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Mild hyperkeratosis

MedGen UID:
343664
•Concept ID:
C1851844
•
Finding
Synonym: Hyperkeratosis, mild

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMild hyperkeratosis

Professional guidelines

PubMed

Management of Laryngeal Dysplasia and Early Invasive Cancer.
Hrelec C
Curr Treat Options Oncol 2021 Aug 23;22(10):90. doi: 10.1007/s11864-021-00881-w. PMID: 34424405

Recent clinical studies

Etiology

Multinucleated atypia of the vulva.
Rausch D, Angermeier M, Capaldi L, Wharton G, Lawrence WD, Robinson-Bostom L
Cutis 2005 Feb;75(2):118-20. PMID: 15773533
Skin manifestations associated with tumours of the brain.
Adreev VC, Petkov I
Br J Dermatol 1975 Jun;92(6):675-678. doi: 10.1111/j.1365-2133.1975.tb03148.x. PMID: 1182081

Diagnosis

Rare mimic of angiosarcoma: Erythema ab igne with reactive angiomatosis.
Johnson NM, Shvygina A, Luyimbazi DT, Grider DJ
J Cutan Pathol 2021 Oct;48(10):1298-1302. Epub 2021 Jun 24 doi: 10.1111/cup.14072. PMID: 34086363
Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis.
Li FG, Huang WB, Chen HS, Wang T, Fan YM
Int J STD AIDS 2020 Jun;31(7):699-701. Epub 2020 May 3 doi: 10.1177/0956462419900092. PMID: 32362198
Multinucleated atypia of the vulva.
Rausch D, Angermeier M, Capaldi L, Wharton G, Lawrence WD, Robinson-Bostom L
Cutis 2005 Feb;75(2):118-20. PMID: 15773533
Oral lichenoid eruption secondary to imatinib (Glivec).
Ena P, Chiarolini F, Siddi GM, Cossu A
J Dermatolog Treat 2004 Jul;15(4):253-5. doi: 10.1080/09546630410015556. PMID: 15764042
Poikiloderma of Theresa Kindler: report of a case with ultrastructural study, and review of the literature.
Hovnanian A, Blanchet-Bardon C, de Prost Y
Pediatr Dermatol 1989 Jun;6(2):82-90. doi: 10.1111/j.1525-1470.1989.tb01003.x. PMID: 2664739

Therapy

Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis.
Li FG, Huang WB, Chen HS, Wang T, Fan YM
Int J STD AIDS 2020 Jun;31(7):699-701. Epub 2020 May 3 doi: 10.1177/0956462419900092. PMID: 32362198
Metastatic melanoma from an unknown primary site presenting as skin-colored nodules and multiple visceral involvement.
Ghosh SK, Bandyopadhyay D, Barma KD, Basu S, Roy A
Skinmed 2012 Nov-Dec;10(6):396-9. PMID: 23346671
Oral lichenoid eruption secondary to imatinib (Glivec).
Ena P, Chiarolini F, Siddi GM, Cossu A
J Dermatolog Treat 2004 Jul;15(4):253-5. doi: 10.1080/09546630410015556. PMID: 15764042

Prognosis

Biallelic TUFT1 variants cause woolly hair, superficial skin fragility and desmosomal defects.
Jackson A, Moss C, Chandler KE, Balboa PL, Bageta ML, Petrof G, Martinez AE, Liu L, Guy A, Mellerio JE, Lee JYW, Ogboli M, Ryan G; Genomics England Research Consortium, McGrath JA, Banka S
Br J Dermatol 2023 Jan 23;188(1):75-83. doi: 10.1093/bjd/ljac026. PMID: 36689522
Metastatic melanoma from an unknown primary site presenting as skin-colored nodules and multiple visceral involvement.
Ghosh SK, Bandyopadhyay D, Barma KD, Basu S, Roy A
Skinmed 2012 Nov-Dec;10(6):396-9. PMID: 23346671
Multinucleated atypia of the vulva.
Rausch D, Angermeier M, Capaldi L, Wharton G, Lawrence WD, Robinson-Bostom L
Cutis 2005 Feb;75(2):118-20. PMID: 15773533
A novel mutation in the 2B domain of keratin 2e causing ichthyosis bullosa of Siemens.
Irvine AD, Smith FJ, Shum KW, Williams HC, McLean WH
Clin Exp Dermatol 2000 Nov;25(8):648-51. doi: 10.1046/j.1365-2230.2000.00728.x. PMID: 11167982
Skin manifestations associated with tumours of the brain.
Adreev VC, Petkov I
Br J Dermatol 1975 Jun;92(6):675-678. doi: 10.1111/j.1365-2133.1975.tb03148.x. PMID: 1182081

Clinical prediction guides

Biallelic TUFT1 variants cause woolly hair, superficial skin fragility and desmosomal defects.
Jackson A, Moss C, Chandler KE, Balboa PL, Bageta ML, Petrof G, Martinez AE, Liu L, Guy A, Mellerio JE, Lee JYW, Ogboli M, Ryan G; Genomics England Research Consortium, McGrath JA, Banka S
Br J Dermatol 2023 Jan 23;188(1):75-83. doi: 10.1093/bjd/ljac026. PMID: 36689522
Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis.
Li FG, Huang WB, Chen HS, Wang T, Fan YM
Int J STD AIDS 2020 Jun;31(7):699-701. Epub 2020 May 3 doi: 10.1177/0956462419900092. PMID: 32362198
Palm tissue displaying a polyclonal autoimmune response in patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America.
Abreu Velez AM, Howard MS, Hashimoto T
Eur J Dermatol 2010 Jan-Feb;20(1):74-81. Epub 2009 Nov 4 doi: 10.1684/ejd.2010.0834. PMID: 19889592
A novel mutation in the 2B domain of keratin 2e causing ichthyosis bullosa of Siemens.
Irvine AD, Smith FJ, Shum KW, Williams HC, McLean WH
Clin Exp Dermatol 2000 Nov;25(8):648-51. doi: 10.1046/j.1365-2230.2000.00728.x. PMID: 11167982
Skin manifestations associated with tumours of the brain.
Adreev VC, Petkov I
Br J Dermatol 1975 Jun;92(6):675-678. doi: 10.1111/j.1365-2133.1975.tb03148.x. PMID: 1182081

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