A subjective feeling of tiredness characterized by a lack of energy and motivation.

Absence of menses for an interval of time equivalent to a total of more than (or equal to) 3 previous cycles or 6 months.

Underdevelopment of the uterus.

A foot where the longitudinal arch of the foot is in contact with the ground or floor when the individual is standing; or, in a patient lying supine, a foot where the arch is in contact with the surface of a flat board pressed against the sole of the foot by the examiner with a pressure similar to that expected from weight bearing; or, the height of the arch is reduced.

Digits that appear disproportionately short compared to the hand/foot. The word brachydactyly is used here to describe a series distinct patterns of shortened digits (brachydactyly types A-E). This is the sense used here.

The legs angle inward, such that the knees are close together and the ankles far apart.

Dissolution or degeneration of bone tissue of the phalanges of the hand.

Diminished length of one or more metacarpal bones in relation to the others of the same hand or to the contralateral metacarpal.

A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms).

Abnormally increased frequency (usually defined as three or more) loose or watery bowel movements a day.

Impaired ability to absorb one or more nutrients from the intestine.

Sudden and involuntary contractions of one or more muscles.

Diminished length of a metatarsal bone, with resultant proximal displacement of the associated toe.

Abnormal increase in muscle size and mass not due to training.

Abnormality originating in one or more muscles, i.e., of the set of muscles of body.

A noncongenital process of hair loss, which may progress to partial or complete baldness.

Alopecia areata is a common disorder that causes hair loss. "Alopecia" is a Latin term that means baldness, and "areata" refers to the patchy nature of the hair loss that is typically seen with this condition.\n\nIn most people with alopecia areata, hair falls out in small, round patches, leaving coin-sized areas of bare skin. This patchy hair loss occurs most often on the scalp but can affect other parts of the body as well. Uncommonly, the hair loss involves the entire scalp (in which case the condition is known as alopecia totalis) or the whole body (alopecia universalis). Other rare forms of alopecia areata, which have different patterns of hair loss, have also been reported.\n\nAlopecia areata affects people of all ages, although it most commonly appears in adolescence or early adulthood. Hair loss occurs over a period of weeks. The hair usually grows back after several months, although it may fall out again. In some cases, unpredictable cycles of hair loss followed by regrowth can last for years. In addition to hair loss, some affected individuals have fingernail and toenail abnormalities, such as pits on the surface of the nails.\n\nThe hair loss associated with alopecia areata is not painful or disabling. However, it causes changes in a person's appearance that can profoundly affect quality of life and self-esteem. In some people, the condition can lead to depression, anxiety, and other emotional or psychological issues.