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Flatulence, CTCAE

MedGen UID:
368077
•Concept ID:
C1962956
•
Finding

Definition

A disorder characterized by a discharge of excessive gas from the lower GI tract. [from NCI]

Professional guidelines

PubMed

One-Year Treatment-Related Side Effects and Quality of Life After Chemoradiotherapy in Squamous Cell Carcinoma of the Anus.
Lefèvre AC, Serup-Hansen E, Storm KS, Wind KL, Kronborg C, Spindler KG
Int J Radiat Oncol Biol Phys 2023 Apr 1;115(5):1165-1177. Epub 2022 Sep 28 doi: 10.1016/j.ijrobp.2022.09.071. PMID: 36179989

Recent clinical studies

Etiology

Timing of High-Dose-Rate Brachytherapy With External Beam Radiation Therapy in Patients With Intermediate- and High-Risk Localized Prostate Cancer and Its Effects on Toxicity and Quality of Life: A Randomized Controlled Trial (THEPCA).
Choudhury M, Thomas SS, Cain A, Palvai S, Nageshwaran S, Zhang J, Hayden K, Cain A, Hoskin P, Ahmed I
Int J Radiat Oncol Biol Phys 2024 May 1;119(1):90-99. Epub 2023 Dec 30 doi: 10.1016/j.ijrobp.2023.11.011. PMID: 38163520
One-Year Treatment-Related Side Effects and Quality of Life After Chemoradiotherapy in Squamous Cell Carcinoma of the Anus.
Lefèvre AC, Serup-Hansen E, Storm KS, Wind KL, Kronborg C, Spindler KG
Int J Radiat Oncol Biol Phys 2023 Apr 1;115(5):1165-1177. Epub 2022 Sep 28 doi: 10.1016/j.ijrobp.2022.09.071. PMID: 36179989
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: Physician- and patient reported outcome from the EMBRACE study.
Jensen NBK, Pötter R, Kirchheiner K, Fokdal L, Lindegaard JC, Kirisits C, Mazeron R, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K; EMBRACE Collaborative Group
Radiother Oncol 2018 Jun;127(3):431-439. Epub 2018 Jun 4 doi: 10.1016/j.radonc.2018.05.016. PMID: 29880222
Structured gastroenterological intervention and improved outcome for patients with chronic gastrointestinal symptoms following pelvic radiotherapy.
Henson CC, Davidson SE, Ang Y, Babbs C, Crampton J, Kelly M, Lal S, Limdi JK, Whatley G, Swindell R, Makin W, McLaughlin J
Support Care Cancer 2013 Aug;21(8):2255-65. Epub 2013 Mar 21 doi: 10.1007/s00520-013-1782-y. PMID: 23512314

Diagnosis

Structured gastroenterological intervention and improved outcome for patients with chronic gastrointestinal symptoms following pelvic radiotherapy.
Henson CC, Davidson SE, Ang Y, Babbs C, Crampton J, Kelly M, Lal S, Limdi JK, Whatley G, Swindell R, Makin W, McLaughlin J
Support Care Cancer 2013 Aug;21(8):2255-65. Epub 2013 Mar 21 doi: 10.1007/s00520-013-1782-y. PMID: 23512314

Therapy

Timing of High-Dose-Rate Brachytherapy With External Beam Radiation Therapy in Patients With Intermediate- and High-Risk Localized Prostate Cancer and Its Effects on Toxicity and Quality of Life: A Randomized Controlled Trial (THEPCA).
Choudhury M, Thomas SS, Cain A, Palvai S, Nageshwaran S, Zhang J, Hayden K, Cain A, Hoskin P, Ahmed I
Int J Radiat Oncol Biol Phys 2024 May 1;119(1):90-99. Epub 2023 Dec 30 doi: 10.1016/j.ijrobp.2023.11.011. PMID: 38163520
One-Year Treatment-Related Side Effects and Quality of Life After Chemoradiotherapy in Squamous Cell Carcinoma of the Anus.
Lefèvre AC, Serup-Hansen E, Storm KS, Wind KL, Kronborg C, Spindler KG
Int J Radiat Oncol Biol Phys 2023 Apr 1;115(5):1165-1177. Epub 2022 Sep 28 doi: 10.1016/j.ijrobp.2022.09.071. PMID: 36179989
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: Physician- and patient reported outcome from the EMBRACE study.
Jensen NBK, Pötter R, Kirchheiner K, Fokdal L, Lindegaard JC, Kirisits C, Mazeron R, Mahantshetty U, Jürgenliemk-Schulz IM, Segedin B, Hoskin P, Tanderup K; EMBRACE Collaborative Group
Radiother Oncol 2018 Jun;127(3):431-439. Epub 2018 Jun 4 doi: 10.1016/j.radonc.2018.05.016. PMID: 29880222
Structured gastroenterological intervention and improved outcome for patients with chronic gastrointestinal symptoms following pelvic radiotherapy.
Henson CC, Davidson SE, Ang Y, Babbs C, Crampton J, Kelly M, Lal S, Limdi JK, Whatley G, Swindell R, Makin W, McLaughlin J
Support Care Cancer 2013 Aug;21(8):2255-65. Epub 2013 Mar 21 doi: 10.1007/s00520-013-1782-y. PMID: 23512314

Clinical prediction guides

Timing of High-Dose-Rate Brachytherapy With External Beam Radiation Therapy in Patients With Intermediate- and High-Risk Localized Prostate Cancer and Its Effects on Toxicity and Quality of Life: A Randomized Controlled Trial (THEPCA).
Choudhury M, Thomas SS, Cain A, Palvai S, Nageshwaran S, Zhang J, Hayden K, Cain A, Hoskin P, Ahmed I
Int J Radiat Oncol Biol Phys 2024 May 1;119(1):90-99. Epub 2023 Dec 30 doi: 10.1016/j.ijrobp.2023.11.011. PMID: 38163520
One-Year Treatment-Related Side Effects and Quality of Life After Chemoradiotherapy in Squamous Cell Carcinoma of the Anus.
Lefèvre AC, Serup-Hansen E, Storm KS, Wind KL, Kronborg C, Spindler KG
Int J Radiat Oncol Biol Phys 2023 Apr 1;115(5):1165-1177. Epub 2022 Sep 28 doi: 10.1016/j.ijrobp.2022.09.071. PMID: 36179989
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Structured gastroenterological intervention and improved outcome for patients with chronic gastrointestinal symptoms following pelvic radiotherapy.
Henson CC, Davidson SE, Ang Y, Babbs C, Crampton J, Kelly M, Lal S, Limdi JK, Whatley G, Swindell R, Makin W, McLaughlin J
Support Care Cancer 2013 Aug;21(8):2255-65. Epub 2013 Mar 21 doi: 10.1007/s00520-013-1782-y. PMID: 23512314

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