Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Crush syndrome

MedGen UID:: 3671
•Concept ID:: C0010392
•: Disease or Syndrome

Synonyms:	Crush Syndrome; Crush Syndromes; Syndrome, Crush; Syndromes, Crush
SNOMED CT:	Crush syndrome (23697004); Renal failure following crushing injury (23697004); Ischemic muscular necrosis syndrome (23697004); Bywaters' syndrome (23697004); Crush kidney (23697004)

Monarch Initiative:	MONDO:0043549

Definition

A medical condition characterized by major shock and renal failure after a crushing injury to skeletal muscle. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCrush syndrome

Disorder by Site
- Disorder of cardiovascular system
  - Abnormality of the cardiovascular system
    - Abnormal cardiovascular system physiology
      - Shock
        Traumatic shock
        Crush syndrome

Professional guidelines

PubMed

Emergency department management after the 2020 Aegean Sea - Izmir earthquake.

Uz İ, Çetin M, Songur Kodik M, Güvenç E, Karbek Akarca F, Ersel M
Ulus Travma Acil Cerrahi Derg 2022 Mar;28(3):361-368. doi: 10.14744/tjtes.2021.89679. PMID: 35485574 Free PMC Article

Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.

Cervellin G, Comelli I, Benatti M, Sanchis-Gomar F, Bassi A, Lippi G
Clin Biochem 2017 Aug;50(12):656-662. Epub 2017 Feb 21 doi: 10.1016/j.clinbiochem.2017.02.016. PMID: 28235546

Conservative treatment of thoracic outlet syndrome. A review of the literature.

Vanti C, Natalini L, Romeo A, Tosarelli D, Pillastrini P
Eura Medicophys 2007 Mar;43(1):55-70. Epub 2006 Sep 24 PMID: 16955064

See all (39)

Recent clinical studies

Etiology

Emergency department management after the 2020 Aegean Sea - Izmir earthquake.

Uz İ, Çetin M, Songur Kodik M, Güvenç E, Karbek Akarca F, Ersel M
Ulus Travma Acil Cerrahi Derg 2022 Mar;28(3):361-368. doi: 10.14744/tjtes.2021.89679. PMID: 35485574 Free PMC Article

Double crush syndrome: Epidemiology, diagnosis, and treatment results.

Ochoa-Cacique D, Córdoba-Mosqueda ME, Aguilar-Calderón JR, García-González U, Ibarra-De la Torre A, Reyes-Rodríguez VA, Lomelí-Ramírez JDJ, Medina-Carrillo Ó, Sánchez-Calderón MD, Castañeda-Ramírez EA
Neurochirurgie 2021 Apr;67(2):165-169. Epub 2020 Oct 29 doi: 10.1016/j.neuchi.2020.09.011. PMID: 33130027

Disasters, children and the kidneys.

Sever MS, Sever L, Vanholder R
Pediatr Nephrol 2020 Aug;35(8):1381-1393. Epub 2019 Aug 17 doi: 10.1007/s00467-019-04310-x. PMID: 31422466

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.

Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374 Free PMC Article

Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians.

Huerta-Alardín AL, Varon J, Marik PE
Crit Care 2005 Apr;9(2):158-69. Epub 2004 Oct 20 doi: 10.1186/cc2978. PMID: 15774072 Free PMC Article

See all (195)

Diagnosis

Crush injury and syndrome: A review for emergency clinicians.

Long B, Liang SY, Gottlieb M
Am J Emerg Med 2023 Jul;69:180-187. Epub 2023 Apr 25 doi: 10.1016/j.ajem.2023.04.029. PMID: 37163784

Double crush syndrome: Epidemiology, diagnosis, and treatment results.

Emerging medical therapies in crush syndrome - progress report from basic sciences and potential future avenues.

Li N, Wang X, Wang P, Fan H, Hou S, Gong Y
Ren Fail 2020 Nov;42(1):656-666. doi: 10.1080/0886022X.2020.1792928. PMID: 32662306 Free PMC Article

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.

Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374 Free PMC Article

Double Crush Syndrome.

Kane PM, Daniels AH, Akelman E
J Am Acad Orthop Surg 2015 Sep;23(9):558-62. doi: 10.5435/JAAOS-D-14-00176. PMID: 26306807

See all (186)

Therapy

Emerging medical therapies in crush syndrome - progress report from basic sciences and potential future avenues.

Li N, Wang X, Wang P, Fan H, Hou S, Gong Y
Ren Fail 2020 Nov;42(1):656-666. doi: 10.1080/0886022X.2020.1792928. PMID: 32662306 Free PMC Article

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.

Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374 Free PMC Article

Rhabdomyolysis.

Sever MS
Acta Clin Belg 2007;62 Suppl 2:375-9. doi: 10.1179/acb.2007.084. PMID: 18284003

Conservative treatment of thoracic outlet syndrome. A review of the literature.

Vanti C, Natalini L, Romeo A, Tosarelli D, Pillastrini P
Eura Medicophys 2007 Mar;43(1):55-70. Epub 2006 Sep 24 PMID: 16955064

Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians.

Huerta-Alardín AL, Varon J, Marik PE
Crit Care 2005 Apr;9(2):158-69. Epub 2004 Oct 20 doi: 10.1186/cc2978. PMID: 15774072 Free PMC Article

See all (93)

Prognosis

Acute Kidney Injury in Active Wars and Other Man-Made Disasters.

Sever MS, Vanholder R, Lameire N
Semin Nephrol 2020 Jul;40(4):341-353. doi: 10.1016/j.semnephrol.2020.06.001. PMID: 32800285

Double Crush Syndrome.

Kane PM, Daniels AH, Akelman E
J Am Acad Orthop Surg 2015 Sep;23(9):558-62. doi: 10.5435/JAAOS-D-14-00176. PMID: 26306807

Rhabdomyolysis.

de Wolff JF
Br J Hosp Med (Lond) 2012 Feb;73(2):C30-2. doi: 10.12968/hmed.2012.73.sup2.c30. PMID: 22504713

Crush syndrome.

Gonzalez D
Crit Care Med 2005 Jan;33(1 Suppl):S34-41. doi: 10.1097/01.ccm.0000151065.13564.6f. PMID: 15640677

Crush injury--crush syndrome.

Michaelson M, Reis ND
Unfallchirurg 1988 Jul;91(7):330-2. PMID: 3064309

See all (146)

Clinical prediction guides

10 Hypotheses in Hand Surgery.

Tang JB
Hand Clin 2022 Aug;38(3):357-366. doi: 10.1016/j.hcl.2022.04.003. PMID: 35985761

Double crush syndrome: Epidemiology, diagnosis, and treatment results.

Wars, disasters and kidneys.

Lameire N
Acta Clin Belg 2014 Dec;69(6):418-25. doi: 10.1179/0001551214Z.00000000087. PMID: 25409904

Crush syndrome.

Gonzalez D
Crit Care Med 2005 Jan;33(1 Suppl):S34-41. doi: 10.1097/01.ccm.0000151065.13564.6f. PMID: 15640677

Crush syndrome: pathophysiology and management.

Peck SA
Orthop Nurs 1990 May-Jun;9(3):33-40. PMID: 2198518

See all (103)

Recent systematic reviews

The Ethical Triage and Management Guidelines of the Entrapped and Mangled Extremity in Resource Scarce Environments: A Systematic Literature Review.

Weinstein E, Gosney JE, Ragazzoni L, Franc J, Herbert T, Weinstein B, Verde M, Zeller J, Wolfson N, Boyce W, Cramer J
Disaster Med Public Health Prep 2021 Jun;15(3):389-397. Epub 2020 May 27 doi: 10.1017/dmp.2020.49. PMID: 32456743

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.

Chavez LO, Leon M, Einav S, Varon J
Crit Care 2016 Jun 15;20(1):135. doi: 10.1186/s13054-016-1314-5. PMID: 27301374 Free PMC Article

Wound management in disaster settings.

Wuthisuthimethawee P, Lindquist SJ, Sandler N, Clavisi O, Korin S, Watters D, Gruen RL
World J Surg 2015 Apr;39(4):842-53. doi: 10.1007/s00268-014-2663-3. PMID: 25085100 Free PMC Article

Prevention of kidney injury following rhabdomyolysis: a systematic review.

Scharman EJ, Troutman WG
Ann Pharmacother 2013 Jan;47(1):90-105. Epub 2013 Jan 16 doi: 10.1345/aph.1R215. PMID: 23324509

Hyperbaric oxygen therapy in the management of carbon monoxide poisoning, osteoradionecrosis, burns, skin grafts, and crush injury.

Saunders PJ
Int J Technol Assess Health Care 2003 Summer;19(3):521-5. doi: 10.1017/s026646230300045x. PMID: 12962338

See all (5)

MedGen

National Center for Biotechnology Information

Send to:

Crush syndrome

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity