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Neurofibromatosis-pheochromocytoma-duodenal carcinoid syndrome

MedGen UID:
331696
•Concept ID:
C1834232
•
Disease or Syndrome
Synonym: Duodenal carcinoid syndrome
 
Monarch Initiative: MONDO:0008079
OMIM®: 162240

Professional guidelines

PubMed

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH; ESC Scientific Document Group
Eur Heart J 2022 Nov 1;43(41):4229-4361. doi: 10.1093/eurheartj/ehac244. PMID: 36017568
Carcinoid Heart Disease: Pathophysiology, Pathology, Clinical Manifestations, and Management.
Jin C, Sharma AN, Thevakumar B, Majid M, Al Chalaby S, Takahashi N, Tanious A, Arockiam AD, Beri N, Amsterdam EA
Cardiology 2021;146(1):65-73. Epub 2020 Oct 16 doi: 10.1159/000507847. PMID: 33070143
Treatment of symptomatic neuroendocrine tumor syndromes: recent advances and controversies.
Ito T, Lee L, Jensen RT
Expert Opin Pharmacother 2016 Nov;17(16):2191-2205. Epub 2016 Sep 23 doi: 10.1080/14656566.2016.1236916. PMID: 27635672Free PMC Article

Recent clinical studies

Etiology

Carcinoid tumors outside the abdomen.
Koehler K, Iams WT
Cancer Med 2023 Apr;12(7):7893-7903. Epub 2022 Dec 22 doi: 10.1002/cam4.5564. PMID: 36560885Free PMC Article
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH; ESC Scientific Document Group
Eur Heart J Cardiovasc Imaging 2022 Sep 10;23(10):e333-e465. doi: 10.1093/ehjci/jeac106. PMID: 36017575
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH; ESC Scientific Document Group
Eur Heart J 2022 Nov 1;43(41):4229-4361. doi: 10.1093/eurheartj/ehac244. PMID: 36017568
Shifting Paradigms in the Pathophysiology and Treatment of Carcinoid Crisis.
Maxwell JE, Naraev B, Halperin DM, Choti MA, Halfdanarson TR
Ann Surg Oncol 2022 May;29(5):3072-3084. Epub 2022 Feb 14 doi: 10.1245/s10434-022-11371-0. PMID: 35165817
Anaphylaxis.
LoVerde D, Iweala OI, Eginli A, Krishnaswamy G
Chest 2018 Feb;153(2):528-543. Epub 2017 Aug 8 doi: 10.1016/j.chest.2017.07.033. PMID: 28800865Free PMC Article

Diagnosis

European Neuroendocrine Tumor Society (ENETS) 2022 Guidance Paper for Carcinoid Syndrome and Carcinoid Heart Disease.
Grozinsky-Glasberg S, Davar J, Hofland J, Dobson R, Prasad V, Pascher A, Denecke T, Tesselaar MET, Panzuto F, Albåge A, Connolly HM, Obadia JF, Riechelmann R, Toumpanakis C
J Neuroendocrinol 2022 Jul;34(7):e13146. Epub 2022 May 25 doi: 10.1111/jne.13146. PMID: 35613326Free PMC Article
Anesthesia for Endocrine Emergencies.
Peramunage D, Nikravan S
Anesthesiol Clin 2020 Mar;38(1):149-163. Epub 2020 Jan 2 doi: 10.1016/j.anclin.2019.10.006. PMID: 32008649
Carcinoid-syndrome: recent advances, current status and controversies.
Ito T, Lee L, Jensen RT
Curr Opin Endocrinol Diabetes Obes 2018 Feb;25(1):22-35. doi: 10.1097/MED.0000000000000376. PMID: 29120923Free PMC Article
Carcinoid heart disease.
Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Heart 2017 Oct;103(19):1488-1495. Epub 2017 Jun 8 doi: 10.1136/heartjnl-2017-311261. PMID: 28596302
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366

Therapy

Shifting Paradigms in the Pathophysiology and Treatment of Carcinoid Crisis.
Maxwell JE, Naraev B, Halperin DM, Choti MA, Halfdanarson TR
Ann Surg Oncol 2022 May;29(5):3072-3084. Epub 2022 Feb 14 doi: 10.1245/s10434-022-11371-0. PMID: 35165817
Gastroenteropancreatic Neuroendocrine Tumors.
Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
Carcinoid-syndrome: recent advances, current status and controversies.
Ito T, Lee L, Jensen RT
Curr Opin Endocrinol Diabetes Obes 2018 Feb;25(1):22-35. doi: 10.1097/MED.0000000000000376. PMID: 29120923Free PMC Article
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Carcinoid syndrome.
Bendelow J, Apps E, Jones LE, Poston GJ
Eur J Surg Oncol 2008 Mar;34(3):289-96. Epub 2007 Dec 18 doi: 10.1016/j.ejso.2007.07.202. PMID: 18068329

Prognosis

Carcinoid-syndrome: recent advances, current status and controversies.
Ito T, Lee L, Jensen RT
Curr Opin Endocrinol Diabetes Obes 2018 Feb;25(1):22-35. doi: 10.1097/MED.0000000000000376. PMID: 29120923Free PMC Article
Carcinoid heart disease.
Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Heart 2017 Oct;103(19):1488-1495. Epub 2017 Jun 8 doi: 10.1136/heartjnl-2017-311261. PMID: 28596302
Neuroendocrine Tumors.
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Carcinoid syndrome.
Bendelow J, Apps E, Jones LE, Poston GJ
Eur J Surg Oncol 2008 Mar;34(3):289-96. Epub 2007 Dec 18 doi: 10.1016/j.ejso.2007.07.202. PMID: 18068329

Clinical prediction guides

Expressions of Cushing's syndrome in multiple endocrine neoplasia type 1.
Simonds WF
Front Endocrinol (Lausanne) 2023;14:1183297. Epub 2023 Jun 20 doi: 10.3389/fendo.2023.1183297. PMID: 37409236Free PMC Article
Cardiac Imaging in Carcinoid Heart Disease.
Baron T, Bergsten J, Albåge A, Lundin L, Sörensen J, Öberg K, Flachskampf FA
JACC Cardiovasc Imaging 2021 Nov;14(11):2240-2253. Epub 2021 Apr 14 doi: 10.1016/j.jcmg.2020.12.030. PMID: 33865761
Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger-Ellison Syndrome.
Lee L, Ramos-Alvarez I, Ito T, Jensen RT
Int J Mol Sci 2019 Oct 16;20(20) doi: 10.3390/ijms20205128. PMID: 31623145Free PMC Article
Gastroenteropancreatic Neuroendocrine Tumors.
Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
Carcinoid heart disease.
Bernheim AM, Connolly HM, Hobday TJ, Abel MD, Pellikka PA
Prog Cardiovasc Dis 2007 May-Jun;49(6):439-51. doi: 10.1016/j.pcad.2006.12.002. PMID: 17498524

Recent systematic reviews

A Systematic Review of Economic and Quality-of-Life Research in Carcinoid Syndrome.
Pan IW, Halperin DM, Kim B, Yao JC, Shih YT
Pharmacoeconomics 2021 Nov;39(11):1271-1297. Epub 2021 Aug 11 doi: 10.1007/s40273-021-01071-0. PMID: 34378163Free PMC Article
Systemic Treatment Options for Carcinoid Syndrome: A Systematic Review.
Wolin EM, Benson Iii AB
Oncology 2019;96(6):273-289. Epub 2019 Apr 24 doi: 10.1159/000499049. PMID: 31018209
Management of carcinoid syndrome: a systematic review and meta-analysis.
Hofland J, Herrera-Martínez AD, Zandee WT, de Herder WW
Endocr Relat Cancer 2019 Mar;26(3):R145-R156. doi: 10.1530/ERC-18-0495. PMID: 30608900
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Ectopic ACTH syndrome.
Isidori AM, Lenzi A
Arq Bras Endocrinol Metabol 2007 Nov;51(8):1217-25. doi: 10.1590/s0004-27302007000800007. PMID: 18209859

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