U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Basal cell nevi

MedGen UID:
354714
•Concept ID:
C1862314
•
Neoplastic Process

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBasal cell nevi

Professional guidelines

PubMed

S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675
Guidelines of care for the management of cutaneous squamous cell carcinoma.
Work Group; Invited Reviewers, Kim JYS, Kozlow JH, Mittal B, Moyer J, Olenecki T, Rodgers P
J Am Acad Dermatol 2018 Mar;78(3):560-578. Epub 2018 Jan 10 doi: 10.1016/j.jaad.2017.10.007. PMID: 29331386Free PMC Article
Guidelines of care for the management of basal cell carcinoma.
Work Group; Invited Reviewers, Kim JYS, Kozlow JH, Mittal B, Moyer J, Olencki T, Rodgers P
J Am Acad Dermatol 2018 Mar;78(3):540-559. Epub 2018 Jan 10 doi: 10.1016/j.jaad.2017.10.006. PMID: 29331385

Recent clinical studies

Etiology

Microdeletion of 9q22.3: A patient with minimal deletion size associated with a severe phenotype.
Ewing AD, Cheetham SW, McGill JJ, Sharkey M, Walker R, West JA, West MJ, Summers KM
Am J Med Genet A 2021 Jul;185(7):2070-2083. Epub 2021 May 7 doi: 10.1002/ajmg.a.62224. PMID: 33960642Free PMC Article
Odontogenic keratocysts in the Basal Cell Nevus (Gorlin-Goltz) Syndrome associated with paresthesia of the lower jaw: Case report, retrospective analysis of a representative Czech cohort and recommendations for the early diagnosis.
Hubacek M, Kripnerova T, Nemcikova M, Krepelová A, Puchmajerova A, Malikova M, Havlovicová M, Cadova J, Kodet R, Macek M Jr, Dostalova T
Neuro Endocrinol Lett 2016 Sep;37(4):269-276. PMID: 27857042
Expression of the hair stem cell-specific keratin 15 in pilar tumors of the skin.
Kanitakis J, Bourchany D, Faure M, Claudy A
Eur J Dermatol 1999 Jul-Aug;9(5):363-5. PMID: 10417438
Medulloblastoma in the nevoid basal-cell carcinoma syndrome: case reports and review of the literature.
Lacombe D, Chateil JF, Fontan D, Battin J
Genet Couns 1990;1(3-4):273-7. PMID: 2098052

Diagnosis

Odontogenic keratocysts are an important clue for diagnosing basal cell nevus syndrome.
Kaibuchi-Ando K, Takeichi T, Ito Y, Takeuchi S, Yamashita Y, Yamada M, Muro Y, Ogi T, Akiyama M
Nagoya J Med Sci 2021 May;83(2):393-396. doi: 10.18999/nagjms.83.2.393. PMID: 34239189Free PMC Article
Odontogenic keratocysts in the Basal Cell Nevus (Gorlin-Goltz) Syndrome associated with paresthesia of the lower jaw: Case report, retrospective analysis of a representative Czech cohort and recommendations for the early diagnosis.
Hubacek M, Kripnerova T, Nemcikova M, Krepelová A, Puchmajerova A, Malikova M, Havlovicová M, Cadova J, Kodet R, Macek M Jr, Dostalova T
Neuro Endocrinol Lett 2016 Sep;37(4):269-276. PMID: 27857042
Gorlin-Goltz syndrome: a rare case report.
Mohan RP, Verma S, Agarwal N, Singh U
BMJ Case Rep 2013 Jun 27;2013 doi: 10.1136/bcr-2013-010409. PMID: 23814215Free PMC Article
Sporadic Bazex-Dupré-Christol-like syndrome: early onset basal cell carcinoma, hypohidrosis, hypotrichosis, and prominent milia.
Glaessl A, Hohenlautner U, Landthaler M, Vogt T
Dermatol Surg 2000 Feb;26(2):152-4. doi: 10.1046/j.1524-4725.2000.99146.x. PMID: 10691946
Medulloblastoma in the nevoid basal-cell carcinoma syndrome: case reports and review of the literature.
Lacombe D, Chateil JF, Fontan D, Battin J
Genet Couns 1990;1(3-4):273-7. PMID: 2098052

Therapy

Generalized melanoses and nonmelanotic pigmentations of the head and neck.
Marlette RH
J Am Dent Assoc 1975 Jan;90(1):141-7. doi: 10.14219/jada.archive.1975.0031. PMID: 803220

Prognosis

Odontogenic keratocysts are an important clue for diagnosing basal cell nevus syndrome.
Kaibuchi-Ando K, Takeichi T, Ito Y, Takeuchi S, Yamashita Y, Yamada M, Muro Y, Ogi T, Akiyama M
Nagoya J Med Sci 2021 May;83(2):393-396. doi: 10.18999/nagjms.83.2.393. PMID: 34239189Free PMC Article
Early diagnosis of Gorlin-Goltz syndrome: case report.
Casaroto AR, Loures DC, Moreschi E, Veltrini VC, Trento CL, Gottardo VD, Lara VS
Head Face Med 2011 Jan 25;7:2. doi: 10.1186/1746-160X-7-2. PMID: 21266031Free PMC Article
Ovarian fibromas in pediatric patients with basal cell nevus (Gorlin) syndrome.
Ball A, Wenning J, Van Eyk N
J Pediatr Adolesc Gynecol 2011 Feb;24(1):e5-7. doi: 10.1016/j.jpag.2010.07.005. PMID: 20817576
Medulloblastoma in the nevoid basal-cell carcinoma syndrome: case reports and review of the literature.
Lacombe D, Chateil JF, Fontan D, Battin J
Genet Couns 1990;1(3-4):273-7. PMID: 2098052

Clinical prediction guides

Expression of the hair stem cell-specific keratin 15 in pilar tumors of the skin.
Kanitakis J, Bourchany D, Faure M, Claudy A
Eur J Dermatol 1999 Jul-Aug;9(5):363-5. PMID: 10417438
The Bazex-Dupré-Christol syndrome.
Goeteyn M, Geerts ML, Kint A, De Weert J
Arch Dermatol 1994 Mar;130(3):337-42. PMID: 8129412
Familial basal cell nevus syndrome.
Lorenz R, Fuhrmann W
Hum Genet 1978 Oct 31;44(2):153-63. doi: 10.1007/BF00295408. PMID: 730159

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...