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Synchronous Lesion

MedGen UID:
364401
•Concept ID:
C1883252
•
Finding

Definition

Two or more primary lesions that are diagnosed at the same time in the same patient, or soon after the diagnosis of the first primary lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSynchronous Lesion

Professional guidelines

PubMed

Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature.
Nilsson LN, Keane MG, Shamali A, Millastre Bocos J, Marijinissen van Zanten M, Antila A, Verdejo Gil C, Del Chiaro M, Laukkarinen J
Pancreatology 2016 Nov-Dec;16(6):1028-1036. Epub 2016 Sep 20 doi: 10.1016/j.pan.2016.09.011. PMID: 27681503
Management and predictors of early mortality in elderly patients with iron deficiency anemia: a prospective study of 111 patients.
Nahon S, Lahmek P, Aras N, Poupardin C, Lesgourgues B, Macaigne G, Delas N
Gastroenterol Clin Biol 2007 Feb;31(2):169-74. doi: 10.1016/s0399-8320(07)89350-x. PMID: 17347626

Recent clinical studies

Etiology

Characteristics of synchronous and metachronous duodenal tumors and association with colorectal cancer: a supplementary analysis.
Yamasaki Y, Kato M, Takeuchi Y, Hoteya S, Oyama T, Nonaka S, Yoshimizu S, Yoshida M, Ohata K, Miura Y, Hara Y, Tsuji S, Dohi O, Ueyama H, Kurahara K, Tashima T, Abe N, Mitsuhashi T, Nakayama A, Oda I, Yahagi N
J Gastroenterol 2023 May;58(5):459-469. Epub 2023 Feb 27 doi: 10.1007/s00535-023-01964-1. PMID: 36847918
The Surface Morphology of Large Nonpedunculated Colonic Polyps Predicts Synchronous Large Lesions.
O'Sullivan T, Tate D, Sidhu M, Gupta S, Elhindi J, Byth K, Cronin O, Whitfield A, Craciun A, Singh R, Brown G, Raftopoulos S, Hourigan L, Moss A, Klein A, Heitman S, Williams S, Lee E, Burgess NG, Bourke MJ
Clin Gastroenterol Hepatol 2023 Aug;21(9):2270-2277.e1. Epub 2023 Feb 12 doi: 10.1016/j.cgh.2023.01.034. PMID: 36787836
Incidence of synchronous malignancies found during triple endoscopy in head and neck cancer.
Sawaf T, Quereshy HA, Cabrera CI, Abrol A, Tamaki A, Thuener J, Li S
Am J Otolaryngol 2022 Mar-Apr;43(2):103349. Epub 2021 Dec 24 doi: 10.1016/j.amjoto.2021.103349. PMID: 34991020
Synchronous and subsequent lesions of serrated adenomas and tubular adenomas of the colorectum.
Shimomura T, Hiyama T, Tanaka S, Yoshihara M, Arihiro K, Chayama K
Pathobiology 2010;77(5):273-7. Epub 2010 Nov 29 doi: 10.1159/000319874. PMID: 21116119
Synchronous colorectal carcinomas.
Kimura T, Iwagaki H, Fuchimoto S, Hizuta A, Orita K
Hepatogastroenterology 1994 Oct;41(5):409-12. PMID: 7851846

Diagnosis

Incidence of synchronous malignancies found during triple endoscopy in head and neck cancer.
Sawaf T, Quereshy HA, Cabrera CI, Abrol A, Tamaki A, Thuener J, Li S
Am J Otolaryngol 2022 Mar-Apr;43(2):103349. Epub 2021 Dec 24 doi: 10.1016/j.amjoto.2021.103349. PMID: 34991020
Performance of CT Colonography in Diagnosis of Synchronous Colonic Lesions in Patients With Occlusive Colorectal Cancer.
Flor N, Ceretti AP, Luigiano C, Brambillasca P, Savoldi AP, Verrusio C, Ferrari D
AJR Am J Roentgenol 2020 Feb;214(2):348-354. Epub 2019 Oct 31 doi: 10.2214/AJR.19.21810. PMID: 31670584
Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature.
Nilsson LN, Keane MG, Shamali A, Millastre Bocos J, Marijinissen van Zanten M, Antila A, Verdejo Gil C, Del Chiaro M, Laukkarinen J
Pancreatology 2016 Nov-Dec;16(6):1028-1036. Epub 2016 Sep 20 doi: 10.1016/j.pan.2016.09.011. PMID: 27681503
Tumours of the bladder: what does the urologist expect from imaging?
Rouprêt M
Diagn Interv Imaging 2012 Apr;93(4):291-6. Epub 2012 Mar 30 doi: 10.1016/j.diii.2012.01.017. PMID: 22464997
Synchronous colorectal carcinomas.
Kimura T, Iwagaki H, Fuchimoto S, Hizuta A, Orita K
Hepatogastroenterology 1994 Oct;41(5):409-12. PMID: 7851846

Therapy

The Surface Morphology of Large Nonpedunculated Colonic Polyps Predicts Synchronous Large Lesions.
O'Sullivan T, Tate D, Sidhu M, Gupta S, Elhindi J, Byth K, Cronin O, Whitfield A, Craciun A, Singh R, Brown G, Raftopoulos S, Hourigan L, Moss A, Klein A, Heitman S, Williams S, Lee E, Burgess NG, Bourke MJ
Clin Gastroenterol Hepatol 2023 Aug;21(9):2270-2277.e1. Epub 2023 Feb 12 doi: 10.1016/j.cgh.2023.01.034. PMID: 36787836
The Effect of Helicobacter pylori Eradication on the Metachronous Neoplasm after Endoscopic Resection for Gastric Dysplasia.
Song JH, Yang SY, Lim JH, Choi JM, Kim SG
Korean J Gastroenterol 2017 Jul 25;70(1):27-32. doi: 10.4166/kjg.2017.70.1.27. PMID: 28728313
Malignant transformation of germinoma 14 years after onset: Favorable efficacy of oral etoposide.
Fukuoka K, Yanagisawa T, Suzuki T, Shirahata M, Adachi J, Mishima K, Fujimaki T, Matsutani M, Nishikawa R
Pediatr Int 2015 Jun;57(3):483-6. Epub 2015 Feb 24 doi: 10.1111/ped.12559. PMID: 25712128
Combined adenocarcinoma-carcinoid tumor of transverse colon.
Bhattacharjee PK, Halder S
J Cancer Res Ther 2013 Oct-Dec;9(4):746-7. doi: 10.4103/0973-1482.126483. PMID: 24518735

Prognosis

The Surface Morphology of Large Nonpedunculated Colonic Polyps Predicts Synchronous Large Lesions.
O'Sullivan T, Tate D, Sidhu M, Gupta S, Elhindi J, Byth K, Cronin O, Whitfield A, Craciun A, Singh R, Brown G, Raftopoulos S, Hourigan L, Moss A, Klein A, Heitman S, Williams S, Lee E, Burgess NG, Bourke MJ
Clin Gastroenterol Hepatol 2023 Aug;21(9):2270-2277.e1. Epub 2023 Feb 12 doi: 10.1016/j.cgh.2023.01.034. PMID: 36787836
Incidence of synchronous malignancies found during triple endoscopy in head and neck cancer.
Sawaf T, Quereshy HA, Cabrera CI, Abrol A, Tamaki A, Thuener J, Li S
Am J Otolaryngol 2022 Mar-Apr;43(2):103349. Epub 2021 Dec 24 doi: 10.1016/j.amjoto.2021.103349. PMID: 34991020
Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature.
Nilsson LN, Keane MG, Shamali A, Millastre Bocos J, Marijinissen van Zanten M, Antila A, Verdejo Gil C, Del Chiaro M, Laukkarinen J
Pancreatology 2016 Nov-Dec;16(6):1028-1036. Epub 2016 Sep 20 doi: 10.1016/j.pan.2016.09.011. PMID: 27681503
Tumours of the bladder: what does the urologist expect from imaging?
Rouprêt M
Diagn Interv Imaging 2012 Apr;93(4):291-6. Epub 2012 Mar 30 doi: 10.1016/j.diii.2012.01.017. PMID: 22464997
Synchronous colorectal carcinomas.
Kimura T, Iwagaki H, Fuchimoto S, Hizuta A, Orita K
Hepatogastroenterology 1994 Oct;41(5):409-12. PMID: 7851846

Clinical prediction guides

The Surface Morphology of Large Nonpedunculated Colonic Polyps Predicts Synchronous Large Lesions.
O'Sullivan T, Tate D, Sidhu M, Gupta S, Elhindi J, Byth K, Cronin O, Whitfield A, Craciun A, Singh R, Brown G, Raftopoulos S, Hourigan L, Moss A, Klein A, Heitman S, Williams S, Lee E, Burgess NG, Bourke MJ
Clin Gastroenterol Hepatol 2023 Aug;21(9):2270-2277.e1. Epub 2023 Feb 12 doi: 10.1016/j.cgh.2023.01.034. PMID: 36787836
Performance of CT Colonography in Diagnosis of Synchronous Colonic Lesions in Patients With Occlusive Colorectal Cancer.
Flor N, Ceretti AP, Luigiano C, Brambillasca P, Savoldi AP, Verrusio C, Ferrari D
AJR Am J Roentgenol 2020 Feb;214(2):348-354. Epub 2019 Oct 31 doi: 10.2214/AJR.19.21810. PMID: 31670584
Tumours of the bladder: what does the urologist expect from imaging?
Rouprêt M
Diagn Interv Imaging 2012 Apr;93(4):291-6. Epub 2012 Mar 30 doi: 10.1016/j.diii.2012.01.017. PMID: 22464997
Synchronous and subsequent lesions of serrated adenomas and tubular adenomas of the colorectum.
Shimomura T, Hiyama T, Tanaka S, Yoshihara M, Arihiro K, Chayama K
Pathobiology 2010;77(5):273-7. Epub 2010 Nov 29 doi: 10.1159/000319874. PMID: 21116119
Synchronous colorectal carcinomas.
Kimura T, Iwagaki H, Fuchimoto S, Hizuta A, Orita K
Hepatogastroenterology 1994 Oct;41(5):409-12. PMID: 7851846

Recent systematic reviews

Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature.
Nilsson LN, Keane MG, Shamali A, Millastre Bocos J, Marijinissen van Zanten M, Antila A, Verdejo Gil C, Del Chiaro M, Laukkarinen J
Pancreatology 2016 Nov-Dec;16(6):1028-1036. Epub 2016 Sep 20 doi: 10.1016/j.pan.2016.09.011. PMID: 27681503

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