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Ptosis-vocal cord paralysis syndrome

MedGen UID:
349807
•Concept ID:
C1860403
•
Disease or Syndrome
Synonyms: Congenital bilateral recurrent nerve paralysis and ptosis; Ptosis vocal cord paralysis; Tucker syndrome; VOCAL CORD PARALYSIS AND PTOSIS
SNOMED CT: Ptosis and vocal cord paralysis syndrome (771263004); Tucker syndrome (771263004)
 
Monarch Initiative: MONDO:0008665
OMIM®: 193240
Orphanet: ORPHA2997

Definition

A rare hereditary disorder with the combination of congenital bilateral recurrent laryngeal nerve paralysis and congenital bilateral ptosis. There have been no further descriptions in the literature since 1983. [from SNOMEDCT_US]

Clinical features

From HPO
Vocal cord paralysis
MedGen UID:
53047
•Concept ID:
C0042928
•
Disease or Syndrome
A loss of the ability to move the vocal folds.
See: Feature record | Search on this feature
Bilateral ptosis
MedGen UID:
356120
•Concept ID:
C1865916
•
Disease or Syndrome
See: Feature record | Search on this feature
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Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPtosis-vocal cord paralysis syndrome
Follow this link to review classifications for Ptosis-vocal cord paralysis syndrome in Orphanet.

Professional guidelines

PubMed

Spasticity: pathophysiology, evaluation and management.
Kheder A, Nair KP
Pract Neurol 2012 Oct;12(5):289-98. doi: 10.1136/practneurol-2011-000155. PMID: 22976059
Chronic symptoms after subtotal or partial oesophagectomy: diagnosis and treatment.
Lerut TE, van Lanschot JJ
Best Pract Res Clin Gastroenterol 2004 Oct;18(5):901-15. doi: 10.1016/j.bpg.2004.06.029. PMID: 15494285
Prevention and management of complications of airway surgery in children.
Yellon RF
Paediatr Anaesth 2004 Jan;14(1):107-11. doi: 10.1046/j.1460-9592.2003.01199.x. PMID: 14717883

Recent clinical studies

Etiology

Endoscopic percutaneous suture lateralization with syringe needles for neonatal bilateral vocal cord paralysis.
Zhao X, Yan S, Yang H, Li L, Pan H
Am J Otolaryngol 2022 May-Jun;43(3):103380. Epub 2022 Feb 2 doi: 10.1016/j.amjoto.2022.103380. PMID: 35256206
Posterior cord syndrome: Demographics and rehabilitation outcomes.
McKinley W, Hills A, Sima A
J Spinal Cord Med 2021 Mar;44(2):241-246. Epub 2019 Apr 2 doi: 10.1080/10790268.2019.1585135. PMID: 30939076Free PMC Article
Acute infectious myelopathies.
Isada CM, Miller R
Curr Opin Infect Dis 2020 Jun;33(3):251-258. doi: 10.1097/QCO.0000000000000650. PMID: 32332224
Infectious Myelopathies.
Grill MF
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. PMID: 29613895
Rehabilitation of Guillain-Barré syndrome.
Meythaler JM
Arch Phys Med Rehabil 1997 Aug;78(8):872-9. doi: 10.1016/s0003-9993(97)90203-3. PMID: 9344309

Diagnosis

Cardiovascular Hoarseness (Ortner's Syndrome): A Pictorial Review.
Kheok SW, Salkade PR, Bangaragiri A, Koh NSY, Chen RC
Curr Probl Diagn Radiol 2021 Sep-Oct;50(5):749-754. Epub 2020 Sep 23 doi: 10.1067/j.cpradiol.2020.09.015. PMID: 33036813
Posterior cord syndrome: Demographics and rehabilitation outcomes.
McKinley W, Hills A, Sima A
J Spinal Cord Med 2021 Mar;44(2):241-246. Epub 2019 Apr 2 doi: 10.1080/10790268.2019.1585135. PMID: 30939076Free PMC Article
Mills' syndrome revisited.
Jaiser SR, Mitra D, Williams TL, Baker MR
J Neurol 2019 Mar;266(3):667-679. Epub 2019 Jan 10 doi: 10.1007/s00415-019-09186-3. PMID: 30631918Free PMC Article
Spasticity: pathophysiology, evaluation and management.
Kheder A, Nair KP
Pract Neurol 2012 Oct;12(5):289-98. doi: 10.1136/practneurol-2011-000155. PMID: 22976059
Vocal cord paralysis.
Grundfast KM, Harley E
Otolaryngol Clin North Am 1989 Jun;22(3):569-97. PMID: 2657584

Therapy

Endoscopic percutaneous suture lateralization with syringe needles for neonatal bilateral vocal cord paralysis.
Zhao X, Yan S, Yang H, Li L, Pan H
Am J Otolaryngol 2022 May-Jun;43(3):103380. Epub 2022 Feb 2 doi: 10.1016/j.amjoto.2022.103380. PMID: 35256206
Vocal cord paralysis following lithium button battery ingestion in children.
Duan Q, Zhang F, Wang G, Wang H, Li H, Zhao J, Zhang J, Ni X
Eur J Pediatr 2021 Apr;180(4):1059-1066. Epub 2020 Oct 13 doi: 10.1007/s00431-020-03830-1. PMID: 33048238
Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity.
Giordano F, Zicca A, Barba C, Guerrini R, Genitori L
Epilepsia 2017 Apr;58 Suppl 1:85-90. doi: 10.1111/epi.13678. PMID: 28386925
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Rehabilitation of Guillain-Barré syndrome.
Meythaler JM
Arch Phys Med Rehabil 1997 Aug;78(8):872-9. doi: 10.1016/s0003-9993(97)90203-3. PMID: 9344309

Prognosis

Posterior cord syndrome: Demographics and rehabilitation outcomes.
McKinley W, Hills A, Sima A
J Spinal Cord Med 2021 Mar;44(2):241-246. Epub 2019 Apr 2 doi: 10.1080/10790268.2019.1585135. PMID: 30939076Free PMC Article
Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury: Origins and Guideline-Based Countermeasures.
Nash MS, Gater DR Jr
Phys Med Rehabil Clin N Am 2020 Aug;31(3):415-436. doi: 10.1016/j.pmr.2020.04.005. PMID: 32624103
Infectious Myelopathies.
Montalvo M, Cho TA
Neurol Clin 2018 Nov;36(4):789-808. doi: 10.1016/j.ncl.2018.06.001. PMID: 30366555
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Rehabilitation of Guillain-Barré syndrome.
Meythaler JM
Arch Phys Med Rehabil 1997 Aug;78(8):872-9. doi: 10.1016/s0003-9993(97)90203-3. PMID: 9344309

Clinical prediction guides

Spinal lesions caused by abusive trauma in young children.
Vinchon M, Noulé N, Toubol A, Karnoub MA
Childs Nerv Syst 2022 Dec;38(12):2349-2355. Epub 2022 Dec 13 doi: 10.1007/s00381-022-05778-z. PMID: 36512049
Louis Duménil (1823-1890), surgeon and pioneer in neurology.
Walusinski O
Rev Neurol (Paris) 2022 Apr;178(4):298-305. Epub 2021 Sep 23 doi: 10.1016/j.neurol.2021.06.011. PMID: 34565621
Posterior cord syndrome: Demographics and rehabilitation outcomes.
McKinley W, Hills A, Sima A
J Spinal Cord Med 2021 Mar;44(2):241-246. Epub 2019 Apr 2 doi: 10.1080/10790268.2019.1585135. PMID: 30939076Free PMC Article
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Rehabilitation of Guillain-Barré syndrome.
Meythaler JM
Arch Phys Med Rehabil 1997 Aug;78(8):872-9. doi: 10.1016/s0003-9993(97)90203-3. PMID: 9344309

Recent systematic reviews

The efficacy and safety of high-intensity focused ultrasound in the treatment of benign thyroid nodules: A systematic review and meta-analysis from 1990 to 2021.
Cheong CWS, Au JXY, Lim MY, Fu EW, Li H, Gan JY
Ann Acad Med Singap 2022 Feb;51(2):101-108. doi: 10.47102/annals-acadmedsg.2021260. PMID: 35224606
Efficacy of mycophenolate mofetil in the treatment of neuromyelitis optica spectrum disorders: An update systematic review and meta -analysis.
Wang Y, Ma J, Chang H, Zhang X, Yin L
Mult Scler Relat Disord 2021 Oct;55:103181. Epub 2021 Jul 31 doi: 10.1016/j.msard.2021.103181. PMID: 34365314
Prevalence of sleep-disordered breathing in people with tetraplegia-a systematic review and meta-analysis.
Graco M, McDonald L, Green SE, Jackson ML, Berlowitz DJ
Spinal Cord 2021 May;59(5):474-484. Epub 2021 Jan 14 doi: 10.1038/s41393-020-00595-0. PMID: 33446931
Paralysis Caused by Spinal Cord Injury After Posterior Fossa Surgery: A Systematic Review.
Yahanda AT, Chicoine MR
World Neurosurg 2020 Jul;139:151-157. Epub 2020 Apr 17 doi: 10.1016/j.wneu.2020.04.016. PMID: 32305599
Cardiovocal syndrome: a systematic review.
Mulpuru SK, Vasavada BC, Punukollu GK, Patel AG
Heart Lung Circ 2008 Feb;17(1):1-4. Epub 2007 Dec 4 doi: 10.1016/j.hlc.2007.04.007. PMID: 18055261

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