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Retinoschisis of fovea

MedGen UID:
340313
•Concept ID:
C1849397
•
Disease or Syndrome
Synonyms: Familial foveal retinoschisis; Foveal retinoschisis
 
Monarch Initiative: MONDO:0009988
OMIM®: 268080

Recent clinical studies

Etiology

Myopic Foveoschisis Completely Resolves within 12 Months after Vitrectomy.
Beaumont W, Couturier A, Gaudric A, Tadayoni R, Philippakis E
Ophthalmol Retina 2022 Dec;6(12):1221-1230. Epub 2022 Jun 14 doi: 10.1016/j.oret.2022.06.003. PMID: 35709959
The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission.
Govetto A, Hubschman JP, Sarraf D, Figueroa MS, Bottoni F, dell'Omo R, Curcio CA, Seidenari P, Delledonne G, Gunzenhauser R, Ferrara M, Au A, Virgili G, Scialdone A, Repetto R, Romano MR
Br J Ophthalmol 2020 Apr;104(4):466-472. Epub 2019 Jul 20 doi: 10.1136/bjophthalmol-2019-314245. PMID: 31326893
Long-term follow-up of a CRB1-associated maculopathy.
Mucciolo DP, Murro V, Giorgio D, Passerini I, Sodi A, Virgili G, Rizzo S
Ophthalmic Genet 2018 Aug;39(4):522-525. Epub 2018 Jun 5 doi: 10.1080/13816810.2018.1479431. PMID: 29869924
Anatomical and visual outcomes in high myopic macular hole (HM-MH) without retinal detachment: a review.
Alkabes M, Pichi F, Nucci P, Massaro D, Dutra Medeiros M, Corcostegui B, Mateo C
Graefes Arch Clin Exp Ophthalmol 2014 Feb;252(2):191-9. Epub 2014 Jan 3 doi: 10.1007/s00417-013-2555-5. PMID: 24384802
Natural course and surgical management of high myopic foveoschisis.
Rey A, Jürgens I, Maseras X, Carbajal M
Ophthalmologica 2014;231(1):45-50. Epub 2013 Nov 12 doi: 10.1159/000355324. PMID: 24246446

Diagnosis

Myopic Foveoschisis Completely Resolves within 12 Months after Vitrectomy.
Beaumont W, Couturier A, Gaudric A, Tadayoni R, Philippakis E
Ophthalmol Retina 2022 Dec;6(12):1221-1230. Epub 2022 Jun 14 doi: 10.1016/j.oret.2022.06.003. PMID: 35709959
Identification of a novel CRB1 variant in a compound heterozygous state in a patient with CRB1-associated maculopathy and foveal retinoschisis.
Cheng Z, Hagan R, Yeo DCM
Ophthalmic Genet 2022 Apr;43(2):253-257. Epub 2021 Nov 16 doi: 10.1080/13816810.2021.1998551. PMID: 34783605
Long-term follow-up of a CRB1-associated maculopathy.
Mucciolo DP, Murro V, Giorgio D, Passerini I, Sodi A, Virgili G, Rizzo S
Ophthalmic Genet 2018 Aug;39(4):522-525. Epub 2018 Jun 5 doi: 10.1080/13816810.2018.1479431. PMID: 29869924
SURGICAL TREATMENT OF A MACULAR HOLE IN X-LINKED RETINOSCHISIS.
Stein GE, Lee SE, Chen RWS, Yannuzzi L, Chang S
Retin Cases Brief Rep 2017 Summer;11(3):246-248. doi: 10.1097/ICB.0000000000000332. PMID: 27203560
Natural course and surgical management of high myopic foveoschisis.
Rey A, Jürgens I, Maseras X, Carbajal M
Ophthalmologica 2014;231(1):45-50. Epub 2013 Nov 12 doi: 10.1159/000355324. PMID: 24246446

Therapy

LONG-TERM OUTCOMES OF 23-GAUGE PARS PLANA VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING AND GAS TAMPONADE FOR MYOPIC TRACTION MACULOPATHY: A Prospective Study.
Figueroa MS, Ruiz-Moreno JM, Gonzalez del Valle F, Govetto A, de la Vega C, Plascencia RN, Contreras I, Medina JL
Retina 2015 Sep;35(9):1836-43. doi: 10.1097/IAE.0000000000000554. PMID: 25946689
Topical brinzolamide for foveal schisis in juvenile retinoschisis.
Yang FP, Willyasti K, Leo SW
J AAPOS 2013 Apr;17(2):225-7. Epub 2013 Mar 29 doi: 10.1016/j.jaapos.2012.11.016. PMID: 23541677
Foveola nonpeeling technique in internal limiting membrane peeling of myopic foveoschisis surgery.
Ho TC, Chen MS, Huang JS, Shih YF, Ho H, Huang YH
Retina 2012 Mar;32(3):631-4. doi: 10.1097/IAE.0B013E31824D0A4B. PMID: 22374159
Macular buckling for eyes with myopic foveoschisis secondary to posterior staphyloma.
Mateo C, Burés-Jelstrup A, Navarro R, Corcóstegui B
Retina 2012 Jun;32(6):1121-8. doi: 10.1097/IAE.0b013e31822e5c32. PMID: 22027863
Vitrectomy and internal limiting membrane peeling with and without gas tamponade for myopic foveoschisis.
Kim KS, Lee SB, Lee WK
Am J Ophthalmol 2012 Feb;153(2):320-326.e1. Epub 2011 Oct 8 doi: 10.1016/j.ajo.2011.07.007. PMID: 21982957

Prognosis

Identification of a novel CRB1 variant in a compound heterozygous state in a patient with CRB1-associated maculopathy and foveal retinoschisis.
Cheng Z, Hagan R, Yeo DCM
Ophthalmic Genet 2022 Apr;43(2):253-257. Epub 2021 Nov 16 doi: 10.1080/13816810.2021.1998551. PMID: 34783605
The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission.
Govetto A, Hubschman JP, Sarraf D, Figueroa MS, Bottoni F, dell'Omo R, Curcio CA, Seidenari P, Delledonne G, Gunzenhauser R, Ferrara M, Au A, Virgili G, Scialdone A, Repetto R, Romano MR
Br J Ophthalmol 2020 Apr;104(4):466-472. Epub 2019 Jul 20 doi: 10.1136/bjophthalmol-2019-314245. PMID: 31326893
Long-term follow-up of a CRB1-associated maculopathy.
Mucciolo DP, Murro V, Giorgio D, Passerini I, Sodi A, Virgili G, Rizzo S
Ophthalmic Genet 2018 Aug;39(4):522-525. Epub 2018 Jun 5 doi: 10.1080/13816810.2018.1479431. PMID: 29869924
Anatomical and visual outcomes in high myopic macular hole (HM-MH) without retinal detachment: a review.
Alkabes M, Pichi F, Nucci P, Massaro D, Dutra Medeiros M, Corcostegui B, Mateo C
Graefes Arch Clin Exp Ophthalmol 2014 Feb;252(2):191-9. Epub 2014 Jan 3 doi: 10.1007/s00417-013-2555-5. PMID: 24384802
Natural course and surgical management of high myopic foveoschisis.
Rey A, Jürgens I, Maseras X, Carbajal M
Ophthalmologica 2014;231(1):45-50. Epub 2013 Nov 12 doi: 10.1159/000355324. PMID: 24246446

Clinical prediction guides

Myopic Foveoschisis Completely Resolves within 12 Months after Vitrectomy.
Beaumont W, Couturier A, Gaudric A, Tadayoni R, Philippakis E
Ophthalmol Retina 2022 Dec;6(12):1221-1230. Epub 2022 Jun 14 doi: 10.1016/j.oret.2022.06.003. PMID: 35709959
Identification of a novel CRB1 variant in a compound heterozygous state in a patient with CRB1-associated maculopathy and foveal retinoschisis.
Cheng Z, Hagan R, Yeo DCM
Ophthalmic Genet 2022 Apr;43(2):253-257. Epub 2021 Nov 16 doi: 10.1080/13816810.2021.1998551. PMID: 34783605
The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission.
Govetto A, Hubschman JP, Sarraf D, Figueroa MS, Bottoni F, dell'Omo R, Curcio CA, Seidenari P, Delledonne G, Gunzenhauser R, Ferrara M, Au A, Virgili G, Scialdone A, Repetto R, Romano MR
Br J Ophthalmol 2020 Apr;104(4):466-472. Epub 2019 Jul 20 doi: 10.1136/bjophthalmol-2019-314245. PMID: 31326893
Long-term follow-up of a CRB1-associated maculopathy.
Mucciolo DP, Murro V, Giorgio D, Passerini I, Sodi A, Virgili G, Rizzo S
Ophthalmic Genet 2018 Aug;39(4):522-525. Epub 2018 Jun 5 doi: 10.1080/13816810.2018.1479431. PMID: 29869924
Anatomical and visual outcomes in high myopic macular hole (HM-MH) without retinal detachment: a review.
Alkabes M, Pichi F, Nucci P, Massaro D, Dutra Medeiros M, Corcostegui B, Mateo C
Graefes Arch Clin Exp Ophthalmol 2014 Feb;252(2):191-9. Epub 2014 Jan 3 doi: 10.1007/s00417-013-2555-5. PMID: 24384802

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