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Otitis media, susceptibility to(OMS)

MedGen UID:
318936
•Concept ID:
C1833692
•
Finding
Synonyms: COME/ROM; OMS; OTITIS MEDIA, CHRONIC/RECURRENT
 
Gene (location): A2ML1 (12p13.31)
 
Monarch Initiative: MONDO:0008162
OMIM®: 166760

Clinical features

From HPO
Recurrent otitis media
MedGen UID:
155436
•Concept ID:
C0747085
•
Disease or Syndrome
Increased susceptibility to otitis media, as manifested by recurrent episodes of otitis media.
See: Feature record | Search on this feature

Professional guidelines

PubMed

Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update.
Hayashi T, Kitamura K, Hashimoto S, Hotomi M, Kojima H, Kudo F, Maruyama Y, Sawada S, Taiji H, Takahashi G, Takahashi H, Uno Y, Yano H
Auris Nasus Larynx 2020 Aug;47(4):493-526. Epub 2020 Jun 20 doi: 10.1016/j.anl.2020.05.019. PMID: 32576390
Clinical Practice Guideline: Otitis Media with Effusion (Update).
Rosenfeld RM, Shin JJ, Schwartz SR, Coggins R, Gagnon L, Hackell JM, Hoelting D, Hunter LL, Kummer AW, Payne SC, Poe DS, Veling M, Vila PM, Walsh SA, Corrigan MD
Otolaryngol Head Neck Surg 2016 Feb;154(1 Suppl):S1-S41. doi: 10.1177/0194599815623467. PMID: 26832942
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article

Recent clinical studies

Etiology

Primary ciliary dyskinesia in the genomics age.
Lucas JS, Davis SD, Omran H, Shoemark A
Lancet Respir Med 2020 Feb;8(2):202-216. Epub 2019 Oct 14 doi: 10.1016/S2213-2600(19)30374-1. PMID: 31624012
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.
Tian C, Hromatka BS, Kiefer AK, Eriksson N, Noble SM, Tung JY, Hinds DA
Nat Commun 2017 Sep 19;8(1):599. doi: 10.1038/s41467-017-00257-5. PMID: 28928442Free PMC Article
Clinical Practice Guideline: Otitis Media with Effusion (Update).
Rosenfeld RM, Shin JJ, Schwartz SR, Coggins R, Gagnon L, Hackell JM, Hoelting D, Hunter LL, Kummer AW, Payne SC, Poe DS, Veling M, Vila PM, Walsh SA, Corrigan MD
Otolaryngol Head Neck Surg 2016 Feb;154(1 Suppl):S1-S41. doi: 10.1177/0194599815623467. PMID: 26832942
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article
The Health Belief Model: a decade later.
Janz NK, Becker MH
Health Educ Q 1984 Spring;11(1):1-47. doi: 10.1177/109019818401100101. PMID: 6392204

Diagnosis

Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update.
Hayashi T, Kitamura K, Hashimoto S, Hotomi M, Kojima H, Kudo F, Maruyama Y, Sawada S, Taiji H, Takahashi G, Takahashi H, Uno Y, Yano H
Auris Nasus Larynx 2020 Aug;47(4):493-526. Epub 2020 Jun 20 doi: 10.1016/j.anl.2020.05.019. PMID: 32576390
Primary ciliary dyskinesia in the genomics age.
Lucas JS, Davis SD, Omran H, Shoemark A
Lancet Respir Med 2020 Feb;8(2):202-216. Epub 2019 Oct 14 doi: 10.1016/S2213-2600(19)30374-1. PMID: 31624012
Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review.
Jamee M, Moniri S, Zaki-Dizaji M, Olbrich P, Yazdani R, Jadidi-Niaragh F, Aghamahdi F, Abolhassani H, Condliffe AM, Aghamohammadi A, Azizi G
Clin Rev Allergy Immunol 2020 Dec;59(3):323-333. doi: 10.1007/s12016-019-08738-9. PMID: 31111319
Clinical Practice Guideline: Otitis Media with Effusion (Update).
Rosenfeld RM, Shin JJ, Schwartz SR, Coggins R, Gagnon L, Hackell JM, Hoelting D, Hunter LL, Kummer AW, Payne SC, Poe DS, Veling M, Vila PM, Walsh SA, Corrigan MD
Otolaryngol Head Neck Surg 2016 Feb;154(1 Suppl):S1-S41. doi: 10.1177/0194599815623467. PMID: 26832942
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article

Therapy

Cefditoren: a clinical overview.
Giuliano S, Acquasanta A, Martini L, Sbrana F, Flammini S, Tascini C
New Microbiol 2023 Feb;46(1):9-17. PMID: 36853812
Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update.
Hayashi T, Kitamura K, Hashimoto S, Hotomi M, Kojima H, Kudo F, Maruyama Y, Sawada S, Taiji H, Takahashi G, Takahashi H, Uno Y, Yano H
Auris Nasus Larynx 2020 Aug;47(4):493-526. Epub 2020 Jun 20 doi: 10.1016/j.anl.2020.05.019. PMID: 32576390
Clinical Practice Guideline: Otitis Media with Effusion (Update).
Rosenfeld RM, Shin JJ, Schwartz SR, Coggins R, Gagnon L, Hackell JM, Hoelting D, Hunter LL, Kummer AW, Payne SC, Poe DS, Veling M, Vila PM, Walsh SA, Corrigan MD
Otolaryngol Head Neck Surg 2016 Feb;154(1 Suppl):S1-S41. doi: 10.1177/0194599815623467. PMID: 26832942
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article
The Health Belief Model: a decade later.
Janz NK, Becker MH
Health Educ Q 1984 Spring;11(1):1-47. doi: 10.1177/109019818401100101. PMID: 6392204

Prognosis

Window of Susceptibility to Acute Otitis Media Infection.
Bajorski P, Fuji N, Kaur R, Pichichero ME
Pediatrics 2023 Feb 1;151(2) doi: 10.1542/peds.2022-058556. PMID: 36618001Free PMC Article
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article
Otitis media.
Pichichero ME, Casey JR
Expert Opin Pharmacother 2002 Aug;3(8):1073-90. doi: 10.1517/14656566.3.8.1073. PMID: 12150687
Otitis media.
Gupta BD, Singh A
Indian J Pediatr 2001 Jul;68 Suppl 3:S24-31. PMID: 11980456

Clinical prediction guides

Window of Susceptibility to Acute Otitis Media Infection.
Bajorski P, Fuji N, Kaur R, Pichichero ME
Pediatrics 2023 Feb 1;151(2) doi: 10.1542/peds.2022-058556. PMID: 36618001Free PMC Article
Pneumonia, Sinusitis, Influenza and Other Respiratory Illnesses in Acute Otitis Media-Prone Children.
Pichichero ME, Chapman TJ, Bajorski P
Pediatr Infect Dis J 2021 Nov 1;40(11):975-980. doi: 10.1097/INF.0000000000003228. PMID: 34382614Free PMC Article
Bacterial otitis media in sub-Saharan Africa: a systematic review and meta-analysis.
Tesfa T, Mitiku H, Sisay M, Weldegebreal F, Ataro Z, Motbaynor B, Marami D, Teklemariam Z
BMC Infect Dis 2020 Mar 17;20(1):225. doi: 10.1186/s12879-020-4950-y. PMID: 32183752Free PMC Article
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, Craig WA; Sinus And Allergy Health Partnership
Otolaryngol Head Neck Surg 2004 Jan;130(1 Suppl):1-45. doi: 10.1016/j.otohns.2003.12.003. PMID: 14726904Free PMC Article
What is an 'otitis-prone' child?
Alho OP, Koivu M, Sorri M
Int J Pediatr Otorhinolaryngol 1991 May;21(3):201-9. doi: 10.1016/0165-5876(91)90001-r. PMID: 1869373

Recent systematic reviews

Bacterial otitis media in sub-Saharan Africa: a systematic review and meta-analysis.
Tesfa T, Mitiku H, Sisay M, Weldegebreal F, Ataro Z, Motbaynor B, Marami D, Teklemariam Z
BMC Infect Dis 2020 Mar 17;20(1):225. doi: 10.1186/s12879-020-4950-y. PMID: 32183752Free PMC Article
Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review.
Jamee M, Moniri S, Zaki-Dizaji M, Olbrich P, Yazdani R, Jadidi-Niaragh F, Aghamahdi F, Abolhassani H, Condliffe AM, Aghamohammadi A, Azizi G
Clin Rev Allergy Immunol 2020 Dec;59(3):323-333. doi: 10.1007/s12016-019-08738-9. PMID: 31111319
Probiotics for preventing acute otitis media in children.
Scott AM, Clark J, Julien B, Islam F, Roos K, Grimwood K, Little P, Del Mar CB
Cochrane Database Syst Rev 2019 Jun 18;6(6):CD012941. doi: 10.1002/14651858.CD012941.pub2. PMID: 31210358Free PMC Article
Antimicrobial Resistant Streptococcus pneumoniae: Prevalence, Mechanisms, and Clinical Implications.
Cherazard R, Epstein M, Doan TL, Salim T, Bharti S, Smith MA
Am J Ther 2017 May;24(3):e361-e369. doi: 10.1097/MJT.0000000000000551. PMID: 28430673
Effects of nitrogen dioxide on human health: systematic review of experimental and epidemiological studies conducted between 2002 and 2006.
Latza U, Gerdes S, Baur X
Int J Hyg Environ Health 2009 May;212(3):271-87. Epub 2008 Sep 3 doi: 10.1016/j.ijheh.2008.06.003. PMID: 18771952

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    • ClinVar
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      Related information in NCBI Gene
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      Clinical tests in GTR
    • OMIM
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    • OMIM(Genes)
      OMIM records containing genes associated with phenotypes registered in MedGen
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