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Anuria

MedGen UID:
358
Concept ID:
C0003460
Disease or Syndrome
Synonym: Anurias
SNOMED CT: Passes no urine (2472002); Anuria (2472002)
 
HPO: HP:0100519
Monarch Initiative: MONDO:0002476

Definition

Absence of urine, clinically classified as below 50ml/day. [from HPO]

Conditions with this feature

Hemolytic uremic syndrome, atypical, susceptibility to, 1
MedGen UID:
412743
Concept ID:
C2749604
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Atypical hemolytic-uremic syndrome with thrombomodulin anomaly
MedGen UID:
414541
Concept ID:
C2752036
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Atypical hemolytic-uremic syndrome with C3 anomaly
MedGen UID:
442875
Concept ID:
C2752037
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Atypical hemolytic-uremic syndrome with B factor anomaly
MedGen UID:
416691
Concept ID:
C2752038
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Atypical hemolytic-uremic syndrome with I factor anomaly
MedGen UID:
414542
Concept ID:
C2752039
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Atypical hemolytic-uremic syndrome with MCP/CD46 anomaly
MedGen UID:
414167
Concept ID:
C2752040
Finding
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. The onset of atypical HUS (aHUS) ranges from the neonatal period to adulthood. Genetic aHUS accounts for an estimated 60% of all aHUS. Individuals with genetic aHUS frequently experience relapse even after complete recovery following the presenting episode; 60% of genetic aHUS progresses to end-stage renal disease (ESRD).
Megacystis-microcolon-intestinal hypoperistalsis syndrome 2
MedGen UID:
1788773
Concept ID:
C5543476
Disease or Syndrome
Megacystis-microcolon-intestinal hypoperistalsis syndrome-2 (MMIHS2) is characterized by prenatal bladder enlargement, neonatal functional gastrointestinal obstruction, and chronic dependence on total parenteral nutrition and urinary catheterization. The majority of cases have a fatal outcome due to malnutrition and sepsis, followed by multiorgan failure (summary by Wang et al., 2019). For a discussion of genetic heterogeneity of MMIHS, see 249210.
Renal tubular dysgenesis of genetic origin
MedGen UID:
1826125
Concept ID:
C5681536
Disease or Syndrome
An instance of renal tubular dysgenesis that is caused by a modification of the individual's genome.

Professional guidelines

PubMed

Tan HJ, Jian WY, Lv C, Guo DW, Liao ZC, Xu H, Xiao Y, Schiller M, Zhuo JL, Yue SJ, Yao RJ, Deng HW, Xiao HM
Prenat Diagn 2024 Feb;44(2):167-171. Epub 2023 Sep 25 doi: 10.1002/pd.6443. PMID: 37749763
Haycock GB
Semin Neonatol 2003 Aug;8(4):325-34. doi: 10.1016/S1084-2756(03)00044-7. PMID: 15001136
Tóth-Heyn P, Drukker A, Guignard JP
Pediatr Nephrol 2000 Mar;14(3):227-39. doi: 10.1007/s004670050048. PMID: 10752764

Recent clinical studies

Etiology

Rossiter A, La A, Koyner JL, Forni LG
Crit Rev Clin Lab Sci 2024 Jan;61(1):23-44. Epub 2023 Sep 5 doi: 10.1080/10408363.2023.2242481. PMID: 37668397
Habeebullah, Aga S, Khatri S, Bajeer IA, Sultan S, Lanewala AA
Urolithiasis 2023 Mar 16;51(1):51. doi: 10.1007/s00240-023-01429-3. PMID: 36928425
Tabinor M, Davies SJ
Curr Opin Nephrol Hypertens 2018 Nov;27(6):406-412. doi: 10.1097/MNH.0000000000000445. PMID: 30063488
Kamel MH, Gardner R, Tourchi A, Tart K, Raheem O, Houston B, Bissada N, Davis R
Int Urol Nephrol 2017 Jun;49(6):917-926. Epub 2017 Mar 7 doi: 10.1007/s11255-017-1562-6. PMID: 28265966
Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, Mujais S
J Am Soc Nephrol 2002 May;13(5):1307-1320. doi: 10.1681/ASN.V1351307. PMID: 11961019

Diagnosis

Galarza Barrachina L, Colinas Fernández L, Martín Bermúdez R, Fernández Galilea A, Martín-Villén L
Med Intensiva (Engl Ed) 2023 Nov;47(11):658-667. doi: 10.1016/j.medine.2023.06.008. PMID: 38783747
Kamel MH, Gardner R, Tourchi A, Tart K, Raheem O, Houston B, Bissada N, Davis R
Int Urol Nephrol 2017 Jun;49(6):917-926. Epub 2017 Mar 7 doi: 10.1007/s11255-017-1562-6. PMID: 28265966
Ahmad R, Natiq M, Aziz M
J Coll Physicians Surg Pak 2015 Oct;25 Suppl 2:S97-9. doi: 10.2015/JCPSP.S9799. PMID: 26522217
Gubler MC
Pediatr Nephrol 2014 Jan;29(1):51-9. Epub 2013 May 1 doi: 10.1007/s00467-013-2480-1. PMID: 23636579
Ziegler R
J Am Soc Nephrol 2001 Feb;12 Suppl 17:S3-9. PMID: 11251025

Therapy

Atkinson MA, Jelin EB, Baschat A, Blumenfeld YJ, Chmait RH, O'Hare E, Moldenhauer JS, Zaretsky MV, Miller RS, Ruano R, Gonzalez JM, Johnson A, Mould WA, Davis JM, Hanley DF, Keiser AM, Rosner M, Miller JL
Clin Ther 2022 Aug;44(8):1161-1171. Epub 2022 Jul 30 doi: 10.1016/j.clinthera.2022.07.001. PMID: 35918190Free PMC Article
Romagnoli S, Ricci Z, Ronco C
Curr Opin Crit Care 2018 Dec;24(6):483-492. doi: 10.1097/MCC.0000000000000544. PMID: 30239411
Kamel MH, Gardner R, Tourchi A, Tart K, Raheem O, Houston B, Bissada N, Davis R
Int Urol Nephrol 2017 Jun;49(6):917-926. Epub 2017 Mar 7 doi: 10.1007/s11255-017-1562-6. PMID: 28265966
Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, Mujais S
J Am Soc Nephrol 2002 May;13(5):1307-1320. doi: 10.1681/ASN.V1351307. PMID: 11961019
Hahn RG
Acta Anaesthesiol Scand 1991 Oct;35(7):557-67. doi: 10.1111/j.1399-6576.1991.tb03348.x. PMID: 1785231

Prognosis

Sarkar S, Sinha R, Chaudhury AR, Maduwage K, Abeyagunawardena A, Bose N, Pradhan S, Bresolin NL, Garcia BA, McCulloch M
Pediatr Nephrol 2021 Dec;36(12):3829-3840. Epub 2021 Feb 9 doi: 10.1007/s00467-020-04911-x. PMID: 33559706
Lowenstein J, Grantham JJ
Kidney Int 2017 Mar;91(3):561-565. doi: 10.1016/j.kint.2016.09.052. PMID: 28202171
Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, Mujais S
J Am Soc Nephrol 2002 May;13(5):1307-1320. doi: 10.1681/ASN.V1351307. PMID: 11961019
Corrigan JJ Jr, Boineau FG
Pediatr Rev 2001 Nov;22(11):365-9. PMID: 11691946
Patwardhan VB
J Indian Med Assoc 1995 Feb;93(2):58-9, 48. PMID: 7658039

Clinical prediction guides

Galarza Barrachina L, Colinas Fernández L, Martín Bermúdez R, Fernández Galilea A, Martín-Villén L
Med Intensiva (Engl Ed) 2023 Nov;47(11):658-667. doi: 10.1016/j.medine.2023.06.008. PMID: 38783747
Sarkar S, Sinha R, Chaudhury AR, Maduwage K, Abeyagunawardena A, Bose N, Pradhan S, Bresolin NL, Garcia BA, McCulloch M
Pediatr Nephrol 2021 Dec;36(12):3829-3840. Epub 2021 Feb 9 doi: 10.1007/s00467-020-04911-x. PMID: 33559706
Lowenstein J, Grantham JJ
Kidney Int 2017 Mar;91(3):561-565. doi: 10.1016/j.kint.2016.09.052. PMID: 28202171
Gubler MC
Pediatr Nephrol 2014 Jan;29(1):51-9. Epub 2013 May 1 doi: 10.1007/s00467-013-2480-1. PMID: 23636579
Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, Mujais S
J Am Soc Nephrol 2002 May;13(5):1307-1320. doi: 10.1681/ASN.V1351307. PMID: 11961019

Recent systematic reviews

Kotepui M, Kotepui KU, Milanez GJ, Masangkay FR
BMC Infect Dis 2020 May 24;20(1):363. doi: 10.1186/s12879-020-05046-y. PMID: 32448216Free PMC Article
Tian J, Shen P, Pan K, Zhou Q
Ital J Pediatr 2019 Aug 22;45(1):108. doi: 10.1186/s13052-019-0697-8. PMID: 31439016Free PMC Article
de Holanda MI, Pôrto LC, Wagner T, Christiani LF, Palma LMP
Clin Rheumatol 2017 Dec;36(12):2859-2867. Epub 2017 Sep 13 doi: 10.1007/s10067-017-3823-2. PMID: 28905254
Kamel MH, Gardner R, Tourchi A, Tart K, Raheem O, Houston B, Bissada N, Davis R
Int Urol Nephrol 2017 Jun;49(6):917-926. Epub 2017 Mar 7 doi: 10.1007/s11255-017-1562-6. PMID: 28265966
Zhang L, Zeng X, Fu P, Wu HM
Cochrane Database Syst Rev 2014 Jun 23;2014(6):CD009120. doi: 10.1002/14651858.CD009120.pub2. PMID: 24953826Free PMC Article

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