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Focal friction-related palmoplantar hyperkeratosis

MedGen UID:
Concept ID:
Synonym: Hyperkeratosis, palmoplantar, focal friction-related
HPO: HP:0007497


Hyperkeratosis affecting the palm of the hand and the sole of the foot in areas exposed to friction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal friction-related palmoplantar hyperkeratosis

Conditions with this feature

Focal palmoplantar and gingival keratoderma
MedGen UID:
Concept ID:
Disease or Syndrome
A very rare form of focal palmoplantar keratoderma with characteristics of painful circumscribed hyperkeratotic lesions on weight-bearing areas of soles, moderate focal hyperkeratosis of palmar pressure-related areas and an asymptomatic leukokeratosis confined to labial and lingual attached gingiva. Additional occasional features may include hyperhidrosis, follicular keratosis and extended oral mucosa involvement.

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