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Increased risk of leukemia

MedGen UID:
369978
•Concept ID:
C1969318
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased risk of leukemia

Professional guidelines

PubMed

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment.
Zhang L, Freeman LE, Nakamura J, Hecht SS, Vandenberg JJ, Smith MT, Sonawane BR
Environ Mol Mutagen 2010 Apr;51(3):181-91. doi: 10.1002/em.20534. PMID: 19790261Free PMC Article
Management of RBC-transfusion dependence.
Melchert M, List AF
Hematology Am Soc Hematol Educ Program 2007:398-404. doi: 10.1182/asheducation-2007.1.398. PMID: 18024657

Recent clinical studies

Etiology

Gut microbiome immaturity and childhood acute lymphoblastic leukaemia.
Peppas I, Ford AM, Furness CL, Greaves MF
Nat Rev Cancer 2023 Aug;23(8):565-576. Epub 2023 Jun 6 doi: 10.1038/s41568-023-00584-4. PMID: 37280427Free PMC Article
Epidemiology and Etiology of Leukemia and Lymphoma.
Bispo JAB, Pinheiro PS, Kobetz EK
Cold Spring Harb Perspect Med 2020 Jun 1;10(6) doi: 10.1101/cshperspect.a034819. PMID: 31727680Free PMC Article
Recognition and management of leukaemia in children.
Brayley J, Stanton LK, Jenner L, Paul SP
Br J Nurs 2019 Aug 8;28(15):985-992. doi: 10.12968/bjon.2019.28.15.985. PMID: 31393775
Acute myeloid leukaemia.
Short NJ, Rytting ME, Cortes JE
Lancet 2018 Aug 18;392(10147):593-606. Epub 2018 Aug 2 doi: 10.1016/S0140-6736(18)31041-9. PMID: 30078459Free PMC Article
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359

Diagnosis

Myelodysplastic syndromes: 2021 update on diagnosis, risk stratification and management.
Garcia-Manero G, Chien KS, Montalban-Bravo G
Am J Hematol 2020 Nov;95(11):1399-1420. doi: 10.1002/ajh.25950. PMID: 32744763
Epidemiology and Etiology of Leukemia and Lymphoma.
Bispo JAB, Pinheiro PS, Kobetz EK
Cold Spring Harb Perspect Med 2020 Jun 1;10(6) doi: 10.1101/cshperspect.a034819. PMID: 31727680Free PMC Article
Acute myeloid leukaemia.
Short NJ, Rytting ME, Cortes JE
Lancet 2018 Aug 18;392(10147):593-606. Epub 2018 Aug 2 doi: 10.1016/S0140-6736(18)31041-9. PMID: 30078459Free PMC Article
Hyperleukocytosis and leukostasis: management of a medical emergency.
Giammarco S, Chiusolo P, Piccirillo N, Di Giovanni A, Metafuni E, Laurenti L, Sica S, Pagano L
Expert Rev Hematol 2017 Feb;10(2):147-154. Epub 2016 Dec 26 doi: 10.1080/17474086.2017.1270754. PMID: 27967252
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359

Therapy

Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management.
Garcia-Manero G
Am J Hematol 2023 Aug;98(8):1307-1325. Epub 2023 Jun 8 doi: 10.1002/ajh.26984. PMID: 37288607
Epidemiology and Etiology of Leukemia and Lymphoma.
Bispo JAB, Pinheiro PS, Kobetz EK
Cold Spring Harb Perspect Med 2020 Jun 1;10(6) doi: 10.1101/cshperspect.a034819. PMID: 31727680Free PMC Article
Immunotherapy in pediatric acute lymphoblastic leukemia.
Inaba H, Pui CH
Cancer Metastasis Rev 2019 Dec;38(4):595-610. doi: 10.1007/s10555-019-09834-0. PMID: 31811553Free PMC Article
MDS overlap disorders and diagnostic boundaries.
Tanaka TN, Bejar R
Blood 2019 Mar 7;133(10):1086-1095. Epub 2019 Jan 22 doi: 10.1182/blood-2018-10-844670. PMID: 30670443
Acute myeloid leukaemia.
Short NJ, Rytting ME, Cortes JE
Lancet 2018 Aug 18;392(10147):593-606. Epub 2018 Aug 2 doi: 10.1016/S0140-6736(18)31041-9. PMID: 30078459Free PMC Article

Prognosis

Myelodysplastic syndromes: 2021 update on diagnosis, risk stratification and management.
Garcia-Manero G, Chien KS, Montalban-Bravo G
Am J Hematol 2020 Nov;95(11):1399-1420. doi: 10.1002/ajh.25950. PMID: 32744763
Epidemiology and Etiology of Leukemia and Lymphoma.
Bispo JAB, Pinheiro PS, Kobetz EK
Cold Spring Harb Perspect Med 2020 Jun 1;10(6) doi: 10.1101/cshperspect.a034819. PMID: 31727680Free PMC Article
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials.
Hills RK, Castaigne S, Appelbaum FR, Delaunay J, Petersdorf S, Othus M, Estey EH, Dombret H, Chevret S, Ifrah N, Cahn JY, Récher C, Chilton L, Moorman AV, Burnett AK
Lancet Oncol 2014 Aug;15(9):986-96. Epub 2014 Jul 6 doi: 10.1016/S1470-2045(14)70281-5. PMID: 25008258Free PMC Article
Leukaemia and pregnancy.
Fey MF, Surbek D
Recent Results Cancer Res 2008;178:97-110. doi: 10.1007/978-3-540-71274-9_10. PMID: 18080447

Clinical prediction guides

Predicted leukocyte telomere length and risk of myeloid neoplasms.
Sullivan SM, Cole B, Lane J, Meredith JJ, Langer E, Hooten AJ, Roesler M, McGraw KL, Pankratz N, Poynter JN
Hum Mol Genet 2023 Oct 4;32(20):2996-3005. doi: 10.1093/hmg/ddad126. PMID: 37531260Free PMC Article
Gut microbiome immaturity and childhood acute lymphoblastic leukaemia.
Peppas I, Ford AM, Furness CL, Greaves MF
Nat Rev Cancer 2023 Aug;23(8):565-576. Epub 2023 Jun 6 doi: 10.1038/s41568-023-00584-4. PMID: 37280427Free PMC Article
Myelodysplastic syndromes.
Li H, Hu F, Gale RP, Sekeres MA, Liang Y
Nat Rev Dis Primers 2022 Nov 17;8(1):74. doi: 10.1038/s41572-022-00402-5. PMID: 36396662
Myelodysplastic syndromes: 2021 update on diagnosis, risk stratification and management.
Garcia-Manero G, Chien KS, Montalban-Bravo G
Am J Hematol 2020 Nov;95(11):1399-1420. doi: 10.1002/ajh.25950. PMID: 32744763
Prediction of acute myeloid leukaemia risk in healthy individuals.
Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N, Niemeyer E, Barda N, Zuzarte PC, Heisler L, Sundaravadanam Y, Luben R, Hayat S, Wang TT, Zhao Z, Cirlan I, Pugh TJ, Soave D, Ng K, Latimer C, Hardy C, Raine K, Jones D, Hoult D, Britten A, McPherson JD, Johansson M, Mbabaali F, Eagles J, Miller JK, Pasternack D, Timms L, Krzyzanowski P, Awadalla P, Costa R, Segal E, Bratman SV, Beer P, Behjati S, Martincorena I, Wang JCY, Bowles KM, Quirós JR, Karakatsani A, La Vecchia C, Trichopoulou A, Salamanca-Fernández E, Huerta JM, Barricarte A, Travis RC, Tumino R, Masala G, Boeing H, Panico S, Kaaks R, Krämer A, Sieri S, Riboli E, Vineis P, Foll M, McKay J, Polidoro S, Sala N, Khaw KT, Vermeulen R, Campbell PJ, Papaemmanuil E, Minden MD, Tanay A, Balicer RD, Wareham NJ, Gerstung M, Dick JE, Brennan P, Vassiliou GS, Shlush LI
Nature 2018 Jul;559(7714):400-404. Epub 2018 Jul 9 doi: 10.1038/s41586-018-0317-6. PMID: 29988082Free PMC Article

Recent systematic reviews

Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis.
Isaksen IM, Dankel SN
Clin Nutr 2023 Jun;42(6):919-928. Epub 2023 Mar 30 doi: 10.1016/j.clnu.2023.03.018. PMID: 37087831
Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies.
Larsson SC, Burgess S
EBioMedicine 2022 Aug;82:104154. Epub 2022 Jul 8 doi: 10.1016/j.ebiom.2022.104154. PMID: 35816897Free PMC Article
Adjuvant and neoadjuvant breast cancer treatments: A systematic review of their effects on mortality.
Kerr AJ, Dodwell D, McGale P, Holt F, Duane F, Mannu G, Darby SC, Taylor CW
Cancer Treat Rev 2022 Apr;105:102375. Epub 2022 Mar 4 doi: 10.1016/j.ctrv.2022.102375. PMID: 35367784Free PMC Article
Philadelphia-Like Acute Lymphoblastic Leukemia: A Systematic Review.
Yadav V, Ganesan P, Veeramani R, Kumar V D
Clin Lymphoma Myeloma Leuk 2021 Jan;21(1):e57-e65. Epub 2020 Aug 18 doi: 10.1016/j.clml.2020.08.011. PMID: 33485429
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M
Lancet 2008 Feb 16;371(9612):569-78. doi: 10.1016/S0140-6736(08)60269-X. PMID: 18280327

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