U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lung Soft Tissue Neoplasm

MedGen UID:
353872
•Concept ID:
C1708783
•
Neoplastic Process

Definition

A benign, intermediate, or malignant mesenchymal neoplasm that arises from the lung. [from NCI]

Professional guidelines

PubMed

Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China.
Xu C, Si L, Wang W, Li Z, Song Z, Wang Q, Liu A, Yu J, Fang W, Zhong W, Wang Z, Zhang Y, Liu J, Zhang S, Cai X, Liu A, Li W, Zhan P, Liu H, Lv T, Miao L, Min L, Chen Y, Yuan J, Wang F, Jiang Z, Lin G, Pu X, Lin R, Liu W, Rao C, Lv D, Yu Z, Lei L, Li X, Tang C, Zhou C, Zhang J, Xue J, Guo H, Chu Q, Meng R, Wu J, Zhang R, Hu X, Zhou J, Zhu Z, Li Y, Qiu H, Xia F, Lu Y, Chen X, Ge R, Dai E, Han Y, Pan W, Luo J, Jia H, Dong X, Pang F, Wang K, Wang L, Zhu Y, Xie Y, Lin X, Cai J, Wei J, Lan F, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Wan B, Lv D, Wei Q, Kang J, Zhang J, Zhang C, Yu G, Ou J, Shi L, Li Z, Liu Z, Liu J, Yang N, Wu L, Wang H, Jin G, Yang L, Wang G, Fang M, Fang Y, Li Y, Wang X, Zhang Y, Ma S, Wang B, Zhang X, Song Y, Lu Y
Thorac Cancer 2022 Nov;13(21):3084-3097. Epub 2022 Sep 20 doi: 10.1111/1759-7714.14644. PMID: 36127731Free PMC Article
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article
Multidisciplinary Management of Oligometastatic Soft Tissue Sarcoma.
Grilley-Olson JE, Webber NP, Demos DS, Christensen JD, Kirsch DG
Am Soc Clin Oncol Educ Book 2018 May 23;38:939-948. doi: 10.1200/EDBK_200573. PMID: 30231386

Recent clinical studies

Etiology

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
CIC-DUX4 sarcomas.
Brahmi M, Vanacker H, Macagno N, Tirode F, Dufresne A
Curr Opin Oncol 2022 Jul 1;34(4):342-347. Epub 2022 Jun 22 doi: 10.1097/CCO.0000000000000855. PMID: 35730520
The Impact of Pazopanib on the Cardiovascular System.
Justice CN, Derbala MH, Baich TM, Kempton AN, Guo AS, Ho TH, Smith SA
J Cardiovasc Pharmacol Ther 2018 Sep;23(5):387-398. Epub 2018 Apr 29 doi: 10.1177/1074248418769612. PMID: 29706106Free PMC Article
Current Technique and Application of Percutaneous Cryotherapy.
Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article

Diagnosis

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Musculoskeletal Metastasis From Soft-tissue Sarcomas: A Review of the Literature.
Pretell-Mazzini J, Seldon CS, D'Amato G, Subhawong TK
J Am Acad Orthop Surg 2022 Jun 1;30(11):493-503. Epub 2022 Mar 22 doi: 10.5435/JAAOS-D-21-00944. PMID: 35320120
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Therapy

Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial.
de Bono JS, Mehra N, Scagliotti GV, Castro E, Dorff T, Stirling A, Stenzl A, Fleming MT, Higano CS, Saad F, Buttigliero C, van Oort IM, Laird AD, Mata M, Chen HC, Healy CG, Czibere A, Fizazi K
Lancet Oncol 2021 Sep;22(9):1250-1264. Epub 2021 Aug 10 doi: 10.1016/S1470-2045(21)00376-4. PMID: 34388386
Current Technique and Application of Percutaneous Cryotherapy.
Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588
Ridaforolimus.
Drugs R D 2010;10(3):165-78. doi: 10.2165/11586010-000000000-00000. PMID: 20945947Free PMC Article
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Prognosis

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Basic Knowledge in Soft Tissue Sarcoma.
Bourcier K, Le Cesne A, Tselikas L, Adam J, Mir O, Honore C, de Baere T
Cardiovasc Intervent Radiol 2019 Sep;42(9):1255-1261. Epub 2019 Jun 24 doi: 10.1007/s00270-019-02259-w. PMID: 31236647
Current Technique and Application of Percutaneous Cryotherapy.
Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Liposarcoma.
Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Clinical prediction guides

Popliteal Fossa Sarcomas.
Erdogan O, Çeli K A, Yildirim ANT, Tekçe E, Altun G, Demi Röz S, Güler Y, Ozkan K, Gurkan V
Acta Chir Orthop Traumatol Cech 2023;90(3):181-187. PMID: 37395425
Musculoskeletal Metastasis From Soft-tissue Sarcomas: A Review of the Literature.
Pretell-Mazzini J, Seldon CS, D'Amato G, Subhawong TK
J Am Acad Orthop Surg 2022 Jun 1;30(11):493-503. Epub 2022 Mar 22 doi: 10.5435/JAAOS-D-21-00944. PMID: 35320120
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR
Am J Surg Pathol 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. PMID: 29300189Free PMC Article
Soft tissue metastases in lung cancer: a review of the literature.
Perisano C, Spinelli MS, Graci C, Scaramuzzo L, Marzetti E, Barone C, Fabbriciani C, Maccauro G
Eur Rev Med Pharmacol Sci 2012 Dec;16(14):1908-14. PMID: 23242715
Metallothioneins and cancer.
Eckschlager T, Adam V, Hrabeta J, Figova K, Kizek R
Curr Protein Pept Sci 2009 Aug;10(4):360-75. doi: 10.2174/138920309788922243. PMID: 19689357

Recent systematic reviews

Clinical outcomes of brain metastasectomy from soft tissue and bone sarcomas: a systematic review.
Wang Y, Delisle M, Smith D, Alshamsan B, Srikanthan A
Int J Clin Oncol 2022 Nov;27(11):1767-1779. Epub 2022 Aug 22 doi: 10.1007/s10147-022-02227-4. PMID: 35994183
Metastasis to the oral and maxillofacial region. A systematic review.
Labrador AJP, Marin NRG, Valdez LHM, Sanchez KBT, Zabarburu W, Ibazetta KAR, Garcia AER, Cabezas DM, Romero L, Conte AM, Wright JM
J Stomatol Oral Maxillofac Surg 2022 Oct;123(5):e474-e483. Epub 2021 Dec 20 doi: 10.1016/j.jormas.2021.12.009. PMID: 34933137
A systematic review and meta-analysis of outcomes after acute limb ischemia in patients with cancer.
Govsyeyev N, Malgor RD, Hoffman C, Harroun N, Sturman E, Al-Musawi M, Malgor EA, Jacobs DL, Nehler M
J Vasc Surg 2021 Sep;74(3):1033-1040.e1. Epub 2021 Apr 24 doi: 10.1016/j.jvs.2021.03.058. PMID: 33905869
High frequency of lobular breast cancer in distant metastases to the orbit.
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547Free PMC Article
Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials.
Santoni M, Conti A, De Giorgi U, Iacovelli R, Pantano F, Burattini L, Muzzonigro G, Berardi R, Santini D, Cascinu S
Int J Cancer 2014 Aug 15;135(4):763-73. Epub 2013 Nov 18 doi: 10.1002/ijc.28544. PMID: 24127298

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...