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Spinal muscular atrophy with microcephaly and mental subnormality

MedGen UID:
341384
Concept ID:
C1849108
Disease or Syndrome
Synonym: Spinal Muscular Atrophy with Microcephaly and Mental Subnormality
 
Monarch Initiative: MONDO:0010055
OMIM®: 271110

Clinical features

From HPO
Intellectual disability
MedGen UID:
811461
Concept ID:
C3714756
Mental or Behavioral Dysfunction
Intellectual disability, previously referred to as mental retardation, is characterized by subnormal intellectual functioning that occurs during the developmental period. It is defined by an IQ score below 70.
Proximal spinal muscular atrophy
MedGen UID:
870510
Concept ID:
C4024957
Disease or Syndrome
Proximal spinal muscular atrophy, i.e., muscular weakness and atrophy related to loss of the motor neurons of the spinal cord and brainstem.
Microcephaly
MedGen UID:
1644158
Concept ID:
C4551563
Finding
Head circumference below 2 standard deviations below the mean for age and gender.

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