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Increased risk of pancreatic cancer

MedGen UID:
330845
•Concept ID:
C1842408
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased risk of pancreatic cancer

Professional guidelines

PubMed

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.
Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium
Gut 2020 Jan;69(1):7-17. Epub 2019 Oct 31 doi: 10.1136/gutjnl-2019-319352. PMID: 31672839Free PMC Article
Glucose-lowering treatment of type 2 diabetes. Part II--Glucose-lowering drugs after metformin: a choice based largely on adverse effects.
Prescrire Int 2015 May;24(160):130-5. PMID: 26034806
Hereditary pancreatitis: dilemmas in differential diagnosis and therapeutic approach.
Mastoraki A, Tzortzopoulou A, Tsela S, Danias N, Sakorafas G, Smyrniotis V, Arkadopoulos N
J Gastrointest Cancer 2014 Mar;45(1):22-6. doi: 10.1007/s12029-013-9559-6. PMID: 24242859

Recent clinical studies

Etiology

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
Klein AP
Nat Rev Gastroenterol Hepatol 2021 Jul;18(7):493-502. Epub 2021 May 17 doi: 10.1038/s41575-021-00457-x. PMID: 34002083Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Diagnosis

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
Klein AP
Nat Rev Gastroenterol Hepatol 2021 Jul;18(7):493-502. Epub 2021 May 17 doi: 10.1038/s41575-021-00457-x. PMID: 34002083Free PMC Article
Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.
Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium
Gut 2020 Jan;69(1):7-17. Epub 2019 Oct 31 doi: 10.1136/gutjnl-2019-319352. PMID: 31672839Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426

Therapy

Effects of Berberine against Pancreatitis and Pancreatic Cancer.
Vlavcheski F, O'Neill EJ, Gagacev F, Tsiani E
Molecules 2022 Dec 6;27(23) doi: 10.3390/molecules27238630. PMID: 36500723Free PMC Article
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR Jr
CA Cancer J Clin 2020 Sep;70(5):375-403. Epub 2020 Jul 19 doi: 10.3322/caac.21626. PMID: 32683683Free PMC Article
Chemotherapy and radiotherapy for advanced pancreatic cancer.
Chin V, Nagrial A, Sjoquist K, O'Connor CA, Chantrill L, Biankin AV, Scholten RJ, Yip D
Cochrane Database Syst Rev 2018 Mar 20;3(3):CD011044. doi: 10.1002/14651858.CD011044.pub2. PMID: 29557103Free PMC Article
Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Kirkegård J, Mortensen FV, Cronin-Fenton D
Am J Gastroenterol 2017 Sep;112(9):1366-1372. Epub 2017 Aug 1 doi: 10.1038/ajg.2017.218. PMID: 28762376
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Prognosis

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Global Burden of 5 Major Types of Gastrointestinal Cancer.
Arnold M, Abnet CC, Neale RE, Vignat J, Giovannucci EL, McGlynn KA, Bray F
Gastroenterology 2020 Jul;159(1):335-349.e15. Epub 2020 Apr 2 doi: 10.1053/j.gastro.2020.02.068. PMID: 32247694Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Clinical prediction guides

Humoral Predictors of Malignancy in IPMN: A Review of the Literature.
Nista EC, Schepis T, Candelli M, Giuli L, Pignataro G, Franceschi F, Gasbarrini A, Ojetti V
Int J Mol Sci 2021 Nov 27;22(23) doi: 10.3390/ijms222312839. PMID: 34884643Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Worldwide Burden of, Risk Factors for, and Trends in Pancreatic Cancer.
Huang J, Lok V, Ngai CH, Zhang L, Yuan J, Lao XQ, Ng K, Chong C, Zheng ZJ, Wong MCS
Gastroenterology 2021 Feb;160(3):744-754. Epub 2020 Oct 13 doi: 10.1053/j.gastro.2020.10.007. PMID: 33058868
Pancreatic neuroendocrine tumors.
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Kirkegård J, Mortensen FV, Cronin-Fenton D
Am J Gastroenterol 2017 Sep;112(9):1366-1372. Epub 2017 Aug 1 doi: 10.1038/ajg.2017.218. PMID: 28762376

Recent systematic reviews

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.
Kristensen SL, Rørth R, Jhund PS, Docherty KF, Sattar N, Preiss D, Køber L, Petrie MC, McMurray JJV
Lancet Diabetes Endocrinol 2019 Oct;7(10):776-785. Epub 2019 Aug 14 doi: 10.1016/S2213-8587(19)30249-9. PMID: 31422062
Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Kirkegård J, Mortensen FV, Cronin-Fenton D
Am J Gastroenterol 2017 Sep;112(9):1366-1372. Epub 2017 Aug 1 doi: 10.1038/ajg.2017.218. PMID: 28762376
Alcohol consumption and risk of cancer: a systematic literature review.
de Menezes RF, Bergmann A, Thuler LC
Asian Pac J Cancer Prev 2013;14(9):4965-72. doi: 10.7314/apjcp.2013.14.9.4965. PMID: 24175760
Metabolic syndrome and risk of cancer: a systematic review and meta-analysis.
Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D
Diabetes Care 2012 Nov;35(11):2402-11. doi: 10.2337/dc12-0336. PMID: 23093685Free PMC Article
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M
Lancet 2008 Feb 16;371(9612):569-78. doi: 10.1016/S0140-6736(08)60269-X. PMID: 18280327

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    Practice guidelines

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