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Healing scar

MedGen UID:
384469
Concept ID:
C2004491
Pathologic Function
Synonyms: Cicatrix; Scar; Scars
SNOMED CT: Scar (12402003); Scar tissue (12402003); Cicatrix (12402003); Fibrous scar (12402003); Scar (275322007); Healing scar (48677004); Scarring (48677004)

Definition

A permanent mark left on the skin in the process of wound healing. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHealing scar

Professional guidelines

PubMed

Roy MG, Davies LA, Guillen DE, Sequitin JD, Buchanan EP, Maricevich RS, Truong TA, Monson LA
J Craniofac Surg 2021 Oct 1;32(7):2282-2284. doi: 10.1097/SCS.0000000000007561. PMID: 33606437
Tanaydin V, Conings J, Malyar M, van der Hulst R, van der Lei B
Aesthet Surg J 2016 Sep;36(8):959-65. Epub 2016 Mar 14 doi: 10.1093/asj/sjw046. PMID: 26977069
Morgan ED, Bledsoe SC, Barker J
Am Fam Physician 2000 Nov 1;62(9):2015-26, 2029-30, 2032. PMID: 11087185

Recent clinical studies

Etiology

Morrison KA, Frey JD, Karp N, Choi M
Plast Reconstr Surg 2023 Feb 1;151(2):267-276. Epub 2022 Nov 8 doi: 10.1097/PRS.0000000000009828. PMID: 36696305
Zhao H, Liang T, Tang Y, Zhu D, Lin Q, Chen J, Fei J, Yu T, Zhang Y
Oxid Med Cell Longev 2022;2022:7887782. Epub 2022 Sep 13 doi: 10.1155/2022/7887782. PMID: 36148412Free PMC Article
Wieczorek E, Reszka E, Gromadzinska J, Wasowicz W
Neoplasma 2012;59(3):237-47. doi: 10.4149/neo_2012_031. PMID: 22296495
Haurani MJ, Foreman K, Yang JJ, Siddiqui A
Plast Reconstr Surg 2009 Jan;123(1):139-148. doi: 10.1097/PRS.0b013e3181904d1b. PMID: 19116547Free PMC Article
Atiyeh BS, Amm CA, El Musa KA
Aesthetic Plast Surg 2003 Sep-Oct;27(5):411-7. Epub 2003 Dec 4 doi: 10.1007/s00266-003-3049-3. PMID: 14648065

Diagnosis

Pienkowski T, Kowalczyk T, Garcia-Romero N, Ayuso-Sacido A, Ciborowski M
Biochim Biophys Acta Rev Cancer 2022 May;1877(3):188721. Epub 2022 Mar 16 doi: 10.1016/j.bbcan.2022.188721. PMID: 35304294
Carqueville JC, Chesnut C
Dermatol Surg 2021 Oct 1;47(10):1376-1378. doi: 10.1097/DSS.0000000000003178. PMID: 34352836
Gomes CM, Damasco Fdos S, Morais OO, Paula CD, Sampaio RN
An Bras Dermatol 2013 May-Jun;88(3):462-4. doi: 10.1590/abd1806-4841.20131885. PMID: 23793208Free PMC Article
Morgan ED, Bledsoe SC, Barker J
Am Fam Physician 2000 Nov 1;62(9):2015-26, 2029-30, 2032. PMID: 11087185
Elton RF
J Am Acad Dermatol 1983 Apr;8(4):513-9. doi: 10.1016/s0190-9622(83)70057-5. PMID: 6853784

Therapy

Morrison KA, Frey JD, Karp N, Choi M
Plast Reconstr Surg 2023 Feb 1;151(2):267-276. Epub 2022 Nov 8 doi: 10.1097/PRS.0000000000009828. PMID: 36696305
Hausauer AK, Humphrey S
Dermatol Surg 2020 Mar;46(3):348-357. doi: 10.1097/DSS.0000000000002147. PMID: 31714381
Gomes CM, Damasco Fdos S, Morais OO, Paula CD, Sampaio RN
An Bras Dermatol 2013 May-Jun;88(3):462-4. doi: 10.1590/abd1806-4841.20131885. PMID: 23793208Free PMC Article
Haurani MJ, Foreman K, Yang JJ, Siddiqui A
Plast Reconstr Surg 2009 Jan;123(1):139-148. doi: 10.1097/PRS.0b013e3181904d1b. PMID: 19116547Free PMC Article
Elton RF
J Am Acad Dermatol 1983 Apr;8(4):513-9. doi: 10.1016/s0190-9622(83)70057-5. PMID: 6853784

Prognosis

Ruiz-Villalba A, Romero JP, Hernández SC, Vilas-Zornoza A, Fortelny N, Castro-Labrador L, San Martin-Uriz P, Lorenzo-Vivas E, García-Olloqui P, Palacio M, Gavira JJ, Bastarrika G, Janssens S, Wu M, Iglesias E, Abizanda G, de Morentin XM, Lasaga M, Planell N, Bock C, Alignani D, Medal G, Prudovsky I, Jin YR, Ryzhov S, Yin H, Pelacho B, Gomez-Cabrero D, Lindner V, Lara-Astiaso D, Prósper F
Circulation 2020 Nov 10;142(19):1831-1847. Epub 2020 Sep 25 doi: 10.1161/CIRCULATIONAHA.119.044557. PMID: 32972203Free PMC Article
Richardson WJ, Clarke SA, Quinn TA, Holmes JW
Compr Physiol 2015 Sep 20;5(4):1877-909. doi: 10.1002/cphy.c140067. PMID: 26426470Free PMC Article
Wieczorek E, Reszka E, Gromadzinska J, Wasowicz W
Neoplasma 2012;59(3):237-47. doi: 10.4149/neo_2012_031. PMID: 22296495
Haurani MJ, Foreman K, Yang JJ, Siddiqui A
Plast Reconstr Surg 2009 Jan;123(1):139-148. doi: 10.1097/PRS.0b013e3181904d1b. PMID: 19116547Free PMC Article
Ngo P, Ramalingam P, Phillips JA, Furuta GT
Methods Mol Biol 2006;341:103-9. doi: 10.1385/1-59745-113-4:103. PMID: 16799192

Clinical prediction guides

Ma X, Zhao LL, Yu YC, Cheng Y
Genesis 2024 Feb;62(1):e23557. Epub 2023 Oct 13 doi: 10.1002/dvg.23557. PMID: 37830136
Zhao H, Liang T, Tang Y, Zhu D, Lin Q, Chen J, Fei J, Yu T, Zhang Y
Oxid Med Cell Longev 2022;2022:7887782. Epub 2022 Sep 13 doi: 10.1155/2022/7887782. PMID: 36148412Free PMC Article
Bhartiya P, Kaushik N, Nguyen LN, Bekeschus S, Masur K, Weltmann KD, Kaushik NK, Choi EH
Int J Mol Sci 2022 Mar 14;23(6) doi: 10.3390/ijms23063120. PMID: 35328541Free PMC Article
Richardson WJ, Clarke SA, Quinn TA, Holmes JW
Compr Physiol 2015 Sep 20;5(4):1877-909. doi: 10.1002/cphy.c140067. PMID: 26426470Free PMC Article
Ngo P, Ramalingam P, Phillips JA, Furuta GT
Methods Mol Biol 2006;341:103-9. doi: 10.1385/1-59745-113-4:103. PMID: 16799192

Recent systematic reviews

Hausauer AK, Humphrey S
Dermatol Surg 2020 Apr;46(4):447-456. doi: 10.1097/DSS.0000000000002148. PMID: 31770154
Edmondson SJ, Ali Jumabhoy I, Murray A
Burns 2018 Nov;44(7):1721-1737. Epub 2018 Feb 16 doi: 10.1016/j.burns.2018.01.012. PMID: 29456099

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