, Dicitore A, Messina E, Sciammarella C, Faggiano A, Colao A
Recent Pat Anticancer Drug Discov 2016;11(3):275-82. doi: 10.2174/1574892811666160614115356. PMID: 27306881

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