U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rectal medullary carcinoma

MedGen UID:
364314
Concept ID:
C1882915
Neoplastic Process
Synonyms: Rectal Medullary Carcinoma; rectal medullary carcinoma
 
Monarch Initiative: MONDO:0020801

Definition

A rare, invasive rectal adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis. [from NCI]

Professional guidelines

PubMed

Nikolaou A, Thomas D, Kampanellou C, Alexandraki K, Andersson LG, Sundin A, Kaltsas G
J Endocrinol Invest 2010 Dec;33(11):794-9. Epub 2010 Mar 22 doi: 10.1007/BF03350344. PMID: 20332708

Recent clinical studies

Etiology

van den Broek MFM, Rijks EBG, Nikkels PGJ, Wolters VM, van Es RJJ, van Santen HM, van Nesselrooij BPM, Vriens MR, van Leeuwaarde RS, Valk GD, Verrijn Stuart AA
Endocrine 2021 Jun;72(3):905-914. Epub 2021 Jan 21 doi: 10.1007/s12020-021-02607-2. PMID: 33474713Free PMC Article
Bertelsen CA, Neuenschwander AU, Jansen JE, Wilhelmsen M, Kirkegaard-Klitbo A, Tenma JR, Bols B, Ingeholm P, Rasmussen LA, Jepsen LV, Iversen ER, Kristensen B, Gögenur I; Danish Colorectal Cancer Group
Lancet Oncol 2015 Feb;16(2):161-8. Epub 2014 Dec 31 doi: 10.1016/S1470-2045(14)71168-4. PMID: 25555421
Ogawa M, Watanabe M, Eto K, Kosuge M, Yamagata T, Kobayashi T, Yamazaki K, Anazawa S, Yanaga K
Hepatogastroenterology 2008 May-Jun;55(84):907-11. PMID: 18705295
Bütter A, Gagné J, Al-Jazaeri A, Emran MA, Deal C, St-Vil D
J Pediatr Surg 2007 Jan;42(1):203-6. doi: 10.1016/j.jpedsurg.2006.09.019. PMID: 17208566
Navarro J, Sonsino E, Boige N, Nabarra B, Ferkadji L, Mashako LM, Cezard JP
J Pediatr Gastroenterol Nutr 1990 Aug;11(2):179-95. doi: 10.1097/00005176-199008000-00006. PMID: 2395057

Diagnosis

Kanno DT, Mattos RLM, Campos FG, Siqueira RM, Carvalho RB, Real Martinez CA
Arq Bras Cir Dig 2023;35:e1702. Epub 2023 Jan 9 doi: 10.1590/0102-672020220002e1702. PMID: 36629684Free PMC Article
Jabbal IS, Nagarajan A, Rivera C, Yaghi M, Liang H, Nahleh Z, Bejarano P, Berho M, Wexner S
Surg Oncol 2022 Dec;45:101856. Epub 2022 Sep 29 doi: 10.1016/j.suronc.2022.101856. PMID: 36446307
van den Broek MFM, Rijks EBG, Nikkels PGJ, Wolters VM, van Es RJJ, van Santen HM, van Nesselrooij BPM, Vriens MR, van Leeuwaarde RS, Valk GD, Verrijn Stuart AA
Endocrine 2021 Jun;72(3):905-914. Epub 2021 Jan 21 doi: 10.1007/s12020-021-02607-2. PMID: 33474713Free PMC Article
Jain S, Jain A, Onizuka N, Boukhar SA
Hawaii J Med Public Health 2014 Nov;73(11):348-52. PMID: 25414804Free PMC Article
Martucciello G, Lerone M, Bricco L, Tonini GP, Lombardi L, Del Rossi CG, Bernasconi S
Ital J Pediatr 2012 Mar 19;38:9. doi: 10.1186/1824-7288-38-9. PMID: 22429913Free PMC Article

Prognosis

Jabbal IS, Nagarajan A, Rivera C, Yaghi M, Liang H, Nahleh Z, Bejarano P, Berho M, Wexner S
Surg Oncol 2022 Dec;45:101856. Epub 2022 Sep 29 doi: 10.1016/j.suronc.2022.101856. PMID: 36446307
van den Broek MFM, Rijks EBG, Nikkels PGJ, Wolters VM, van Es RJJ, van Santen HM, van Nesselrooij BPM, Vriens MR, van Leeuwaarde RS, Valk GD, Verrijn Stuart AA
Endocrine 2021 Jun;72(3):905-914. Epub 2021 Jan 21 doi: 10.1007/s12020-021-02607-2. PMID: 33474713Free PMC Article
Shia J, Klimstra DS, Bagci P, Basturk O, Adsay NV
Semin Diagn Pathol 2012 Aug;29(3):142-53. doi: 10.1053/j.semdp.2012.02.001. PMID: 23062421
Martucciello G, Lerone M, Bricco L, Tonini GP, Lombardi L, Del Rossi CG, Bernasconi S
Ital J Pediatr 2012 Mar 19;38:9. doi: 10.1186/1824-7288-38-9. PMID: 22429913Free PMC Article
Ogawa M, Watanabe M, Eto K, Kosuge M, Yamagata T, Kobayashi T, Yamazaki K, Anazawa S, Yanaga K
Hepatogastroenterology 2008 May-Jun;55(84):907-11. PMID: 18705295

Clinical prediction guides

Bertelsen CA, Neuenschwander AU, Jansen JE, Wilhelmsen M, Kirkegaard-Klitbo A, Tenma JR, Bols B, Ingeholm P, Rasmussen LA, Jepsen LV, Iversen ER, Kristensen B, Gögenur I; Danish Colorectal Cancer Group
Lancet Oncol 2015 Feb;16(2):161-8. Epub 2014 Dec 31 doi: 10.1016/S1470-2045(14)71168-4. PMID: 25555421
Navarro J, Sonsino E, Boige N, Nabarra B, Ferkadji L, Mashako LM, Cezard JP
J Pediatr Gastroenterol Nutr 1990 Aug;11(2):179-95. doi: 10.1097/00005176-199008000-00006. PMID: 2395057
Hawkey CJ, Holmes CH, Smith PG, Austin EB, Baldwin RW
Br J Cancer 1986 Dec;54(6):871-5. doi: 10.1038/bjc.1986.255. PMID: 3026425Free PMC Article
Kimura N, Sasano N
Virchows Arch A Pathol Anat Histopathol 1986;410(3):247-51. doi: 10.1007/BF00710831. PMID: 3026083

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...