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Elevated mean arterial pressure

MedGen UID:
326719
Concept ID:
C1840376
Finding
HPO: HP:0004972

Definition

An abnormal increase in the average blood pressure in an individual during a single cardiac cycle. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Elevated mean arterial pressure

Conditions with this feature

Essential hypertension
MedGen UID:
88442
Concept ID:
C0085580
Disease or Syndrome
The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution (Pickering, 1978). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait (Platt, 1963). McDonough et al. (1964) defended the monogenic idea. See McKusick (1960) and Kurtz and Spence (1993) for reviews. Swales (1985) reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.

Professional guidelines

PubMed

Bowers S, Franco E
Am Fam Physician 2020 Feb 1;101(3):159-166. PMID: 32003952
Benetos A, Petrovic M, Strandberg T
Circ Res 2019 Mar 29;124(7):1045-1060. doi: 10.1161/CIRCRESAHA.118.313236. PMID: 30920928
Kraut JA, Madias NE
Nat Rev Nephrol 2010 May;6(5):274-85. Epub 2010 Mar 23 doi: 10.1038/nrneph.2010.33. PMID: 20308999

Recent clinical studies

Etiology

Yi S, Ning L, Xiao H
Ren Fail 2023 Dec;45(1):2238828. doi: 10.1080/0886022X.2023.2238828. PMID: 37482910Free PMC Article
Ling HZ, Guy G, Nicolaides KH, Kametas NA
Am J Obstet Gynecol MFM 2023 Feb;5(2):100824. Epub 2022 Dec 1 doi: 10.1016/j.ajogmf.2022.100824. PMID: 36464241
Mushlin HM, Lessing N, Wessell AP, Chryssikos T, Pratt N, Caffes N, Oliver J, Aarabi B, Schwartzbauer G
World Neurosurg 2020 Dec;144:e405-e413. Epub 2020 Sep 2 doi: 10.1016/j.wneu.2020.08.163. PMID: 32889182
Davidson AJ, Ferencz SE, Sosnov JA, Howard JT, Janak JC, Chung KK, Stewart IJ
Burns 2018 Mar;44(2):298-304. Epub 2017 Aug 31 doi: 10.1016/j.burns.2017.07.023. PMID: 28864102
Conde-Agudelo A, Belizán JM, Lede R, Bergel EF
Am J Obstet Gynecol 1993 Sep;169(3):509-14. doi: 10.1016/0002-9378(93)90609-m. PMID: 8372853

Diagnosis

Ling HZ, Guy G, Nicolaides KH, Kametas NA
Am J Obstet Gynecol MFM 2023 Feb;5(2):100824. Epub 2022 Dec 1 doi: 10.1016/j.ajogmf.2022.100824. PMID: 36464241
Prisco SZ, Prokop JW, Sarkis AB, Yeo NC, Hoffman MJ, Hansen CC, Jacob HJ, Flister MJ, Lazar J
Hypertension 2014 Oct;64(4):883-90. Epub 2014 Jul 7 doi: 10.1161/HYPERTENSIONAHA.114.03550. PMID: 25001272Free PMC Article
Ances BM, Bhatt A, Vaida F, Rosario D, Alexander T, Marquie-Beck J, Ellis RJ, Letendre S, Grant I, McCutchan JA; HIV Neurobehavioral Research Center (HNRC) Group
J Neurovirol 2009 May;15(3):249-56. doi: 10.1080/13550280902962443. PMID: 19562611Free PMC Article
Conde-Agudelo A, Belizán JM, Lede R, Bergel EF
Am J Obstet Gynecol 1993 Sep;169(3):509-14. doi: 10.1016/0002-9378(93)90609-m. PMID: 8372853
Chesley LC, Sibai BM
Am J Obstet Gynecol 1988 Aug;159(2):275-9. doi: 10.1016/s0002-9378(88)80067-x. PMID: 3044108

Therapy

Carnevali L, Cerritelli F, Guolo F, Sgoifo A
J Manipulative Physiol Ther 2021 May;44(4):319-329. Epub 2021 Jan 9 doi: 10.1016/j.jmpt.2020.09.002. PMID: 33436300
Amaral LM, Cottrell JN, Comley KM, Cunningham MW Jr, Witcher A, Vaka VR, Ibrahim T, LaMarca B
Pregnancy Hypertens 2020 Oct;22:151-155. Epub 2020 Sep 11 doi: 10.1016/j.preghy.2020.09.002. PMID: 32980622Free PMC Article
Prisco SZ, Prokop JW, Sarkis AB, Yeo NC, Hoffman MJ, Hansen CC, Jacob HJ, Flister MJ, Lazar J
Hypertension 2014 Oct;64(4):883-90. Epub 2014 Jul 7 doi: 10.1161/HYPERTENSIONAHA.114.03550. PMID: 25001272Free PMC Article
Kiprono LV, Wallace K, Moseley J, Martin J Jr, Lamarca B
Am J Obstet Gynecol 2013 Jul;209(1):44.e1-6. Epub 2013 Mar 29 doi: 10.1016/j.ajog.2013.03.032. PMID: 23545163Free PMC Article
Conde-Agudelo A, Belizán JM, Lede R, Bergel EF
Am J Obstet Gynecol 1993 Sep;169(3):509-14. doi: 10.1016/0002-9378(93)90609-m. PMID: 8372853

Prognosis

Yi S, Ning L, Xiao H
Ren Fail 2023 Dec;45(1):2238828. doi: 10.1080/0886022X.2023.2238828. PMID: 37482910Free PMC Article
Mushlin HM, Lessing N, Wessell AP, Chryssikos T, Pratt N, Caffes N, Oliver J, Aarabi B, Schwartzbauer G
World Neurosurg 2020 Dec;144:e405-e413. Epub 2020 Sep 2 doi: 10.1016/j.wneu.2020.08.163. PMID: 32889182
Davidson AJ, Ferencz SE, Sosnov JA, Howard JT, Janak JC, Chung KK, Stewart IJ
Burns 2018 Mar;44(2):298-304. Epub 2017 Aug 31 doi: 10.1016/j.burns.2017.07.023. PMID: 28864102
Conde-Agudelo A, Belizán JM, Lede R, Bergel EF
Am J Obstet Gynecol 1993 Sep;169(3):509-14. doi: 10.1016/0002-9378(93)90609-m. PMID: 8372853
Chesley LC, Sibai BM
Am J Obstet Gynecol 1988 Aug;159(2):275-9. doi: 10.1016/s0002-9378(88)80067-x. PMID: 3044108

Clinical prediction guides

Yi S, Ning L, Xiao H
Ren Fail 2023 Dec;45(1):2238828. doi: 10.1080/0886022X.2023.2238828. PMID: 37482910Free PMC Article
Carnevali L, Cerritelli F, Guolo F, Sgoifo A
J Manipulative Physiol Ther 2021 May;44(4):319-329. Epub 2021 Jan 9 doi: 10.1016/j.jmpt.2020.09.002. PMID: 33436300
Mushlin HM, Lessing N, Wessell AP, Chryssikos T, Pratt N, Caffes N, Oliver J, Aarabi B, Schwartzbauer G
World Neurosurg 2020 Dec;144:e405-e413. Epub 2020 Sep 2 doi: 10.1016/j.wneu.2020.08.163. PMID: 32889182
Ogunleye AA, Sandercock GR, Voss C, Eisenmann JC, Reed K
Public Health Nutr 2013 Nov;16(11):2046-54. Epub 2012 Oct 19 doi: 10.1017/S1368980012004466. PMID: 23083802Free PMC Article
Chesley LC, Sibai BM
Am J Obstet Gynecol 1988 Aug;159(2):275-9. doi: 10.1016/s0002-9378(88)80067-x. PMID: 3044108

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