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Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor

MedGen UID:
362651
Concept ID:
C1879314
Neoplastic Process

Definition

A Sertoli-Leydig tumor of the ovary characterized by the presence of a sarcomatoid stroma which contains primitive gonadal stromal cells. It may behave in a malignant fashion and metastasize to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPoorly Differentiated Ovarian Sertoli-Leydig Cell Tumor

Professional guidelines

PubMed

Cathro HP, Stoler MH
Hum Pathol 2005 Feb;36(2):195-201. doi: 10.1016/j.humpath.2004.11.011. PMID: 15754297

Recent clinical studies

Etiology

Wang G, Zhang R, Li C, Chen A
J Ovarian Res 2021 Nov 4;14(1):150. doi: 10.1186/s13048-021-00909-7. PMID: 34736487Free PMC Article
Guo Y, Wang J, Li Y, Wang Y
Arch Gynecol Obstet 2020 Jul;302(1):203-208. Epub 2020 May 19 doi: 10.1007/s00404-020-05588-1. PMID: 32430758
Castro BGR, Souza CP, Andrade CEMDC, Vieira MA, Andrade DAP, Reis RD
Rev Bras Ginecol Obstet 2019 Jul;41(7):440-448. Epub 2019 Jul 25 doi: 10.1055/s-0039-1693056. PMID: 31344718Free PMC Article
Durmuş Y, Kılıç Ç, Çakır C, Yüksel D, Boran N, Karalök A, Boyraz G, Turan AT
J Obstet Gynaecol Res 2019 Jul;45(7):1311-1318. Epub 2019 May 20 doi: 10.1111/jog.13977. PMID: 31106943
Gressel GM, Buza N, Pal L
Eur J Gynaecol Oncol 2017;38(2):214-220. PMID: 29953783

Diagnosis

Bekker P, Miland-Samuelsen AR, Smerdel MP, Schnack TH, Lauszus FF, Karstensen SH
Int J Gynecol Cancer 2023 Dec 4;33(12):1921-1927. doi: 10.1136/ijgc-2023-004945. PMID: 37907261
Guo Y, Wang J, Li Y, Wang Y
Arch Gynecol Obstet 2020 Jul;302(1):203-208. Epub 2020 May 19 doi: 10.1007/s00404-020-05588-1. PMID: 32430758
Durmuş Y, Kılıç Ç, Çakır C, Yüksel D, Boran N, Karalök A, Boyraz G, Turan AT
J Obstet Gynaecol Res 2019 Jul;45(7):1311-1318. Epub 2019 May 20 doi: 10.1111/jog.13977. PMID: 31106943
Gressel GM, Buza N, Pal L
Eur J Gynaecol Oncol 2017;38(2):214-220. PMID: 29953783
Schultz KA, Harris AK, Schneider DT, Young RH, Brown J, Gershenson DM, Dehner LP, Hill DA, Messinger YH, Frazier AL
J Oncol Pract 2016 Oct;12(10):940-946. doi: 10.1200/JOP.2016.016261. PMID: 27858560Free PMC Article

Therapy

Wang G, Zhang R, Li C, Chen A
J Ovarian Res 2021 Nov 4;14(1):150. doi: 10.1186/s13048-021-00909-7. PMID: 34736487Free PMC Article
Ordulu Z, Young RH
Am J Surg Pathol 2021 Jan;45(1):59-67. doi: 10.1097/PAS.0000000000001544. PMID: 32815828
Gressel GM, Buza N, Pal L
Eur J Gynaecol Oncol 2017;38(2):214-220. PMID: 29953783
Zhang HY, Zhu JE, Huang W, Zhu J
Int J Clin Exp Pathol 2014;7(10):6956-64. Epub 2014 Sep 15 PMID: 25400781Free PMC Article
Xiao H, Li B, Zuo J, Feng X, Li X, Zhang R, Wu L
Gynecol Endocrinol 2013 Mar;29(3):192-5. Epub 2012 Nov 23 doi: 10.3109/09513590.2012.738723. PMID: 23173550

Prognosis

Wang G, Zhang R, Li C, Chen A
J Ovarian Res 2021 Nov 4;14(1):150. doi: 10.1186/s13048-021-00909-7. PMID: 34736487Free PMC Article
Yuan Z, Huo X, Jiang D, Yu M, Cao D, Wu H, Shen K, Yang J, Zhang Y, Zhou H, Wang Y
Oncologist 2020 Sep;25(9):e1396-e1405. Epub 2020 Aug 11 doi: 10.1634/theoncologist.2020-0110. PMID: 32557933Free PMC Article
Guo Y, Wang J, Li Y, Wang Y
Arch Gynecol Obstet 2020 Jul;302(1):203-208. Epub 2020 May 19 doi: 10.1007/s00404-020-05588-1. PMID: 32430758
Castro BGR, Souza CP, Andrade CEMDC, Vieira MA, Andrade DAP, Reis RD
Rev Bras Ginecol Obstet 2019 Jul;41(7):440-448. Epub 2019 Jul 25 doi: 10.1055/s-0039-1693056. PMID: 31344718Free PMC Article
Gressel GM, Buza N, Pal L
Eur J Gynaecol Oncol 2017;38(2):214-220. PMID: 29953783

Clinical prediction guides

McCluggage WG, Rivera B, Chong AS, Clarke BA, Schultz KAP, Dehner LP, Tchrakian N, Apellaniz-Ruiz M, Gilks CB, Kommoss F, Stewart CJR, Foulkes WD
Am J Surg Pathol 2023 Apr 1;47(4):490-496. Epub 2022 Dec 30 doi: 10.1097/PAS.0000000000002010. PMID: 36583307
Wang G, Zhang R, Li C, Chen A
J Ovarian Res 2021 Nov 4;14(1):150. doi: 10.1186/s13048-021-00909-7. PMID: 34736487Free PMC Article
Zhang Y, Ren M, Hong Y, Zhong Y, Cong X, Chen C, Liu Z, Man Y, Yang L
Medicine (Baltimore) 2020 Jul 2;99(27):e20806. doi: 10.1097/MD.0000000000020806. PMID: 32629665Free PMC Article
Schultz KA, Harris AK, Schneider DT, Young RH, Brown J, Gershenson DM, Dehner LP, Hill DA, Messinger YH, Frazier AL
J Oncol Pract 2016 Oct;12(10):940-946. doi: 10.1200/JOP.2016.016261. PMID: 27858560Free PMC Article
Mooney EE, Nogales FF, Bergeron C, Tavassoli FA
Histopathology 2002 Aug;41(2):110-7. doi: 10.1046/j.1365-2559.2002.01426.x. PMID: 12147087

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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