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Foodborne botulism

MedGen UID:
320728
•Concept ID:
C1739094
•
Disease or Syndrome
Synonyms: Botulism, Foodborne; Foodborne Botulism; Foodborne Botulisms
SNOMED CT: Foodborne botulism (398523009)
 
Monarch Initiative: MONDO:0016453
Orphanet: ORPHA228371

Definition

Foodborne botulism is the most common form of botulism (see this term), a rare acquired neuromuscular junction disease with descending flaccid paralysis due to botulinum neurotoxins (BoNTs). It is caused by consumption of contaminated food containing BoNTs. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFoodborne botulism
Follow this link to review classifications for Foodborne botulism in Orphanet.

Professional guidelines

PubMed

Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.
Rao AK, Sobel J, Chatham-Stephens K, Luquez C
MMWR Recomm Rep 2021 May 7;70(2):1-30. doi: 10.15585/mmwr.rr7002a1. PMID: 33956777Free PMC Article
Foodborne Botulism: Clinical Diagnosis and Medical Treatment.
Lonati D, Schicchi A, Crevani M, Buscaglia E, Scaravaggi G, Maida F, Cirronis M, Petrolini VM, Locatelli CA
Toxins (Basel) 2020 Aug 7;12(8) doi: 10.3390/toxins12080509. PMID: 32784744Free PMC Article
An outbreak of botulism in Thailand: clinical manifestations and management of severe respiratory failure.
Kongsaengdao S, Samintarapanya K, Rusmeechan S, Wongsa A, Pothirat C, Permpikul C, Pongpakdee S, Puavilai W, Kateruttanakul P, Phengtham U, Panjapornpon K, Janma J, Piyavechviratana K, Sithinamsuwan P, Deesomchok A, Tongyoo S, Vilaichone W, Boonyapisit K, Mayotarn S, Piya-Isragul B, Rattanaphon A, Intalapaporn P, Dusitanond P, Harnsomburana P, Laowittawas W, Chairangsaris P, Suwantamee J, Wongmek W, Ratanarat R, Poompichate A, Panyadilok H, Sutcharitchan N, Chuesuwan A, Oranrigsupau P, Sutthapas C, Tanprawate S, Lorsuwansiri J, Phattana N; Thai Botulism Study Group
Clin Infect Dis 2006 Nov 15;43(10):1247-56. Epub 2006 Oct 16 doi: 10.1086/508176. PMID: 17051488

Recent clinical studies

Etiology

Tracing Foodborne Botulism Events Caused by Clostridium botulinum in Xinjiang Province, China, Using a Core Genome Sequence Typing Scheme.
Ma X, Li K, Li F, Su J, Meng W, Sun Y, Sun H, Sun J, Yuan Y, Lin Y, Hu S, Xu X, He Z
Microbiol Spectr 2022 Dec 21;10(6):e0116422. Epub 2022 Nov 15 doi: 10.1128/spectrum.01164-22. PMID: 36377961Free PMC Article
Neurophysiological patterns of acute and post-acute foodborne botulism.
Boccagni C, Prestandrea C, D'Agostino T, Rubino F, Renda M, Sesti E, Bagnato S
Muscle Nerve 2021 Oct;64(4):435-444. Epub 2021 Jul 29 doi: 10.1002/mus.27370. PMID: 34255868
Foodborne botulism in Poland in 2017.
Czerwiński M, Czarkowski MP, Kondej B
Przegl Epidemiol 2019;73(4):445-450. doi: 10.32394/pe.73.42. PMID: 32237694
Foodborne botulism in Poland in 2016.
Czerwiński M, Czarkowski MP, Kondej B
Przegl Epidemiol 2018;72(2):149-155. PMID: 30111083
Foodborne botulism.
Hutchinson DN
BMJ 1992 Aug 1;305(6848):264-5. doi: 10.1136/bmj.305.6848.264. PMID: 1392853Free PMC Article

Diagnosis

Foodborne Botulism, Canada, 2006-2021(1).
Harris RA, Tchao C, Prystajecky N, Weedmark K, Tcholakov Y, Lefebvre M, Austin JW
Emerg Infect Dis 2023 Sep;29(9):1730-7. doi: 10.3201/eid2909.230409. PMID: 37610295Free PMC Article
Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.
Rao AK, Sobel J, Chatham-Stephens K, Luquez C
MMWR Recomm Rep 2021 May 7;70(2):1-30. doi: 10.15585/mmwr.rr7002a1. PMID: 33956777Free PMC Article
Foodborne Botulism: Clinical Diagnosis and Medical Treatment.
Lonati D, Schicchi A, Crevani M, Buscaglia E, Scaravaggi G, Maida F, Cirronis M, Petrolini VM, Locatelli CA
Toxins (Basel) 2020 Aug 7;12(8) doi: 10.3390/toxins12080509. PMID: 32784744Free PMC Article
Adult Intestinal Toxemia Botulism.
Harris RA, Anniballi F, Austin JW
Toxins (Basel) 2020 Jan 24;12(2) doi: 10.3390/toxins12020081. PMID: 31991691Free PMC Article
Botulism.
Sobel J
Clin Infect Dis 2005 Oct 15;41(8):1167-73. Epub 2005 Aug 29 doi: 10.1086/444507. PMID: 16163636

Therapy

Lambert-Eaton Myasthenic Syndrome, Botulism, and Immune Checkpoint Inhibitor-Related Myasthenia Gravis.
Guidon AC
Continuum (Minneap Minn) 2019 Dec;25(6):1785-1806. doi: 10.1212/CON.0000000000000807. PMID: 31794471
Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016.
O'Horo JC, Harper EP, El Rafei A, Ali R, DeSimone DC, Sakusic A, Abu Saleh OM, Marcelin JR, Tan EM, Rao AK, Sobel J, Tosh PK
Clin Infect Dis 2017 Dec 27;66(suppl_1):S43-S56. doi: 10.1093/cid/cix815. PMID: 29293927Free PMC Article
Botulism.
Sobel J
Clin Infect Dis 2005 Oct 15;41(8):1167-73. Epub 2005 Aug 29 doi: 10.1086/444507. PMID: 16163636
Nine cases of foodborne botulism type B in France and literature review.
Abgueguen P, Delbos V, Chennebault JM, Fanello S, Brenet O, Alquier P, Granry JC, Pichard E
Eur J Clin Microbiol Infect Dis 2003 Dec;22(12):749-52. Epub 2003 Nov 6 doi: 10.1007/s10096-003-1019-y. PMID: 14605938
Botulism in the United States: a clinical and epidemiologic review.
Shapiro RL, Hatheway C, Swerdlow DL
Ann Intern Med 1998 Aug 1;129(3):221-8. doi: 10.7326/0003-4819-129-3-199808010-00011. PMID: 9696731

Prognosis

Foodborne botulism in Poland in 2018-2021.
Czerwiński M, Czarkowski MP
Przegl Epidemiol 2023;77(2):233-240. doi: 10.32394/pe.77.22. PMID: 37860971
Neurophysiological patterns of acute and post-acute foodborne botulism.
Boccagni C, Prestandrea C, D'Agostino T, Rubino F, Renda M, Sesti E, Bagnato S
Muscle Nerve 2021 Oct;64(4):435-444. Epub 2021 Jul 29 doi: 10.1002/mus.27370. PMID: 34255868
Foodborne Botulism in Ukraine from 1955 to 2018.
Semenko N, Mokhort H, Sokolovska O, Kolesnikova I, Kuzin I, Saylors K
Foodborne Pathog Dis 2021 Apr;18(4):260-266. Epub 2020 Dec 17 doi: 10.1089/fpd.2020.2826. PMID: 33332209Free PMC Article
Foodborne botulism in Poland in 2016.
Czerwiński M, Czarkowski MP, Kondej B
Przegl Epidemiol 2018;72(2):149-155. PMID: 30111083
Botulism in the United States: a clinical and epidemiologic review.
Shapiro RL, Hatheway C, Swerdlow DL
Ann Intern Med 1998 Aug 1;129(3):221-8. doi: 10.7326/0003-4819-129-3-199808010-00011. PMID: 9696731

Clinical prediction guides

Foodborne botulism in Poland in 2018-2021.
Czerwiński M, Czarkowski MP
Przegl Epidemiol 2023;77(2):233-240. doi: 10.32394/pe.77.22. PMID: 37860971
Neurophysiological patterns of acute and post-acute foodborne botulism.
Boccagni C, Prestandrea C, D'Agostino T, Rubino F, Renda M, Sesti E, Bagnato S
Muscle Nerve 2021 Oct;64(4):435-444. Epub 2021 Jul 29 doi: 10.1002/mus.27370. PMID: 34255868
Foodborne Botulism in Ukraine from 1955 to 2018.
Semenko N, Mokhort H, Sokolovska O, Kolesnikova I, Kuzin I, Saylors K
Foodborne Pathog Dis 2021 Apr;18(4):260-266. Epub 2020 Dec 17 doi: 10.1089/fpd.2020.2826. PMID: 33332209Free PMC Article
Foodborne botulism in Poland in 2016.
Czerwiński M, Czarkowski MP, Kondej B
Przegl Epidemiol 2018;72(2):149-155. PMID: 30111083
An outbreak of botulism in Thailand: clinical manifestations and management of severe respiratory failure.
Kongsaengdao S, Samintarapanya K, Rusmeechan S, Wongsa A, Pothirat C, Permpikul C, Pongpakdee S, Puavilai W, Kateruttanakul P, Phengtham U, Panjapornpon K, Janma J, Piyavechviratana K, Sithinamsuwan P, Deesomchok A, Tongyoo S, Vilaichone W, Boonyapisit K, Mayotarn S, Piya-Isragul B, Rattanaphon A, Intalapaporn P, Dusitanond P, Harnsomburana P, Laowittawas W, Chairangsaris P, Suwantamee J, Wongmek W, Ratanarat R, Poompichate A, Panyadilok H, Sutcharitchan N, Chuesuwan A, Oranrigsupau P, Sutthapas C, Tanprawate S, Lorsuwansiri J, Phattana N; Thai Botulism Study Group
Clin Infect Dis 2006 Nov 15;43(10):1247-56. Epub 2006 Oct 16 doi: 10.1086/508176. PMID: 17051488

Recent systematic reviews

Foodborne botulism in Turkey, 1983 to 2017.
Karsen H, Ceylan MR, Bayındır H, Akdeniz H
Infect Dis (Lond) 2019 Feb;51(2):91-96. Epub 2019 Jan 21 doi: 10.1080/23744235.2018.1524582. PMID: 30663916
The Epidemiology of Foodborne Botulism Outbreaks: A Systematic Review.
Fleck-Derderian S, Shankar M, Rao AK, Chatham-Stephens K, Adjei S, Sobel J, Meltzer MI, Meaney-Delman D, Pillai SK
Clin Infect Dis 2017 Dec 27;66(suppl_1):S73-S81. doi: 10.1093/cid/cix846. PMID: 29293934
Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016.
O'Horo JC, Harper EP, El Rafei A, Ali R, DeSimone DC, Sakusic A, Abu Saleh OM, Marcelin JR, Tan EM, Rao AK, Sobel J, Tosh PK
Clin Infect Dis 2017 Dec 27;66(suppl_1):S43-S56. doi: 10.1093/cid/cix815. PMID: 29293927Free PMC Article
Clinical Features of Foodborne and Wound Botulism: A Systematic Review of the Literature, 1932-2015.
Chatham-Stephens K, Fleck-Derderian S, Johnson SD, Sobel J, Rao AK, Meaney-Delman D
Clin Infect Dis 2017 Dec 27;66(suppl_1):S11-S16. doi: 10.1093/cid/cix811. PMID: 29293923

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