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Small Intestinal Villous Adenoma

MedGen UID:
354183
Concept ID:
C1710115
Neoplastic Process

Definition

A neoplasm that arises from the glandular epithelium of the small intestine. It is characterized by a villous architectural pattern. The neoplastic glandular cells have dysplastic features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall Intestinal Villous Adenoma

Professional guidelines

PubMed

Gluck N, Strul H, Rozner G, Leshno M, Santo E
Gastrointest Endosc 2015 Apr;81(4):960-6. Epub 2014 Oct 24 doi: 10.1016/j.gie.2014.08.029. PMID: 25440680
Martín-Lorenzo JG, Torralba-Martinez A, Lirón-Ruiz R, Flores-Pastor B, Miguel-Perelló J, Aguilar-Jimenez J, Aguayo-Albasini JL
Int J Colorectal Dis 2004 Jan;19(1):68-72. Epub 2003 Jun 28 doi: 10.1007/s00384-003-0514-z. PMID: 12838363
Reddy RR, Schuman BM, Priest RJ
J Clin Gastroenterol 1981 Jun;3(2):139-47. doi: 10.1097/00004836-198106000-00007. PMID: 7240690

Recent clinical studies

Etiology

Emilsson L, Semrad C, Lebwohl B, Green PHR, Ludvigsson JF
Gastroenterology 2020 Nov;159(5):1686-1694.e2. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.07.007. PMID: 32679218
Vleugels JLA, Hazewinkel Y, Fockens P, Dekker E
Gastrointest Endosc 2017 Jun;85(6):1169-1176.e1. Epub 2016 Dec 23 doi: 10.1016/j.gie.2016.12.014. PMID: 28024986
Wittekind C, Tannapfel A
Langenbecks Arch Surg 2001 Apr;386(3):172-5. doi: 10.1007/s004230100234. PMID: 11382317
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560

Diagnosis

Emilsson L, Semrad C, Lebwohl B, Green PHR, Ludvigsson JF
Gastroenterology 2020 Nov;159(5):1686-1694.e2. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.07.007. PMID: 32679218
Mitra S, Ayyanar P, Kaur G
Int J Surg Pathol 2020 Feb;28(1):4-12. Epub 2019 Aug 13 doi: 10.1177/1066896919868527. PMID: 31409167
Vleugels JLA, Hazewinkel Y, Fockens P, Dekker E
Gastrointest Endosc 2017 Jun;85(6):1169-1176.e1. Epub 2016 Dec 23 doi: 10.1016/j.gie.2016.12.014. PMID: 28024986
Martín-Lorenzo JG, Torralba-Martinez A, Lirón-Ruiz R, Flores-Pastor B, Miguel-Perelló J, Aguilar-Jimenez J, Aguayo-Albasini JL
Int J Colorectal Dis 2004 Jan;19(1):68-72. Epub 2003 Jun 28 doi: 10.1007/s00384-003-0514-z. PMID: 12838363
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Therapy

Emilsson L, Semrad C, Lebwohl B, Green PHR, Ludvigsson JF
Gastroenterology 2020 Nov;159(5):1686-1694.e2. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.07.007. PMID: 32679218
Nayak A, Depasquale B, Vergara N, Guzzo TA, Lal P
Int J Surg Pathol 2019 Jun;27(4):450-456. Epub 2019 Jan 31 doi: 10.1177/1066896919826708. PMID: 30701999
Thomson M, Venkatesh K, Elmalik K, van der Veer W, Jaacobs M
World J Gastroenterol 2010 Jan 7;16(1):56-62. doi: 10.3748/wjg.v16.i1.56. PMID: 20039449Free PMC Article
Saini SD, Kim HM, Schoenfeld P
Gastrointest Endosc 2006 Oct;64(4):614-26. doi: 10.1016/j.gie.2006.06.057. PMID: 16996358
Asbun HJ, Rossi RL, Munson JL
Arch Surg 1993 May;128(5):515-20. doi: 10.1001/archsurg.1993.01420170045006. PMID: 8098205

Prognosis

Del Rio P, Cozzani F, Viani L, Nisi P, Rossini M, Sianesi M
Ann Ital Chir 2015;86:396-405. PMID: 26567607
Motton G, Veraldi GF, Fracastoro G, Ricci F, Laterza E, Dorrucci V, Cordiano C
Hepatogastroenterology 1996 Mar-Apr;43(8):448-55. PMID: 8714243
Asbun HJ, Rossi RL, Munson JL
Arch Surg 1993 May;128(5):515-20. doi: 10.1001/archsurg.1993.01420170045006. PMID: 8098205
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560
Day DW
Scand J Gastroenterol Suppl 1984;104:99-107. PMID: 6597553

Clinical prediction guides

Emilsson L, Semrad C, Lebwohl B, Green PHR, Ludvigsson JF
Gastroenterology 2020 Nov;159(5):1686-1694.e2. Epub 2020 Jul 15 doi: 10.1053/j.gastro.2020.07.007. PMID: 32679218
Yoshida M, Shimoda T, Abe M, Kakushima N, Kawata N, Takizawa K, Ono H, Sugino T
Pathol Int 2019 Jul;69(7):398-406. Epub 2019 Jul 21 doi: 10.1111/pin.12829. PMID: 31328367
Vleugels JLA, Hazewinkel Y, Fockens P, Dekker E
Gastrointest Endosc 2017 Jun;85(6):1169-1176.e1. Epub 2016 Dec 23 doi: 10.1016/j.gie.2016.12.014. PMID: 28024986
Ogata S, Shimizu K, Nakanishi K
Ann Diagn Pathol 2015 Dec;19(6):414-7. Epub 2015 Oct 21 doi: 10.1016/j.anndiagpath.2015.10.004. PMID: 26597024
Yoo TW, Park DI, Kim YH, Kim HS, Kim WH, Kim TI, Kim HJ, Yang SK, Byeon JS, Lee MS, Jung IK, Chung MK, Jung SA, Jeen YT, Choi JH, Choi H, Han DS, Song JS
Hepatogastroenterology 2007 Mar;54(74):418-21. PMID: 17523287

Recent systematic reviews

Vleugels JLA, Hazewinkel Y, Fockens P, Dekker E
Gastrointest Endosc 2017 Jun;85(6):1169-1176.e1. Epub 2016 Dec 23 doi: 10.1016/j.gie.2016.12.014. PMID: 28024986
Saini SD, Kim HM, Schoenfeld P
Gastrointest Endosc 2006 Oct;64(4):614-26. doi: 10.1016/j.gie.2006.06.057. PMID: 16996358

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