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Migraine with or without aura, susceptibility to, 10

MedGen UID:
341839
•Concept ID:
C1857752
•
Finding
Synonyms: Migraine with or without aura 10; MIGRAINE WITH PULSATION
 
Monarch Initiative: MONDO:0012440
OMIM®: 610208

Clinical features

From HPO
Nausea
MedGen UID:
10196
•Concept ID:
C0027497
•
Sign or Symptom
A sensation of unease in the stomach together with an urge to vomit.
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Vomiting
MedGen UID:
12124
•Concept ID:
C0042963
•
Sign or Symptom
Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions.
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Photophobia
MedGen UID:
43220
•Concept ID:
C0085636
•
Sign or Symptom
Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
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Migraine with aura
MedGen UID:
57822
•Concept ID:
C0154723
•
Disease or Syndrome
A type of migraine in which there is an aura characterized by focal neurological phenomena that usually proceed, but may accompany or occur in the absence of, the headache. The symptoms of an aura may include fully reversible visual, sensory, and speech symptoms but not motor weakness. Visual symptoms may include flickering lights, spots and lines and/or loss of vision and/or unilateral sensory symptoms such as paresthesias or numbness. At least one of the symptoms of an aura develops gradually over 5 or more minutes and/or different symptoms occur in succession.
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Migraine without aura
MedGen UID:
137899
•Concept ID:
C0338480
•
Disease or Syndrome
Repeated headache attacks lasting 4-72 h fulfilling at least two of the following criteria
See: Feature record | Search on this feature
Phonophobia
MedGen UID:
155864
•Concept ID:
C0751466
•
Mental or Behavioral Dysfunction
An abnormally heightened sensitivity to loud sounds.
See: Feature record | Search on this feature
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Professional guidelines

PubMed

Management of chronic migraine.
Hovaguimian A, Roth J
BMJ 2022 Oct 10;379:e067670. doi: 10.1136/bmj-2021-067670. PMID: 36216384
The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice.
Ailani J, Burch RC, Robbins MS; Board of Directors of the American Headache Society
Headache 2021 Jul;61(7):1021-1039. Epub 2021 Jun 23 doi: 10.1111/head.14153. PMID: 34160823
Migraine and Tension-Type Headache: Diagnosis and Treatment.
Burch R
Med Clin North Am 2019 Mar;103(2):215-233. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.003. PMID: 30704678

Recent clinical studies

Etiology

Genetics of migraine: where are we now?
Grangeon L, Lange KS, Waliszewska-Prosół M, Onan D, Marschollek K, Wiels W, Mikulenka P, Farham F, Gollion C, Ducros A; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2023 Feb 20;24(1):12. doi: 10.1186/s10194-023-01547-8. PMID: 36800925Free PMC Article
Monoclonal Antibodies against Calcitonin Gene-Related Peptide for Migraine Prophylaxis: A Systematic Review of Real-World Data.
Pavelic AR, Wöber C, Riederer F, Zebenholzer K
Cells 2022 Dec 29;12(1) doi: 10.3390/cells12010143. PMID: 36611935Free PMC Article
Complementary and Integrative Medicine for Episodic Migraine: an Update of Evidence from the Last 3 Years.
Wells RE, Beuthin J, Granetzke L
Curr Pain Headache Rep 2019 Feb 21;23(2):10. doi: 10.1007/s11916-019-0750-8. PMID: 30790138Free PMC Article
Triptans in the Acute Treatment of Migraine: A Systematic Review and Network Meta-Analysis.
Cameron C, Kelly S, Hsieh SC, Murphy M, Chen L, Kotb A, Peterson J, Coyle D, Skidmore B, Gomes T, Clifford T, Wells G
Headache 2015 Jul-Aug;55 Suppl 4:221-35. Epub 2015 Jul 14 doi: 10.1111/head.12601. PMID: 26178694
Chronic migraine.
Schwedt TJ
BMJ 2014 Mar 24;348:g1416. doi: 10.1136/bmj.g1416. PMID: 24662044

Diagnosis

Pathophysiology and Therapy of Associated Features of Migraine.
Villar-Martinez MD, Goadsby PJ
Cells 2022 Sep 5;11(17) doi: 10.3390/cells11172767. PMID: 36078174Free PMC Article
Migraine review for general practice.
Aguilar-Shea AL, Membrilla Md JA, Diaz-de-Teran J
Aten Primaria 2022 Feb;54(2):102208. Epub 2021 Nov 16 doi: 10.1016/j.aprim.2021.102208. PMID: 34798397Free PMC Article
Acute Migraine Headache: Treatment Strategies.
Mayans L, Walling A
Am Fam Physician 2018 Feb 15;97(4):243-251. PMID: 29671521
Migraine.
Dodick DW
Lancet 2018 Mar 31;391(10127):1315-1330. Epub 2018 Mar 6 doi: 10.1016/S0140-6736(18)30478-1. PMID: 29523342
Migraine.
Silberstein SD
Lancet 2004 Jan 31;363(9406):381-91. doi: 10.1016/S0140-6736(04)15440-8. PMID: 15070571

Therapy

Evaluating the efficacy of CGRP mAbs and gepants for the preventive treatment of migraine: A systematic review and network meta-analysis of phase 3 randomised controlled trials.
Haghdoost F, Puledda F, Garcia-Azorin D, Huessler EM, Messina R, Pozo-Rosich P
Cephalalgia 2023 Apr;43(4):3331024231159366. doi: 10.1177/03331024231159366. PMID: 36855951
Ginger for Migraine.
Andrade C
J Clin Psychiatry 2021 Nov 30;82(6) doi: 10.4088/JCP.21f14325. PMID: 34851560
Cognitive dysfunction and migraine.
Vuralli D, Ayata C, Bolay H
J Headache Pain 2018 Nov 15;19(1):109. doi: 10.1186/s10194-018-0933-4. PMID: 30442090Free PMC Article
Non-Pharmacological Approaches for Migraine.
Puledda F, Shields K
Neurotherapeutics 2018 Apr;15(2):336-345. doi: 10.1007/s13311-018-0623-6. PMID: 29616493Free PMC Article
Menstrual Migraine and Treatment Options: Review.
Maasumi K, Tepper SJ, Kriegler JS
Headache 2017 Feb;57(2):194-208. Epub 2016 Dec 2 doi: 10.1111/head.12978. PMID: 27910087

Prognosis

Migrainous infarction.
Chiang CC, Chen SP
Handb Clin Neurol 2024;199:465-474. doi: 10.1016/B978-0-12-823357-3.00021-5. PMID: 38307663
Global, regional, and national burden of migraine in 204 countries and territories, 1990 to 2019.
Safiri S, Pourfathi H, Eagan A, Mansournia MA, Khodayari MT, Sullman MJM, Kaufman J, Collins G, Dai H, Bragazzi NL, Kolahi AA
Pain 2022 Feb 1;163(2):e293-e309. doi: 10.1097/j.pain.0000000000002275. PMID: 34001771
Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP.
Krause DN, Warfvinge K, Haanes KA, Edvinsson L
Nat Rev Neurol 2021 Oct;17(10):621-633. Epub 2021 Sep 20 doi: 10.1038/s41582-021-00544-2. PMID: 34545218
Review of migraine incidence and management in obstetrics and gynaecology.
Tanos V, Raad EA, Berry KE, Toney ZA
Eur J Obstet Gynecol Reprod Biol 2019 Sep;240:248-255. Epub 2019 Jul 17 doi: 10.1016/j.ejogrb.2019.07.021. PMID: 31336231
Migraine-associated vestibulopathy.
Honaker J, Samy RN
Curr Opin Otolaryngol Head Neck Surg 2008 Oct;16(5):412-5. doi: 10.1097/MOO.0b013e32830a4a02. PMID: 18797281

Clinical prediction guides

Migraine and the Gender Divide.
Vanood A, Rangel IC, Starling AJ
Neurol Clin 2023 May;41(2):231-247. doi: 10.1016/j.ncl.2023.01.002. PMID: 37030955
Cognitive Behavioral Therapy for Migraine Headache: A Systematic Review and Meta-Analysis.
Bae JY, Sung HK, Kwon NY, Go HY, Kim TJ, Shin SM, Lee S
Medicina (Kaunas) 2021 Dec 28;58(1) doi: 10.3390/medicina58010044. PMID: 35056352Free PMC Article
Triggers, Protectors, and Predictors in Episodic Migraine.
Marmura MJ
Curr Pain Headache Rep 2018 Oct 5;22(12):81. doi: 10.1007/s11916-018-0734-0. PMID: 30291562
Acute stroke differential diagnosis: Stroke mimics.
Vilela P
Eur J Radiol 2017 Nov;96:133-144. Epub 2017 May 5 doi: 10.1016/j.ejrad.2017.05.008. PMID: 28551302
Vestibular migraine.
von Brevern M, Lempert T
Handb Clin Neurol 2016;137:301-16. doi: 10.1016/B978-0-444-63437-5.00022-4. PMID: 27638080

Recent systematic reviews

European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention - 2022 update.
Sacco S, Amin FM, Ashina M, Bendtsen L, Deligianni CI, Gil-Gouveia R, Katsarava Z, MaassenVanDenBrink A, Martelletti P, Mitsikostas DD, Ornello R, Reuter U, Sanchez-Del-Rio M, Sinclair AJ, Terwindt G, Uluduz D, Versijpt J, Lampl C
J Headache Pain 2022 Jun 11;23(1):67. doi: 10.1186/s10194-022-01431-x. PMID: 35690723Free PMC Article
Botox (OnabotulinumtoxinA) for Treatment of Migraine Symptoms: A Systematic Review.
Shaterian N, Shaterian N, Ghanaatpisheh A, Abbasi F, Daniali S, Jahromi MJ, Sanie MS, Abdoli A
Pain Res Manag 2022;2022:3284446. Epub 2022 Mar 31 doi: 10.1155/2022/3284446. PMID: 35401888Free PMC Article
Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis.
VanderPluym JH, Halker Singh RB, Urtecho M, Morrow AS, Nayfeh T, Torres Roldan VD, Farah MH, Hasan B, Saadi S, Shah S, Abd-Rabu R, Daraz L, Prokop LJ, Murad MH, Wang Z
JAMA 2021 Jun 15;325(23):2357-2369. doi: 10.1001/jama.2021.7939. PMID: 34128998Free PMC Article
Migraine and sleep disorders: a systematic review.
Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T, Hubalek IA, Marchenko Y, Overeem LH, Piroso S, Tkachev A, Martelletti P, Sacco S; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2020 Oct 27;21(1):126. doi: 10.1186/s10194-020-01192-5. PMID: 33109076Free PMC Article
Manual therapies for migraine: a systematic review.
Chaibi A, Tuchin PJ, Russell MB
J Headache Pain 2011 Apr;12(2):127-33. Epub 2011 Feb 5 doi: 10.1007/s10194-011-0296-6. PMID: 21298314Free PMC Article

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