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Abnormal oral glucose tolerance

MedGen UID:
339758
Concept ID:
C1847425
Finding
Synonym: Abnormal glucose oral tolerance test
 
HPO: HP:0004924

Definition

An abnormal resistance to glucose, i.e., a reduction in the ability to maintain glucose levels in the blood stream within normal limits following oral administration of glucose. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal oral glucose tolerance

Conditions with this feature

Congenital glucose-galactose malabsorption
MedGen UID:
78647
Concept ID:
C0268186
Disease or Syndrome
Glucose/galactose malabsorption (GGM) is a rare autosomal recessive disorder caused by a defect in glucose and galactose transport across the intestinal brush border. Patients with GGM present with neonatal onset of severe life-threatening watery diarrhea and dehydration. If diagnosed and treated properly, patients can fully recover and show normal growth and development (summary by Xin and Wang, 2011).
Optic atrophy--spastic paraplegia syndrome
MedGen UID:
326914
Concept ID:
C1839565
Disease or Syndrome

Professional guidelines

PubMed

Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article
Geifman-Holtzman O, Machtinger R, Spiliopoulos M, Schiff E, Koren-Morag N, Dulitzki M
Arch Gynecol Obstet 2010 May;281(5):817-21. Epub 2009 Jul 11 doi: 10.1007/s00404-009-1160-7. PMID: 19593579
Harris MI
Prim Care 1988 Jun;15(2):205-25. PMID: 3290916

Recent clinical studies

Etiology

Kotzaeridi G, Blätter J, Eppel D, Rosicky I, Linder T, Geissler F, Huhn EA, Hösli I, Tura A, Göbl CS
Eur J Clin Invest 2021 Sep;51(9):e13628. Epub 2021 Jun 13 doi: 10.1111/eci.13628. PMID: 34120352Free PMC Article
Mohr Sasson A, Shats M, Goichberg Z, Mazaki-Tovi S, Morag I, Hendler I
J Matern Fetal Neonatal Med 2021 Dec;34(23):3928-3932. Epub 2019 Dec 18 doi: 10.1080/14767058.2019.1702945. PMID: 31851555
Arbib N, Gabbay-Benziv R, Aviram A, Sneh-Arbib O, Wiznitzer A, Hod M, Chen R, Hadar E
J Matern Fetal Neonatal Med 2017 Apr;30(8):917-921. Epub 2016 Jun 8 doi: 10.1080/14767058.2016.1190825. PMID: 27186963
Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article
Harris MI
Prim Care 1988 Jun;15(2):205-25. PMID: 3290916

Diagnosis

Kotzaeridi G, Blätter J, Eppel D, Rosicky I, Linder T, Geissler F, Huhn EA, Hösli I, Tura A, Göbl CS
Eur J Clin Invest 2021 Sep;51(9):e13628. Epub 2021 Jun 13 doi: 10.1111/eci.13628. PMID: 34120352Free PMC Article
Mohr Sasson A, Shats M, Goichberg Z, Mazaki-Tovi S, Morag I, Hendler I
J Matern Fetal Neonatal Med 2021 Dec;34(23):3928-3932. Epub 2019 Dec 18 doi: 10.1080/14767058.2019.1702945. PMID: 31851555
Ketumarn N, Boriboonhirunsarn D
J Matern Fetal Neonatal Med 2018 Aug;31(16):2109-2114. Epub 2017 Jun 9 doi: 10.1080/14767058.2017.1336224. PMID: 28553734
Arbib N, Gabbay-Benziv R, Aviram A, Sneh-Arbib O, Wiznitzer A, Hod M, Chen R, Hadar E
J Matern Fetal Neonatal Med 2017 Apr;30(8):917-921. Epub 2016 Jun 8 doi: 10.1080/14767058.2016.1190825. PMID: 27186963
Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article

Therapy

Kotzaeridi G, Blätter J, Eppel D, Rosicky I, Linder T, Geissler F, Huhn EA, Hösli I, Tura A, Göbl CS
Eur J Clin Invest 2021 Sep;51(9):e13628. Epub 2021 Jun 13 doi: 10.1111/eci.13628. PMID: 34120352Free PMC Article
Aumar M, Gottrand F, Chalouhi C, Blanc S, Thomassin N, Piloquet H, Gastineau S, Schneider A, Krishnan U, Duvoisin G, Turck D, Coopman S, Michaud L
J Pediatr Gastroenterol Nutr 2020 Jun;70(6):820-824. doi: 10.1097/MPG.0000000000002651. PMID: 32443041
Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article
Main DM, Main EK, Strong SE, Gabbe SG
Am J Obstet Gynecol 1985 Aug 15;152(8):1031-3. doi: 10.1016/0002-9378(85)90553-8. PMID: 4025449
Troxler RG, Trabal JF, Lancaster MC
Aviat Space Environ Med 1975 May;46(5):729-35. PMID: 1131139

Prognosis

Aumar M, Gottrand F, Chalouhi C, Blanc S, Thomassin N, Piloquet H, Gastineau S, Schneider A, Krishnan U, Duvoisin G, Turck D, Coopman S, Michaud L
J Pediatr Gastroenterol Nutr 2020 Jun;70(6):820-824. doi: 10.1097/MPG.0000000000002651. PMID: 32443041
Sanda S; Type 1 Diabetes TrialNet Study Group
Pediatr Diabetes 2018 Mar;19(2):271-276. Epub 2017 Jul 14 doi: 10.1111/pedi.12542. PMID: 28707353Free PMC Article
Ketumarn N, Boriboonhirunsarn D
J Matern Fetal Neonatal Med 2018 Aug;31(16):2109-2114. Epub 2017 Jun 9 doi: 10.1080/14767058.2017.1336224. PMID: 28553734
Ellerbrock J, Bohnen JMHA, Lopes van Balen VA, Mulder EG, Aardenburg R, Spaanderman MEA
Gynecol Endocrinol 2017 Dec;33(12):911-917. Epub 2017 Aug 28 doi: 10.1080/09513590.2017.1369516. PMID: 28846055
Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article

Clinical prediction guides

Kotzaeridi G, Blätter J, Eppel D, Rosicky I, Linder T, Geissler F, Huhn EA, Hösli I, Tura A, Göbl CS
Eur J Clin Invest 2021 Sep;51(9):e13628. Epub 2021 Jun 13 doi: 10.1111/eci.13628. PMID: 34120352Free PMC Article
Mohr Sasson A, Shats M, Goichberg Z, Mazaki-Tovi S, Morag I, Hendler I
J Matern Fetal Neonatal Med 2021 Dec;34(23):3928-3932. Epub 2019 Dec 18 doi: 10.1080/14767058.2019.1702945. PMID: 31851555
Aumar M, Gottrand F, Chalouhi C, Blanc S, Thomassin N, Piloquet H, Gastineau S, Schneider A, Krishnan U, Duvoisin G, Turck D, Coopman S, Michaud L
J Pediatr Gastroenterol Nutr 2020 Jun;70(6):820-824. doi: 10.1097/MPG.0000000000002651. PMID: 32443041
Ellerbrock J, Bohnen JMHA, Lopes van Balen VA, Mulder EG, Aardenburg R, Spaanderman MEA
Gynecol Endocrinol 2017 Dec;33(12):911-917. Epub 2017 Aug 28 doi: 10.1080/09513590.2017.1369516. PMID: 28846055
Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Aktary WM, Pasichnyk D, Seida JC, Donovan L
Evid Rep Technol Assess (Full Rep) 2012 Oct;(210):1-327. PMID: 24423035Free PMC Article

Recent systematic reviews

Ellerbrock J, Bohnen JMHA, Lopes van Balen VA, Mulder EG, Aardenburg R, Spaanderman MEA
Gynecol Endocrinol 2017 Dec;33(12):911-917. Epub 2017 Aug 28 doi: 10.1080/09513590.2017.1369516. PMID: 28846055

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