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Primary Cutaneous Mucinous Carcinoma

MedGen UID:
362690
Concept ID:
C1879641
Neoplastic Process
Synonyms: Adnexal Mucinous Adenocarcinoma; Adnexal Mucinous Carcinoma; Sweat Gland Mucinous Carcinoma

Definition

A rare low-grade carcinoma of the sweat glands. The most common sites are eyelids, scalp, axilla, face and trunk. It is histologically characterized by proliferating ducts until the overproduction of mucin creates islands of tumor cells, essentially floating in mucinous pools (Rosai J. Ackerman''s Surgical Pathology). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary Cutaneous Mucinous Carcinoma

Professional guidelines

PubMed

Freeman T, Russell AJ, Council ML
Dermatol Surg 2023 Dec 1;49(12):1091-1095. Epub 2023 Aug 29 doi: 10.1097/DSS.0000000000003921. PMID: 37643246
Rismiller KP, Crowe DR, Knackstedt TJ
Dermatol Surg 2020 Sep;46(9):1141-1147. doi: 10.1097/DSS.0000000000002263. PMID: 31702595

Recent clinical studies

Etiology

Adkins KE, Busam K, Pulitzer M
Am J Surg Pathol 2023 Oct 1;47(10):1186-1191. Epub 2023 Aug 3 doi: 10.1097/PAS.0000000000002107. PMID: 37530225Free PMC Article
Rismiller KP, Crowe DR, Knackstedt TJ
Dermatol Surg 2020 Sep;46(9):1141-1147. doi: 10.1097/DSS.0000000000002263. PMID: 31702595
Ansari AN, Bobos M, Shih S, Chen MC, Ardakani NM, Rosales CM, Chen CJ, Savage C, Bracey T, McKee PH, Cerruto CA
Am J Dermatopathol 2019 Aug;41(8):571-577. doi: 10.1097/DAD.0000000000001370. PMID: 31335409
Kamalpour L, Brindise RT, Nodzenski M, Bach DQ, Veledar E, Alam M
JAMA Dermatol 2014 Apr;150(4):380-4. doi: 10.1001/jamadermatol.2013.6006. PMID: 24452370
Stranahan D, Cherpelis BS, Glass LF, Ladd S, Fenske NA
Dermatol Surg 2009 Jul;35(7):1023-34. Epub 2009 Apr 16 doi: 10.1111/j.1524-4725.2009.01179.x. PMID: 19397647

Diagnosis

Grushchak S, Barlow T, Palla B, Mannor GE, Greenway HT, Kelley BF
Cutis 2023 Sep;112(3):E6-E10. doi: 10.12788/cutis.0856. PMID: 37903397
Freeman T, Russell AJ, Council ML
Dermatol Surg 2023 Dec 1;49(12):1091-1095. Epub 2023 Aug 29 doi: 10.1097/DSS.0000000000003921. PMID: 37643246
Sung KY, Lee S, Lee SY
J Craniofac Surg 2022 Nov-Dec 01;33(8):e806-e808. Epub 2022 Jun 29 doi: 10.1097/SCS.0000000000008672. PMID: 36409851
Behbahani S, Pinto JO, Wassef D, Povolotskiy R, Paskhover B
J Craniofac Surg 2021 May 1;32(3):e244-e247. doi: 10.1097/SCS.0000000000006968. PMID: 32890173
Cardoso JC, Calonje E
Histopathology 2015 Nov;67(5):589-606. Epub 2015 Jul 21 doi: 10.1111/his.12767. PMID: 26114606

Therapy

Kelly Á, Anand R, Natkunarajah J, Samarasinghe V, Craythorne E
Clin Exp Dermatol 2023 Jul 7;48(7):778-780. doi: 10.1093/ced/llad057. PMID: 36787279
Sung YN, Park CS, Roh J, Choi JW, Choi SH, Lee Y, Cho KJ
J Cutan Pathol 2018 Dec;45(12):886-890. Epub 2018 Oct 4 doi: 10.1111/cup.13349. PMID: 30178542
Matin RN, Gibbon K, Rizvi H, Harwood CA, Cerio R
Am J Dermatopathol 2011 Oct;33(7):705-9. doi: 10.1097/DAD.0b013e3181f9c83d. PMID: 21885944

Prognosis

Freeman T, Russell AJ, Council ML
Dermatol Surg 2023 Dec 1;49(12):1091-1095. Epub 2023 Aug 29 doi: 10.1097/DSS.0000000000003921. PMID: 37643246
Behbahani S, Pinto JO, Wassef D, Povolotskiy R, Paskhover B
J Craniofac Surg 2021 May 1;32(3):e244-e247. doi: 10.1097/SCS.0000000000006968. PMID: 32890173
Rismiller KP, Crowe DR, Knackstedt TJ
Dermatol Surg 2020 Sep;46(9):1141-1147. doi: 10.1097/DSS.0000000000002263. PMID: 31702595
Ansari AN, Bobos M, Shih S, Chen MC, Ardakani NM, Rosales CM, Chen CJ, Savage C, Bracey T, McKee PH, Cerruto CA
Am J Dermatopathol 2019 Aug;41(8):571-577. doi: 10.1097/DAD.0000000000001370. PMID: 31335409
Kamalpour L, Brindise RT, Nodzenski M, Bach DQ, Veledar E, Alam M
JAMA Dermatol 2014 Apr;150(4):380-4. doi: 10.1001/jamadermatol.2013.6006. PMID: 24452370

Clinical prediction guides

Behbahani S, Pinto JO, Wassef D, Povolotskiy R, Paskhover B
J Craniofac Surg 2021 May 1;32(3):e244-e247. doi: 10.1097/SCS.0000000000006968. PMID: 32890173
Ansari AN, Bobos M, Shih S, Chen MC, Ardakani NM, Rosales CM, Chen CJ, Savage C, Bracey T, McKee PH, Cerruto CA
Am J Dermatopathol 2019 Aug;41(8):571-577. doi: 10.1097/DAD.0000000000001370. PMID: 31335409
Sung YN, Park CS, Roh J, Choi JW, Choi SH, Lee Y, Cho KJ
J Cutan Pathol 2018 Dec;45(12):886-890. Epub 2018 Oct 4 doi: 10.1111/cup.13349. PMID: 30178542
Kamalpour L, Brindise RT, Nodzenski M, Bach DQ, Veledar E, Alam M
JAMA Dermatol 2014 Apr;150(4):380-4. doi: 10.1001/jamadermatol.2013.6006. PMID: 24452370
Scilletta A, Soma PF, Grasso G, Scilletta R, Pompili G, Tarico MS, Perrotta RE
G Chir 2011 Jun-Jul;32(6-7):323-5. PMID: 21771401

Recent systematic reviews

Kamalpour L, Brindise RT, Nodzenski M, Bach DQ, Veledar E, Alam M
JAMA Dermatol 2014 Apr;150(4):380-4. doi: 10.1001/jamadermatol.2013.6006. PMID: 24452370

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