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Suprabasal acantholysis

MedGen UID:
356990
•Concept ID:
C1868504
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuprabasal acantholysis

Professional guidelines

PubMed

Hypotonic, Acidic Oxidizing Solution Containing Hypochlorous Acid (HClO) as a Potential Treatment of Hailey-Hailey Disease.
Cialfi S, Calabro S, Franchitto M, Zonfrilli A, Screpanti I, Talora C
Molecules 2019 Dec 4;24(24) doi: 10.3390/molecules24244427. PMID: 31817098Free PMC Article

Recent clinical studies

Etiology

Pemphigus vegetans of the folds (intertriginous areas).
Ruocco V, Ruocco E, Caccavale S, Gambardella A, Lo Schiavo A
Clin Dermatol 2015 Jul-Aug;33(4):471-6. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.011. PMID: 26051064
Hailey-Hailey disease: A fold (intertriginous) dermatosis.
Engin B, Kutlubay Z, Çelik U, Serdaroğlu S, Tüzün Y
Clin Dermatol 2015 Jul-Aug;33(4):452-5. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.006. PMID: 26051060
The spectrum of reticulate pigment disorders of the skin revisited.
Müller CS, Tremezaygues L, Pföhler C, Vogt T
Eur J Dermatol 2012 Sep-Oct;22(5):596-604. doi: 10.1684/ejd.2012.1829. PMID: 23018017
Pemphigus vulgaris: recent advances in our understanding of its pathogenesis.
Femiano F
Minerva Stomatol 2007 Apr;56(4):215-23. PMID: 17452959
Ocular pemphigus.
Daoud YJ, Cervantes R, Foster CS, Ahmed AR
J Am Acad Dermatol 2005 Oct;53(4):585-90. doi: 10.1016/j.jaad.2005.02.061. PMID: 16198777

Diagnosis

Acantholytic Dyskeratosis Post-COVID Vaccination.
Yang K, Prussick L, Hartman R, Mahalingam M
Am J Dermatopathol 2022 Jun 1;44(6):e61-e63. Epub 2022 Feb 15 doi: 10.1097/DAD.0000000000002150. PMID: 35170477
Pemphigus vegetans of the folds (intertriginous areas).
Ruocco V, Ruocco E, Caccavale S, Gambardella A, Lo Schiavo A
Clin Dermatol 2015 Jul-Aug;33(4):471-6. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.011. PMID: 26051064
The spectrum of reticulate pigment disorders of the skin revisited.
Müller CS, Tremezaygues L, Pföhler C, Vogt T
Eur J Dermatol 2012 Sep-Oct;22(5):596-604. doi: 10.1684/ejd.2012.1829. PMID: 23018017
Ocular pemphigus.
Daoud YJ, Cervantes R, Foster CS, Ahmed AR
J Am Acad Dermatol 2005 Oct;53(4):585-90. doi: 10.1016/j.jaad.2005.02.061. PMID: 16198777
Sensitivity and specificity of clinical, histologic, and immunologic features in the diagnosis of paraneoplastic pemphigus.
Joly P, Richard C, Gilbert D, Courville P, Chosidow O, Roujeau JC, Beylot-Barry M, D'incan M, Martel P, Lauret P, Tron F
J Am Acad Dermatol 2000 Oct;43(4):619-26. doi: 10.1067/mjd.2000.107488. PMID: 11004616

Therapy

Novel Therapies for Pemphigus Vulgaris.
Altman EM
Am J Clin Dermatol 2020 Dec;21(6):765-782. doi: 10.1007/s40257-020-00544-w. PMID: 32860200
Pemphigus vegetans of the folds (intertriginous areas).
Ruocco V, Ruocco E, Caccavale S, Gambardella A, Lo Schiavo A
Clin Dermatol 2015 Jul-Aug;33(4):471-6. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.011. PMID: 26051064
Hailey-Hailey disease: A fold (intertriginous) dermatosis.
Engin B, Kutlubay Z, Çelik U, Serdaroğlu S, Tüzün Y
Clin Dermatol 2015 Jul-Aug;33(4):452-5. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.006. PMID: 26051060
Paraneoplastic pemphigus.
Zhu X, Zhang B
J Dermatol 2007 Aug;34(8):503-11. doi: 10.1111/j.1346-8138.2007.00322.x. PMID: 17683379
Ocular pemphigus.
Daoud YJ, Cervantes R, Foster CS, Ahmed AR
J Am Acad Dermatol 2005 Oct;53(4):585-90. doi: 10.1016/j.jaad.2005.02.061. PMID: 16198777

Prognosis

Grover's Disease in a Kidney Transplant Recipient.
Kirincich J, Lončarić D, Bukvić Mokos Z, Bašić-Jukić N
Acta Dermatovenerol Croat 2019 Sep;27(3):192-194. PMID: 31542066
The Incidence of Acantholysis in Pityriasis Rubra Pilaris-Histopathological Study Using Multiple-Step Sections and Clinicopathologic Correlations.
Avitan-Hersh E, Bergman R
Am J Dermatopathol 2015 Oct;37(10):755-8. doi: 10.1097/DAD.0000000000000346. PMID: 26381023
Pemphigus vegetans of the folds (intertriginous areas).
Ruocco V, Ruocco E, Caccavale S, Gambardella A, Lo Schiavo A
Clin Dermatol 2015 Jul-Aug;33(4):471-6. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.011. PMID: 26051064
Hailey-Hailey disease: A fold (intertriginous) dermatosis.
Engin B, Kutlubay Z, Çelik U, Serdaroğlu S, Tüzün Y
Clin Dermatol 2015 Jul-Aug;33(4):452-5. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.006. PMID: 26051060
Warty dyskeratoma of the vulva.
Duray PH, Merino MJ, Axiotis C
Int J Gynecol Pathol 1983;2(3):286-93. doi: 10.1097/00004347-198303000-00006. PMID: 6642851

Clinical prediction guides

Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody-negative pemphigus vulgaris.
Chernyavsky A, Amber KT, Agnoletti AF, Wang C, Grando SA
J Biol Chem 2019 Mar 22;294(12):4520-4528. Epub 2019 Jan 28 doi: 10.1074/jbc.RA118.006743. PMID: 30692201Free PMC Article
Hailey-Hailey disease: A fold (intertriginous) dermatosis.
Engin B, Kutlubay Z, Çelik U, Serdaroğlu S, Tüzün Y
Clin Dermatol 2015 Jul-Aug;33(4):452-5. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.006. PMID: 26051060
The spectrum of reticulate pigment disorders of the skin revisited.
Müller CS, Tremezaygues L, Pföhler C, Vogt T
Eur J Dermatol 2012 Sep-Oct;22(5):596-604. doi: 10.1684/ejd.2012.1829. PMID: 23018017
Ocular pemphigus.
Daoud YJ, Cervantes R, Foster CS, Ahmed AR
J Am Acad Dermatol 2005 Oct;53(4):585-90. doi: 10.1016/j.jaad.2005.02.061. PMID: 16198777
Histologic features of paraneoplastic pemphigus.
Horn TD, Anhalt GJ
Arch Dermatol 1992 Aug;128(8):1091-5. PMID: 1497365

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