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Grade 5 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

MedGen UID:
324157
•Concept ID:
C1556386
•
Finding
Synonym: CTCAE Grade 5 Pharynx mucositis/stomatitis (clinical exam)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 5 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

Professional guidelines

PubMed

Validation of an instrument to measure the quality of life in children with oropharyngeal mucositis undergoing cancer treatment.
Gutiérrez-Vargas R, Velasco-Rojano E, Villasís-Keever MÁ, Portilla-Robertson J, Gutiérrez-Rodelo A, Flores-Navarro S, Juárez-Villegas LE, Zapata-Tarrés M
Bol Med Hosp Infant Mex 2019;76(1):35-43. doi: 10.24875/BMHIM.18000146. PMID: 30657465

Recent clinical studies

Etiology

Evaluation of purely accelerated six fractions per week radiotherapy in postoperative oral cavity squamous cell carcinoma.
Rath S, Khurana R, Sapru S, Rastogi M, Gandhi AK, Hadi R, Sahni K, Mishra SP, Srivastava AK, Syedkather F
Asia Pac J Clin Oncol 2020 Feb;16(1):14-22. Epub 2019 Dec 2 doi: 10.1111/ajco.13244. PMID: 31793206
Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants.
Nasuf AWA, Ojha S, Dorling J
Cochrane Database Syst Rev 2018 Sep 7;9(9):CD011921. doi: 10.1002/14651858.CD011921.pub2. PMID: 30191961Free PMC Article
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection.
Kuwabara T, Hiyama T, Oka S, Urabe Y, Tanaka S, Yoshihara M, Arihiro K, Shimamoto F, Chayama K
Gastrointest Endosc 2012 Dec;76(6):1095-103. Epub 2012 Sep 27 doi: 10.1016/j.gie.2012.07.032. PMID: 23022050
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Diagnosis

Diagnostic Value of Narrow Band Imaging in Visualization of Pathological Lesions in Larynx and Hypopharynx.
Šatanková J, Staníková L, Švejdová A, Černý M, Laco J, Chrobok V
Acta Medica (Hradec Kralove) 2021;64(1):22-28. doi: 10.14712/18059694.2021.4. PMID: 33855955
Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease.
Galli J, Settimi S, Salonna G, Mele DA, De Corso E, Paludetti G
Eur Arch Otorhinolaryngol 2020 Mar;277(3):819-825. Epub 2019 Dec 19 doi: 10.1007/s00405-019-05765-2. PMID: 31858222
Phonotherapeutic Intervention in Patients With Mucosal Leishmaniasis Sequelae.
Machado de Machado FC, Lessa MM, Cielo CA, Souza TMO, Prates de Souza FV, Ribeiro CS, Silva JA, Filho EMC, Machado PRL, Montagner T, Muniz MM, Barbosa TN, Gonçalves DDS, Cincurá C
J Voice 2020 Sep;34(5):720-731. Epub 2019 Feb 20 doi: 10.1016/j.jvoice.2018.12.015. PMID: 30795925
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585

Therapy

Evaluation of purely accelerated six fractions per week radiotherapy in postoperative oral cavity squamous cell carcinoma.
Rath S, Khurana R, Sapru S, Rastogi M, Gandhi AK, Hadi R, Sahni K, Mishra SP, Srivastava AK, Syedkather F
Asia Pac J Clin Oncol 2020 Feb;16(1):14-22. Epub 2019 Dec 2 doi: 10.1111/ajco.13244. PMID: 31793206
Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants.
Nasuf AWA, Ojha S, Dorling J
Cochrane Database Syst Rev 2018 Sep 7;9(9):CD011921. doi: 10.1002/14651858.CD011921.pub2. PMID: 30191961Free PMC Article
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Prognosis

Evaluation of purely accelerated six fractions per week radiotherapy in postoperative oral cavity squamous cell carcinoma.
Rath S, Khurana R, Sapru S, Rastogi M, Gandhi AK, Hadi R, Sahni K, Mishra SP, Srivastava AK, Syedkather F
Asia Pac J Clin Oncol 2020 Feb;16(1):14-22. Epub 2019 Dec 2 doi: 10.1111/ajco.13244. PMID: 31793206
Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants.
Nasuf AWA, Ojha S, Dorling J
Cochrane Database Syst Rev 2018 Sep 7;9(9):CD011921. doi: 10.1002/14651858.CD011921.pub2. PMID: 30191961Free PMC Article
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection.
Kuwabara T, Hiyama T, Oka S, Urabe Y, Tanaka S, Yoshihara M, Arihiro K, Shimamoto F, Chayama K
Gastrointest Endosc 2012 Dec;76(6):1095-103. Epub 2012 Sep 27 doi: 10.1016/j.gie.2012.07.032. PMID: 23022050
A new model for predicting acute mucosal toxicity in head-and-neck cancer patients undergoing radiotherapy with altered schedules.
Strigari L, Pedicini P, D'Andrea M, Pinnarò P, Marucci L, Giordano C, Benassi M
Int J Radiat Oncol Biol Phys 2012 Aug 1;83(5):e697-702. Epub 2012 May 10 doi: 10.1016/j.ijrobp.2012.02.004. PMID: 22578541
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Clinical prediction guides

Pharyngeal-sparing radiation for head and neck carcinoma of unknown primary following TORS assisted work-up.
Grewal AS, Rajasekaran K, Cannady SB, Chalian AA, Ghiam AF, Lin A, LiVolsi V, Lukens JN, Mitra N, Montone KT, Newman JG, O'Malley BW Jr,, Rassekh CH, Weinstein GS, Swisher-McClure S
Laryngoscope 2020 Mar;130(3):691-697. Epub 2019 Aug 14 doi: 10.1002/lary.28200. PMID: 31411747
Phonotherapeutic Intervention in Patients With Mucosal Leishmaniasis Sequelae.
Machado de Machado FC, Lessa MM, Cielo CA, Souza TMO, Prates de Souza FV, Ribeiro CS, Silva JA, Filho EMC, Machado PRL, Montagner T, Muniz MM, Barbosa TN, Gonçalves DDS, Cincurá C
J Voice 2020 Sep;34(5):720-731. Epub 2019 Feb 20 doi: 10.1016/j.jvoice.2018.12.015. PMID: 30795925
A new model for predicting acute mucosal toxicity in head-and-neck cancer patients undergoing radiotherapy with altered schedules.
Strigari L, Pedicini P, D'Andrea M, Pinnarò P, Marucci L, Giordano C, Benassi M
Int J Radiat Oncol Biol Phys 2012 Aug 1;83(5):e697-702. Epub 2012 May 10 doi: 10.1016/j.ijrobp.2012.02.004. PMID: 22578541
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Recent systematic reviews

Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants.
Nasuf AWA, Ojha S, Dorling J
Cochrane Database Syst Rev 2018 Sep 7;9(9):CD011921. doi: 10.1002/14651858.CD011921.pub2. PMID: 30191961Free PMC Article

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