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Muscular atrophy, malignant neurogenic

MedGen UID:
322469
•Concept ID:
C1834689
•
Disease or Syndrome
Synonym: Muscular Atrophy, Malignant Neurogenic
 
Monarch Initiative: MONDO:0008027
OMIM®: 158650

Clinical features

From HPO
Muscular atrophy
MedGen UID:
892680
•Concept ID:
C0541794
•
Pathologic Function
The presence of skeletal muscular atrophy (which is also known as amyotrophy).
See: Feature record | Search on this feature
Respiratory paralysis
MedGen UID:
19748
•Concept ID:
C0035232
•
Finding
Inability to move the muscles of respiration.
See: Feature record | Search on this feature
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Recent clinical studies

Etiology

Quantitative EMG of facial muscles in myasthenia patients with MuSK antibodies.
Farrugia ME, Kennett RP, Hilton-Jones D, Newsom-Davis J, Vincent A
Clin Neurophysiol 2007 Feb;118(2):269-77. Epub 2006 Dec 8 doi: 10.1016/j.clinph.2006.10.004. PMID: 17157556
Type-selective muscular degeneration promotes infiltrative growth of intramuscular lipoma.
Mori K, Chano T, Matsumoto K, Ishizawa M, Matsusue Y, Okabe H
BMC Musculoskelet Disord 2004 Jun 18;5:20. doi: 10.1186/1471-2474-5-20. PMID: 15202946Free PMC Article
Histopathology of different types of atrophy of the human tongue.
Bässler R
Pathol Res Pract 1987 Feb;182(1):87-97. doi: 10.1016/S0344-0338(87)80147-4. PMID: 3588408
Skeletal muscular atrophy in malignant tumour diseases: neurogenic or unspecific?
Schmitt HP
Acta Neuropathol 1979 Nov;48(2):149-52. doi: 10.1007/BF00691157. PMID: 506697
Neurogenic muscle involvement in myasthenia gravis. A clinical and histopathological study.
Oosterhuis H, Bethlem J
J Neurol Neurosurg Psychiatry 1973 Apr;36(2):244-54. doi: 10.1136/jnnp.36.2.244. PMID: 4708458Free PMC Article

Diagnosis

7T for clinical imaging of benign peripheral nerve tumors: preliminary results.
Amrami KK, Chebrolu VV, Felmlee JP, Frick MA, Powell GM, Marek T, Howe BM, Fagan AJ, Kollasch PD, Spinner RJ
Acta Neurochir (Wien) 2023 Nov;165(11):3549-3558. Epub 2023 Jul 19 doi: 10.1007/s00701-023-05724-1. PMID: 37464202
Is paravertebral muscles edema a consequence of neurogenic changes in MuSK-positive myasthenia gravis?
Bardakov SN, Tsargush VA, Carlier PG, Duc TM, Emelin AY, Polushin AY, Emelyantsev AA, Belskikh AN, Berezhnaya EN, Lapin SV, Moshnikova AN, Deev RV
Acta Myol 2022;41(4):178-187. Epub 2022 Dec 31 doi: 10.36185/2532-1900-082. PMID: 36793652Free PMC Article
Delayed postirradiation camptocormia.
Kelly L, Perju-Dumbrava LD, Thyagarajan D, Lee YC
BMJ Case Rep 2013 Aug 19;2013 doi: 10.1136/bcr-2013-200083. PMID: 23960150Free PMC Article
Quantitative EMG of facial muscles in myasthenia patients with MuSK antibodies.
Farrugia ME, Kennett RP, Hilton-Jones D, Newsom-Davis J, Vincent A
Clin Neurophysiol 2007 Feb;118(2):269-77. Epub 2006 Dec 8 doi: 10.1016/j.clinph.2006.10.004. PMID: 17157556
Neurogenic muscle involvement in myasthenia gravis. A clinical and histopathological study.
Oosterhuis H, Bethlem J
J Neurol Neurosurg Psychiatry 1973 Apr;36(2):244-54. doi: 10.1136/jnnp.36.2.244. PMID: 4708458Free PMC Article

Therapy

Neurogenic muscle atrophy in myasthenia gravis.
Brownell B, Oppenheimer DR, Spalding JM
J Neurol Neurosurg Psychiatry 1972 Jun;35(3):311-22. doi: 10.1136/jnnp.35.3.311. PMID: 4338443Free PMC Article

Prognosis

Is paravertebral muscles edema a consequence of neurogenic changes in MuSK-positive myasthenia gravis?
Bardakov SN, Tsargush VA, Carlier PG, Duc TM, Emelin AY, Polushin AY, Emelyantsev AA, Belskikh AN, Berezhnaya EN, Lapin SV, Moshnikova AN, Deev RV
Acta Myol 2022;41(4):178-187. Epub 2022 Dec 31 doi: 10.36185/2532-1900-082. PMID: 36793652Free PMC Article
Neuropathology in classical and variant ataxia-telangiectasia.
Verhagen MM, Martin JJ, van Deuren M, Ceuterick-de Groote C, Weemaes CM, Kremer BH, Taylor MA, Willemsen MA, Lammens M
Neuropathology 2012 Jun;32(3):234-44. Epub 2011 Oct 24 doi: 10.1111/j.1440-1789.2011.01263.x. PMID: 22017321
Quantitative EMG of facial muscles in myasthenia patients with MuSK antibodies.
Farrugia ME, Kennett RP, Hilton-Jones D, Newsom-Davis J, Vincent A
Clin Neurophysiol 2007 Feb;118(2):269-77. Epub 2006 Dec 8 doi: 10.1016/j.clinph.2006.10.004. PMID: 17157556
Lumbosacral perineural cysts as a cause for neurogenic muscular hypertrophy.
Amoiridis G, Wöhrle J, Heye N, Przuntek H
Electromyogr Clin Neurophysiol 1997 Aug;37(5):273-5. PMID: 9298339
Radioimmunoassay of serum myoglobin in neuromuscular diseases.
Askmark H, Osterman PO, Roxin LE, Venge P
J Neurol Neurosurg Psychiatry 1981 Jan;44(1):68-72. doi: 10.1136/jnnp.44.1.68. PMID: 7205308Free PMC Article

Clinical prediction guides

Muscle histopathology in myasthenia gravis with antibodies against MuSK and AChR.
Martignago S, Fanin M, Albertini E, Pegoraro E, Angelini C
Neuropathol Appl Neurobiol 2009 Feb;35(1):103-10. doi: 10.1111/j.1365-2990.2008.00965.x. PMID: 19187062
Quantitative EMG of facial muscles in myasthenia patients with MuSK antibodies.
Farrugia ME, Kennett RP, Hilton-Jones D, Newsom-Davis J, Vincent A
Clin Neurophysiol 2007 Feb;118(2):269-77. Epub 2006 Dec 8 doi: 10.1016/j.clinph.2006.10.004. PMID: 17157556
A study of sternocleidomastoid muscular atrophy after modified neck dissection.
Ohtawa T, Katagiri M, Harada T
Surg Today 1998;28(1):46-58. doi: 10.1007/BF02483608. PMID: 9505317
Skeletal muscular atrophy in malignant tumour diseases: neurogenic or unspecific?
Schmitt HP
Acta Neuropathol 1979 Nov;48(2):149-52. doi: 10.1007/BF00691157. PMID: 506697
Neurogenic muscle involvement in myasthenia gravis. A clinical and histopathological study.
Oosterhuis H, Bethlem J
J Neurol Neurosurg Psychiatry 1973 Apr;36(2):244-54. doi: 10.1136/jnnp.36.2.244. PMID: 4708458Free PMC Article

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